Search Results - "Strawbridge, Stanley E"
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Spatial profiling of early primate gastrulation in utero
Published in Nature (London) (01-09-2022)“…Gastrulation controls the emergence of cellular diversity and axis patterning in the early embryo. In mammals, this transformation is orchestrated by dynamic…”
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insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology
Published in Biology open (15-09-2023)“…A crucial aspect of embryology is relating the position of individual cells to the broader geometry of the embryo. A classic example of this is the first…”
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Deriving Human Naïve Embryonic Stem Cell Lines from Donated Supernumerary Embryos Using Physical Distancing and Signal Inhibition
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Until recently, naïve pluripotent stem cell lines were not captured from human embryos because protocols were based upon those devised for murine embryonic…”
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OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms
Published in Proceedings of the National Academy of Sciences - PNAS (19-01-2021)“…OCT4 is a fundamental component of the molecular circuitry governing pluripotency in vivo and in vitro. To determine how OCT4 establishes and protects the…”
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Human naive epiblast cells possess unrestricted lineage potential
Published in Cell stem cell (03-06-2021)“…Classic embryological experiments have established that the early mouse embryo develops via sequential lineage bifurcations. The first segregated lineage is…”
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