Search Results - "Streeter, Philip R"

Human islets contain four distinct subtypes of β cells by Dorrell, Craig, Schug, Jonathan, Canaday, Pamela S., Russ, Holger A., Tarlow, Branden D., Grompe, Maria T., Horton, Tamara, Hebrok, Matthias, Streeter, Philip R., Kaestner, Klaus H., Grompe, Markus

“…Human pancreatic islets of Langerhans contain five distinct endocrine cell types, each producing a characteristic hormone. The dysfunction or loss of the…”
Get full text

Targeted delivery of harmine to xenografted human pancreatic islets promotes robust cell proliferation by Mishra, Swati, Streeter, Philip R.

“…Type 1 diabetes (T1D) occurs as a consequence of the autoimmune destruction of insulin-producing pancreatic beta (β) cells and commonly presents with insulin…”
Get full text

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors by Cogger, Kathryn F., Sinha, Ankit, Sarangi, Farida, McGaugh, Emily C., Saunders, Diane, Dorrell, Craig, Mejia-Guerrero, Salvador, Aghazadeh, Yasaman, Rourke, Jillian L., Screaton, Robert A., Grompe, Markus, Streeter, Philip R., Powers, Alvin C., Brissova, Marcela, Kislinger, Thomas, Nostro, M. Cristina

“…PDX1 + /NKX6-1 + pancreatic progenitors (PPs) give rise to endocrine cells both in vitro and in vivo. This cell population can be successfully differentiated…”
Get full text

The Potential of Human Allogeneic Juvenile Chondrocytes for Restoration of Articular Cartilage by Adkisson, H. Davis, Martin, James A., Amendola, Richard L., Milliman, Curt, Mauch, Kelsey A., Katwal, Arbindra B., Seyedin, Mitchell, Amendola, Annuziato, Streeter, Philip R., Buckwalter, Joseph A.

“…Background: Donor-site morbidity, limited numbers of cells, loss of phenotype during ex vivo expansion, and age-related decline in chondrogenic activity…”
Get full text

Identification of a Novel Subset of Human Airway Epithelial Basal Stem Cells by Cheng, Christopher, Katoch, Parul, Zhong, Yong-Ping, Higgins, Claire T, Moredock, Maria, Chang, Matthew E K, Flory, Mark R, Randell, Scott H, Streeter, Philip R

“…The basal cell maintains the airway's respiratory epithelium as the putative resident stem cell. Basal cells are known to self-renew and differentiate into…”
Get full text

Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a "U-shaped" relationship by Shi, Mingjun, Flores, Brianna, Li, Peng, Gillings, Nancy, McMillan, Kathryn L, Ye, Jianfeng, Huang, Lily Jun-Shen, Sidhu, Sachdev S, Zhong, Yong-Ping, Grompe, Maria T, Streeter, Philip R, Moe, Orson W, Hu, Ming Chang

“…The erythropoietin receptor (EpoR) is widely expressed but its renoprotective action is unexplored. To examine the role of EpoR in vivo in the kidney, we…”
Get more information

New markers for tracking endoderm induction and hepatocyte differentiation from human pluripotent stem cells by Holtzinger, Audrey, Streeter, Philip R, Sarangi, Farida, Hillborn, Scott, Niapour, Maryam, Ogawa, Shinichiro, Keller, Gordon

“…The efficient generation of hepatocytes from human pluripotent stem cells (hPSCs) requires the induction of a proper endoderm population, broadly characterized…”
Get full text

The organoid-initiating cells in mouse pancreas and liver are phenotypically and functionally similar by Dorrell, Craig, Tarlow, Branden, Wang, Yuhan, Canaday, Pamela S., Haft, Annelise, Schug, Jonathan, Streeter, Philip R., Finegold, Milton J., Shenje, Lincoln T., Kaestner, Klaus H., Grompe, Markus

“…Pancreatic Lgr5 expression has been associated with organoid-forming epithelial progenitor populations but the identity of the organoid-initiating epithelial…”
Get full text

Hematopoietic stem cells contribute to lymphatic endothelium by Jiang, Shuguang, Bailey, Alexis S, Goldman, Devorah C, Swain, John R, Wong, Melissa H, Streeter, Philip R, Fleming, William H

“…Although the lymphatic system arises as an extension of venous vessels in the embryo, little is known about the role of circulating progenitors in the…”
Get full text

The novel monoclonal antibody HPC2 and N-cadherin distinguish pancreatic ductal adenocarcinoma from cholangiocarcinoma by Hooper, Jody E., MD, Morgan, Terry K., MD, PhD, Grompe, Markus, MD, Sheppard, Brett C., MD, Troxell, Megan L., MD, PhD, Corless, Christopher L., MD, PhD, Streeter, Philip R., PhD

“…Summary Metastatic pancreatic ductal adenocarcinoma and primary cholangiocarcinoma are morphologically very similar and, therefore, challenging to distinguish…”
Get full text

Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers by Dorrell, Craig, Abraham, Stephanie L, Lanxon-Cookson, Kelsea M, Canaday, Pamela S, Streeter, Philip R, Grompe, Markus

“…We have developed a novel panel of cell-surface markers for the isolation and study of all major cell types of the human pancreas. Hybridomas were selected…”
Get more information

Generation of Monoclonal Antibodies Specific for Cell Surface Molecules Expressed on Early Mouse Endoderm by Gadue, Paul, Gouon‐Evans, Valerie, Cheng, Xin, Wandzioch, Ewa, Zaret, Kenneth S, Grompe, Markus, Streeter, Philip R., Keller, Gordon M.

“…The development of functional cell populations such as hepatocytes and pancreatic β cells from embryonic stem cell (ESC) is dependent on the efficient…”
Get full text

Epigenomic plasticity enables human pancreatic α to β cell reprogramming by Bramswig, Nuria C, Everett, Logan J, Schug, Jonathan, Dorrell, Craig, Liu, Chengyang, Luo, Yanping, Streeter, Philip R, Naji, Ali, Grompe, Markus, Kaestner, Klaus H

“…Insulin-secreting β cells and glucagon-secreting α cells maintain physiological blood glucose levels, and their malfunction drives diabetes development. Using…”
Get full text

Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations by Smith, Nicholas R, Swain, John R, Davies, Paige S, Gallagher, Alexandra C, Parappilly, Michael S, Beach, Catherine Z, Streeter, Philip R, Williamson, Ian A, Magness, Scott T, Wong, Melissa H

“…Background & Aims Continual renewal of the intestinal epithelium is dependent on active- and slow-cycling stem cells that are confined to the crypt base. Tight…”
Get full text

Novel surface markers directed against adult human gallbladder by Galivo, Feorillo H., Dorrell, Craig, Grompe, Maria T., Zhong, YongPing, Streeter, Philip R., Grompe, Markus

“…Novel cell surface-reactive monoclonal antibodies generated against extrahepatic biliary cells were developed for the isolation and characterization of…”
Get full text

Micelle-Based Nanocarriers for Targeted Delivery of Cargo to Pancreas by Mishra, Swati, Streeter, Philip R

“…Innovations in the field of amphiphilic block copolymers have led to the development of a series of attractive polymer-based drug and gene delivery micellar…”
Get more information

Abnormal Development of Peripheral Lymphoid Organs in Mice Deficient in Lymphotoxin by De Togni, Pietro, Goellner, Joseph, Ruddle, Nancy H., Streeter, Philip R., Fick, Andrea, Mariathasan, Sanjeev, Smith, Stacy C., Carlson, Rebecca, Shornick, Laurie P., Strauss-Schoenberger, Jena, Russell, John H., Karr, Robert, Chaplin, David D.

“…Mice rendered deficient in lymphotoxin (LT) by gene targeting in embryonic stem cells have no morphologically detectable lymph nodes or Peyer's patches,…”
Get full text

Development of a scalable method to isolate subsets of stem cell-derived pancreatic islet cells by Parent, Audrey V., Ashe, Sudipta, Nair, Gopika G., Li, Mei-Lan, Chavez, Jessica, Liu, Jennifer S., Zhong, Yongping, Streeter, Philip R., Hebrok, Matthias

“…Cell replacement therapy using β cells derived from stem cells is a promising alternative to conventional diabetes treatment options. Although current…”
Get full text

Humanised recombinant antibody fragments bind human pancreatic islet cells by Buenafe, Abigail C., Streeter, Philip R.

“…We describe here the humanisation of two mouse monoclonal antibodies that bind to surface markers on human pancreatic islet endocrine cells. Monoclonal…”
Get full text

We’ve got 99 problems but prompt reporting ain’t one of them by Saunders, Kim E., Jarrell, Vickie, Streeter, Philip R.

Get full text