Search Results - "Strelkov, S. V."
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Structural basis of bacterial defense against g-type lysozyme-based innate immunity
Published in Cellular and molecular life sciences : CMLS (01-03-2013)“…Gram-negative bacteria can produce specific proteinaceous inhibitors to defend themselves against the lytic action of host lysozymes. So far, four different…”
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Thermonuclear Power Engineering: 60 Years of Research. What Comes Next?
Published in Physics of atomic nuclei (01-12-2017)“…This paper summarizes results of more than half a century of research of high-temperature plasmas heated to a temperature of more than 100 million degrees (10…”
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Three-Dimensional Structure of α-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6
Published in Journal of molecular biology (05-08-2011)“…Small heat shock proteins (sHSPs) are a family of evolutionary conserved ATP-independent chaperones. These proteins share a common architecture defined by a…”
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Stabilization of vimentin coil2 fragment via an engineered disulfide
Published in Journal of structural biology (2012)“…Cytoskeletal intermediate filaments (IFs) assemble from the elementary dimers based on a segmented α-helical coiled-coil (CC) structure. Crystallographic…”
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Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin‐activatable fibrinolysis inhibitor activation and activated thrombin‐activatable fibrinolysis inhibitor activity
Published in Journal of thrombosis and haemostasis (01-08-2016)“…Essentials Thrombin‐activatable fibrinolysis inhibitor (TAFI) is a risk factor for cardiovascular disorders. TAFI inhibitory nanobodies represent a promising…”
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THE IMPACT OF DOWNSIZING ON THE BANKRUPTCY OF RUSSIAN COMPANIES
Published in Strategičeskie rešeniâ i risk-menedžment (Online) (30-07-2019)“…Links between staff reductions and the company’s bankruptcyare identified. The empirical base of research included 650 companies (150 bankrupts) in the…”
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Coiled coils: a highly versatile protein folding motif
Published in Trends in Cell Biology (01-02-2001)“…The α-helical coiled coil is one of the principal subunit oligomerization motifs in proteins. Its most characteristic feature is a heptad repeat pattern of…”
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THE PROGRAM OF ADAPTATION AND PROFESSIONAL DEVELOPMENT OF PERSONNEL WITHIN A QUALITY MANAGEMENT SYSTEM OF THE PHARMACEUTICAL ORGANIZATION (REVIEW)
Published in Razrabotka i registraciâ lekarstvennyh sredstv (Online) (14-02-2019)“…Introduction. This article describes the procedure for personnel management in a pharmacy organization in terms of the current requirements of Good Pharmacy…”
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Molecular Basis of Bacterial Defense against Host Lysozymes: X-ray Structures of Periplasmic Lysozyme Inhibitors PliI and PliC
Published in Journal of molecular biology (04-02-2011)“…Lysozymes play a key role in the innate immune system of vertebrates and invertebrates by hydrolyzing peptidoglycan, a vital component of the bacterial cell…”
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Structure of Bacteriophage T4 Fibritin M: a Troublesome Packing Arrangement
Published in Acta crystallographica. Section D, Biological crystallography. (01-09-1998)“…Fibritin, a 52 kDa product of bacteriophage T4 gene wac, forms 530 Å long fibers, named whiskers, that attach to the phage neck and perform a helper function…”
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High quality structure of cleaved PAI-1-stab
Published in Journal of structural biology (01-02-2009)“…Here we report the crystal structure of a stablilized plasminogen activator inhibitor-1 variant (PAI-1-N150H-K154T-Q301P-Q319L-M354I (PAI-1-stab)) that shows a…”
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Divide-and-conquer crystallographic approach towards an atomic structure of intermediate filaments
Published in Journal of molecular biology (02-03-2001)“…Intermediate filaments (IFs) represent an essential component of the cytoskeleton in higher eukaryotic cells. The elementary building block of the IF…”
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The taming of small heat-shock proteins: crystallization of the α-crystallin domain from human Hsp27
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01-12-2009)“…Small heat‐shock proteins (sHsps) are ubiquitous molecular chaperones. sHsps function as homooligomers or heterooligomers that are prone to subunit exchange…”
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Structure of bacteriophage T4 fibritin: a segmented coiled coil and the role of the C-terminal domain
Published in Structure (London) (15-06-1997)“…Background: Oligomeric coiled-coil motifs are found in numerous protein structures; among them is fibritin, a structural protein of bacteriophage T4, which…”
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The intermediate filament protein consensus motif of helix 2B: its atomic structure and contribution to assembly
Published in Journal of molecular biology (19-05-2000)“…Nearly all intermediate filament proteins exhibit a highly conserved amino acid motif (YRKLLEGEE) at the C-terminal end of their central α-helical rod domain…”
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Small deletions disturb desmin architecture leading to breakdown of muscle cells and development of skeletal or cardioskeletal myopathy
Published in Human genetics (01-02-2004)“…Desmin ( DES) mutations have been recognized as a cause of desmin-related myopathy (OMIM 601419), or desminopathy, a disease characterized by progressive limb…”
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Crystallization and preliminary crystallographic characterization of bacteriophage T4 baseplate protein encoded by gene 9
Published in Journal of molecular biology (20-11-1993)“…The structural protein, gene product 9 (gp9), of bacteriophage T4 controls baseplate expansion at the first steps of virus attachment onto its host bacterial…”
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Design and Crystal Structure of Bacteriophage T4 Mini-Fibritin NCCF
Published in Journal of molecular biology (11-06-2004)“…Fibritin is a fibrous protein that forms “whiskers” attached to the neck of bacteriophage T4. Whiskers interact with the long tail fibers regulating the…”
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The structure of bacteriophage T4 gene product 9: the trigger for tail contraction
Published in Structure (London) (15-10-1999)“…Background: The T4 bacteriophage consists of a head, filled with double-stranded DNA, and a complex contractile tail required for the ejection of the viral…”
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