Search Results - "Streeper, Ryan S"
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SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells
Published in The Journal of biological chemistry (15-10-2010)“…SIRT4, a member of the sirtuin family, has been implicated in the regulation of insulin secretion by modulation of glutamate dehydrogenase. However, the role…”
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2
DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes[S]
Published in Journal of lipid research (01-04-2011)“…The total contribution of the acyl CoA:diacylglycerol acyltransferase (DGAT) enzymes, DGAT1 and DGAT2, to mammalian triacylglycerol (TG) synthesis has not been…”
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3
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
Published in Molecular and Cellular Biology (01-12-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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4
Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects
Published in Proceedings of the National Academy of Sciences - PNAS (17-10-2006)“…A pluripotent cell line, C3H10T1/2, is induced to undergo adipogenesis by a mixture of factors that includes a glucocorticoid such as dexamethasone. We found…”
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5
Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin
Published in The Journal of biological chemistry (13-02-2009)“…Retinoic acid (RA) is a potent signaling molecule that is essential for many biological processes, and its levels are tightly regulated by mechanisms that are…”
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6
DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation
Published in The Journal of clinical investigation (01-03-2010)“…Diet-induced obesity (DIO) leads to inflammatory activation of macrophages in white adipose tissue (WAT) and subsequently to insulin resistance. PPARgamma…”
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7
A growth-differentiation factor 15 receptor agonist in randomized placebo-controlled trials in healthy or obese persons
Published in The journal of clinical endocrinology and metabolism (16-08-2024)“…Growth Differentiation Factor 15 (GDF15), a divergent member of the TGF-β superfamily, signals via the hindbrain glial-derived neurotrophic factor receptor…”
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The Three Insulin Response Sequences in the Glucose-6-phosphatase Catalytic Subunit Gene Promoter Are Functionally Distinct
Published in The Journal of biological chemistry (04-04-2003)“…Glucose-6-phosphatase catalyzes the terminal step in the gluconeogenic and glycogenolytic pathways. In HepG2 cells, the maximum repression of basal…”
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9
Effects of DGAT1 deficiency on energy and glucose metabolism are independent of adiponectin
Published in American journal of physiology: endocrinology and metabolism (01-08-2006)“…Mice lacking acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1), an enzyme that catalyzes the terminal step in triacylglycerol synthesis, have enhanced insulin…”
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10
Identification and characterization of human GDF15 knockouts
Published in Nature metabolism (26-09-2024)“…Growth differentiation factor 15 (GDF15) is a secreted protein that regulates food intake, body weight and stress responses in pre-clinical models 1 . The…”
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Hepatocyte Nuclear Factor-1 Acts as an Accessory Factor to Enhance the Inhibitory Action of Insulin on Mouse Glucose-6-Phosphatase Gene Transcription
Published in Proceedings of the National Academy of Sciences - PNAS (04-08-1998)“…Glucose-6-phosphatase catalyzes the terminal step in the gluconeogenic and glycogenolytic pathways. Transcription of the gene encoding the…”
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12
Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice
Published in Aging (Albany, NY.) (01-01-2012)“…Calorie restriction results in leanness, which is linked to metabolic conditions that favor longevity. We show here that deficiency of the triglyceride…”
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13
Accessory Elements, Flanking DNA Sequence, and Promoter Context Play Key Roles in Determining the Efficacy of Insulin and Phorbol Ester Signaling through the Malic Enzyme and Collagenase-1 AP-1 Motifs
Published in The Journal of biological chemistry (02-08-2002)“…Insulin stimulates malic enzyme (ME)-chloramphenicol acetyltransferase (CAT) and collagenase-1-CAT fusion gene expression in H4IIE cells through identical…”
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A Multicomponent Insulin Response Sequence Mediates a Strong Repression of Mouse Glucose-6-phosphatase Gene Transcription by Insulin
Published in The Journal of biological chemistry (02-05-1997)“…Glucose-6-phosphatase (G6Pase) catalyzes the final step in the gluconeogenic and glycogenolytic pathways. The transcription of the gene encoding the catalytic…”
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15
Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence
Published in Diabetes (New York, N.Y.) (01-09-1999)“…Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the…”
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Differential Role of Hepatocyte Nuclear Factor-1 in the Regulation of Glucose-6-phosphatase Catalytic Subunit Gene Transcription by cAMP in Liver- and Kidney-derived Cell Lines
Published in The Journal of biological chemistry (21-04-2000)“…In liver and kidney, the terminal step in gluconeogenesis is catalyzed by glucose-6-phosphatase. To examine the effect of the cAMP signal transduction pathway…”
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Protein Kinase A Phosphorylates Hepatocyte Nuclear Factor-6 and Stimulates Glucose-6-phosphatase Catalytic Subunit Gene Transcription
Published in The Journal of biological chemistry (01-06-2001)“…Glucose-6-phosphatase is a multicomponent system that catalyzes the terminal step in gluconeogenesis. To examine the effect of the cAMP signal transduction…”
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A Phorbol Ester-Insensitive AP-1 Motif Mediates the Stimulatory Effect of Insulin on Rat Malic Enzyme Gene Transcription
Published in Molecular endocrinology (Baltimore, Md.) (01-11-1998)“…In liver, insulin stimulates the transcription of the gene encoding the cytosolic form of malic enzyme (ME) and modulates protein binding to two putative…”
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Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene
Published in Diabetes (New York, N.Y.) (01-03-1999)“…Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene. D H Ebert , L J Bischof , R S Streeper , S C Chapman…”
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20
Voluntary exercise training enhances glucose transport in muscle stimulated by insulin-like growth factor I
Published in Journal of applied physiology (1985) (01-02-1997)“…Jason Y. Hokama, Ryan S. Streeper, and Erik J. Henriksen Muscle Metabolism Laboratory, Department of Physiology, University of Arizona College of Medicine,…”
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