Search Results - "Strehl, S."

Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia by Nebral, K, Denk, D, Attarbaschi, A, König, M, Mann, G, Haas, O A, Strehl, S

“…PAX5 , a master regulator of B-cell development, was recently shown to be involved in several leukemia-associated rearrangements, which result in fusion genes…”
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Single-cell analysis identifies CRLF2 rearrangements as both early and late events in Down syndrome and non-Down syndrome acute lymphoblastic leukaemia by Potter, N., Jones, L., Blair, H., Strehl, S., Harrison, C. J., Greaves, M., Kearney, L., Russell, L. J.

“…Deregulated expression of the type I cytokine receptor, CRLF2 , is observed in 5–15% of precursor B-cell acute lymphoblastic leukaemia (B-ALL). We have…”
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All-trans retinoic acid and arsenic trioxide resistance of acute promyelocytic leukemia with the variant STAT5B-RARA fusion gene by Strehl, S, König, M, Boztug, H, Cooper, B W, Suzukawa, K, Zhang, S-J, Chen, H-Y, Attarbaschi, A, Dworzak, M N

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Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia by Meyer, C, Burmeister, T, Strehl, S, Schneider, B, Hubert, D, Zach, O, Haas, O, Klingebiel, T, Dingermann, T, Marschalek, R

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RT-PCR and FISH analysis of acute myeloid leukemia with t(8;16)(p11;p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical implications by SCHMIDT, H. H, STREHL, S, EMBERGER, W, HAAS, O. A, THALER, D, STRUNK, D, SILL, H, LINKESCH, W, JÄGER, U, SPERR, W, GREINIX, H. T, KÖNIG, M

“…The translocation t(8;16)(p11;p13) is associated with acute myeloid leukemia displaying monocytic differentiation (AML FAB M4/5) and fuses the MOZ (also named…”
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The human LASP1 gene is fused to MLL in an acute myeloid leukemia with t(11;17)(q23;q21) by STREHL, Sabine, BORKHARDT, Arndt, SLANY, Robert, FUCHS, Uta E, KÖNIG, Margit, HAAS, Oskar A

“…The MLL gene at chromosome 11q23 is frequently rearranged in acute leukemia. Here we report the identification of a new MLL fusion partner in the case of an…”
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Deletion of 11q23 is a highly specific nonrandom secondary genetic abnormality of ETV6/RUNX1-rearranged childhood acute lymphoblastic leukemia by Attarbaschi, A, Mann, G, Strehl, S, König, M, Steiner, M, Jeitler, V, Lion, Th, Dworzak, M N, Gadner, H, Haas, O A

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Deletion of 11q23 is a highly specific nonrandom secondary genetic abnormality of ETV6 RUNX1-rearranged childhood acute lymphoblastic leukaemia by Haas, O A, Lion, Th, Jeitler, V, Dworzak, M N, Steiner, M, Strehl, S, Attarbaschi, A, Gadner, H, Mann, G, Konig, M

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Prognostic impact of deletions at 1p36 and numerical aberrations in Ewing tumors by Hattinger, C.M., Rumpler, S., Strehl, S., Ambros, I.M., Zoubek, A., Pötschger, U., Gadner, H., Ambros, P.F.

“…Ewing's sarcoma, peripheral primitive neuroectodermal tumors, and Askin tumors are referred to as Ewing tumors (ETs), and are characterized by high MIC2…”
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The MLL recombinome of acute leukemias in 2017 by Meyer, C, Burmeister, T, Gröger, D, Tsaur, G, Fechina, L, Renneville, A, Sutton, R, Venn, N C, Emerenciano, M, Pombo-de-Oliveira, M S, Barbieri Blunck, C, Almeida Lopes, B, Zuna, J, Trka, J, Ballerini, P, Lapillonne, H, De Braekeleer, M, Cazzaniga, G, Corral Abascal, L, van der Velden, V H J, Delabesse, E, Park, T S, Oh, S H, Silva, M L M, Lund-Aho, T, Juvonen, V, Moore, A S, Heidenreich, O, Vormoor, J, Zerkalenkova, E, Olshanskaya, Y, Bueno, C, Menendez, P, Teigler-Schlegel, A, zur Stadt, U, Lentes, J, Göhring, G, Kustanovich, A, Aleinikova, O, Schäfer, B W, Kubetzko, S, Madsen, H O, Gruhn, B, Duarte, X, Gameiro, P, Lippert, E, Bidet, A, Cayuela, J M, Clappier, E, Alonso, C N, Zwaan, C M, van den Heuvel-Eibrink, M M, Izraeli, S, Trakhtenbrot, L, Archer, P, Hancock, J, Möricke, A, Alten, J, Schrappe, M, Stanulla, M, Strehl, S, Attarbaschi, A, Dworzak, M, Haas, O A, Panzer-Grümayer, R, Sedék, L, Szczepański, T, Caye, A, Suarez, L, Cavé, H, Marschalek, R

“…Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant, pediatric, adult and therapy-induced acute leukemias. Here we present the…”
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High-resolution analysis of DNA replication domain organization across an R/G-band boundary by Strehl, Sabine, LaSalle, Janine M., Lalande, Marc

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Neuroblastoma cells can actively eliminate supernumerary MYCN gene copies by micronucleus formation—sign of tumour cell revertance? by Ambros, I.M, Rumpler, S, Luegmayr, A, Hattinger, C.M, Strehl, S, Kovar, H, Gadner, H, Ambros, P.F

“…Human neuroblastoma cell lines frequently exhibit MYCN amplification and many are characterised by the presence of morphologically distinct cell types. The…”
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Variability of EWS chimaeric transcripts in Ewing tumours: a comparison of clinical and molecular data by Zoubek, A, Pfleiderer, C, Salzer-Kuntschik, M, Amann, G, Windhager, R, Fink, F M, Koscielniak, E, Delattre, O, Strehl, S, Ambros, P F

“…Ewing tumours (ET), including Ewing's sarcoma and peripheral primitive neuroectodermal tumour, are well characterised at the molecular level by a unique…”
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The KMT2A recombinome of acute leukemias in 2023 by Meyer, C., Larghero, P., Almeida Lopes, B., Burmeister, T., Gröger, D., Sutton, R., Venn, N. C., Cazzaniga, G., Corral Abascal, L., Tsaur, G., Fechina, L., Emerenciano, M., Pombo-de-Oliveira, M. S., Lund-Aho, T., Lundán, T., Montonen, M., Juvonen, V., Zuna, J., Trka, J., Ballerini, P., Lapillonne, H., Van der Velden, V. H. J., Sonneveld, E., Delabesse, E., de Matos, R. R. C., Silva, M. L. M., Bomken, S., Katsibardi, K., Keernik, M., Grardel, N., Mason, J., Price, R., Kim, J., Eckert, C., Lo Nigro, L., Bueno, C., Menendez, P., zur Stadt, U., Gameiro, P., Sedék, L., Szczepański, T., Bidet, A., Marcu, V., Shichrur, K., Izraeli, S., Madsen, H. O., Schäfer, B. W., Kubetzko, S., Kim, R., Clappier, E., Trautmann, H., Brüggemann, M., Archer, P., Hancock, J., Alten, J., Möricke, A., Stanulla, M., Lentes, J., Bergmann, A. K., Strehl, S., Köhrer, S., Nebral, K., Dworzak, M. N., Haas, O. A., Arfeuille, C., Caye-Eude, A., Cavé, H., Marschalek, R.

“…Chromosomal rearrangements of the human KMT2A/MLL gene are associated with de novo as well as therapy-induced infant, pediatric, and adult acute leukemias…”
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The MLL recombinome of acute leukemias in 2013 by Meyer, C, Hofmann, J, Burmeister, T, Gröger, D, Park, T S, Emerenciano, M, Pombo de Oliveira, M, Renneville, A, Villarese, P, Macintyre, E, Cavé, H, Clappier, E, Mass-Malo, K, Zuna, J, Trka, J, De Braekeleer, E, De Braekeleer, M, Oh, S H, Tsaur, G, Fechina, L, van der Velden, V H J, van Dongen, J J M, Delabesse, E, Binato, R, Silva, M L M, Kustanovich, A, Aleinikova, O, Harris, M H, Lund-Aho, T, Juvonen, V, Heidenreich, O, Vormoor, J, Choi, W W L, Jarosova, M, Kolenova, A, Bueno, C, Menendez, P, Wehner, S, Eckert, C, Talmant, P, Tondeur, S, Lippert, E, Launay, E, Henry, C, Ballerini, P, Lapillone, H, Callanan, M B, Cayuela, J M, Herbaux, C, Cazzaniga, G, Kakadiya, P M, Bohlander, S, Ahlmann, M, Choi, J R, Gameiro, P, Lee, D S, Krauter, J, Cornillet-Lefebvre, P, Te Kronnie, G, Schäfer, B W, Kubetzko, S, Alonso, C N, zur Stadt, U, Sutton, R, Venn, N C, Izraeli, S, Trakhtenbrot, L, Madsen, H O, Archer, P, Hancock, J, Cerveira, N, Teixeira, M R, Lo Nigro, L, Möricke, A, Stanulla, M, Schrappe, M, Sedék, L, Szczepański, T, Zwaan, C M, Coenen, E A, van den Heuvel-Eibrink, M M, Strehl, S, Dworzak, M, Panzer-Grümayer, R, Dingermann, T, Klingebiel, T, Marschalek, R

“…Chromosomal rearrangements of the human MLL (mixed lineage leukemia) gene are associated with high-risk infant, pediatric, adult and therapy-induced acute…”
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The PAX5‐JAK2 translocation acts as dual‐hit mutation that promotes aggressive B‐cell leukemia via nuclear STAT5 activation by Jurado, Sabine, Fedl, Anna S, Jaritz, Markus, Kostanova‐Poliakova, Daniela, Malin, Stephen G, Mullighan, Charles G, Strehl, Sabine, Fischer, Maria, Busslinger, Meinrad

“…While PAX5 is an important tumor suppressor gene in B‐cell acute lymphoblastic leukemia (B‐ALL), it is also involved in oncogenic translocations coding for…”
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Regression and progression in neuroblastoma. Does genetics predict tumour behaviour? by Ambros, P.F., Ambros, I.M., Strehl, S., Bauer, S., Luegmayr, A., Kovar, H., Ladenstein, R., Fink, F.-M., Horcher, E., Printz, G., Mutz, I., Schilling, F., Urban, C., Gadner, H.

“…Neuroblastoma (NB) is a heterogeneous disease. The clinical course may range from spontaneous regression and maturation to very aggressive behaviour. Stage 4s…”
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An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome by Harrison, C J, Moorman, A V, Schwab, C, Carroll, A J, Raetz, E A, Devidas, M, Strehl, S, Nebral, K, Harbott, J, Teigler-Schlegel, A, Zimmerman, M, Dastuge, N, Baruchel, A, Soulier, J, Auclerc, M-F, Attarbaschi, A, Mann, G, Stark, B, Cazzaniga, G, Chilton, L, Vandenberghe, P, Forestier, E, Haltrich, I, Raimondi, S C, Parihar, M, Bourquin, J-P, Tchinda, J, Haferlach, C, Vora, A, Hunger, S P, Heerema, N A, Haas, O A

“…Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic subgroup of childhood B-cell precursor acute lymphoblastic leukaemia…”
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Fluorescence in situ hybridization combined with immunohistochemistry for highly sensitive detection of chromosome 1 aberrations in neuroblastoma by Strehl, S, Ambros, P F

“…The development and application of a highly sensitive double-target fluorescence in situ hybridization (FISH) method in combination with immunohistochemistry…”
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New insights to the MLL recombinome of acute leukemias by Meyer, C, Kowarz, E, Hofmann, J, Renneville, A, Zuna, J, Trka, J, Ben Abdelali, R, Macintyre, E, De Braekeleer, E, De Braekeleer, M, Delabesse, E, de Oliveira, M P, Cavé, H, Clappier, E, van Dongen, J J M, Balgobind, B V, van den Heuvel-Eibrink, M M, Beverloo, H B, Panzer-Grümayer, R, Teigler-Schlegel, A, Harbott, J, Kjeldsen, E, Schnittger, S, Koehl, U, Gruhn, B, Heidenreich, O, Chan, L C, Yip, S F, Krzywinski, M, Eckert, C, Möricke, A, Schrappe, M, Alonso, C N, Schäfer, B W, Krauter, J, Lee, D A, zur Stadt, U, Te Kronnie, G, Sutton, R, Izraeli, S, Trakhtenbrot, L, Lo Nigro, L, Tsaur, G, Fechina, L, Szczepanski, T, Strehl, S, Ilencikova, D, Molkentin, M, Burmeister, T, Dingermann, T, Klingebiel, T, Marschalek, R

“…Chromosomal rearrangements of the human MLL gene are associated with high-risk pediatric, adult and therapy-associated acute leukemias. These patients need to…”
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