Search Results - "Stravitz, R."

Acute liver failure by Stravitz, R Todd, Lee, William M

“…Acute liver failure is a rare and severe consequence of abrupt hepatocyte injury, and can evolve over days or weeks to a lethal outcome. A variety of insults…”
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Rebalanced Hemostasis in Patients with Acute Liver Failure by Lisman, Ton, Stravitz, R Todd

“…Patients with acute liver failure (ALF) have substantial alterations in their hemostatic system. Since an international normalized ratio of ≥ 1.5 is part of…”
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Introduction to the revised American Association for the Study of Liver Diseases position paper on acute liver failure 2011 by Lee, William M., Stravitz, R. Todd, Larson, Anne M.

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Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy by Bajaj, Jasmohan S, Heuman, Douglas M, Sanyal, Arun J, Hylemon, Phillip B, Sterling, Richard K, Stravitz, R Todd, Fuchs, Michael, Ridlon, Jason M, Daita, Kalyani, Monteith, Pamela, Noble, Nicole A, White, Melanie B, Fisher, Andmorgan, Sikaroodi, Masoumeh, Rangwala, Huzefa, Gillevet, Patrick M

“…Hepatic encephalopathy (HE) represents a dysfunctional gut-liver-brain axis in cirrhosis which can negatively impact outcomes. This altered gut-brain…”
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The Multi-Dimensional Burden of Cirrhosis and Hepatic Encephalopathy on Patients and Caregivers by BAJAJ, Jasmohan S, WADE, James B, BELL, Debulon E, GILLES, Hochong, MORTON, Katherine, NOBLE, Nicole, PURI, Puneet, SANYAL, Arun J, GIBSON, Douglas P, HEUMAN, Douglas M, THACKER, Leroy R, STERLING, Richard K, TODD STRAVITZ, R, LUKETIC, Velimir, FUCHS, Michael, WHITE, Melanie B

“…Cirrhosis and hepatic encephalopathy (HE) can adversely affect survival, but their effect on socioeconomic and emotional burden on the family is not clear. The…”
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Minimal effects of acute liver injury/acute liver failure on hemostasis as assessed by thromboelastography by Stravitz, R. Todd, Lisman, Ton, Luketic, Velimir A, Sterling, Richard K, Puri, Puneet, Fuchs, Michael, Ibrahim, Ashraf, Lee, William M, Sanyal, Arun J

“…Background & Aims Patients with acute liver injury/failure (ALI/ALF) are assumed to have a bleeding diathesis on the basis of elevated INR; however, clinically…”
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Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis by Bajaj, J. S., Heuman, D. M., Hylemon, P. B., Sanyal, A. J., Puri, P., Sterling, R. K., Luketic, V., Stravitz, R. T., Siddiqui, M. S., Fuchs, M., Thacker, L. R., Wade, J. B., Daita, K., Sistrun, S., White, M. B., Noble, N. A., Thorpe, C., Kakiyama, G., Pandak, W. M., Sikaroodi, M., Gillevet, P. M.

“…Summary Background Safety of individual probiotic strains approved under Investigational New Drug (IND) policies in cirrhosis with minimal hepatic…”
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Proton Pump Inhibitor Initiation and Withdrawal affects Gut Microbiota and Readmission Risk in Cirrhosis by Bajaj, Jasmohan S, Acharya, Chathur, Fagan, Andrew, White, Melanie B, Gavis, Edith, Heuman, Douglas M, Hylemon, Phillip B, Fuchs, Michael, Puri, Puneet, Schubert, Mitchell L, Sanyal, Arun J, Sterling, Richard K, Stravitz, Todd R, Siddiqui, Mohammad S, Luketic, Velimir, Lee, Hannah, Sikaroodi, Masoumeh, Gillevet, Patrick M

“…Cirrhosis is associated with gut microbial dysbiosis, high readmissions and proton pump inhibitor (PPI) overuse, which could be inter-linked. Our aim was to…”
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An unbalance between von Willebrand factor and ADAMTS13 in acute liver failure: Implications for hemostasis and clinical outcome by Hugenholtz, Greg C. G., Adelmeijer, Jelle, Meijers, Joost C. M., Porte, Robert J., Stravitz, R. Todd, Lisman, Ton

“…Emerging evidence supports the concept of a rebalanced hemostatic state in liver disease as a result of a commensurate decline in prohemostatic and…”
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Bleeding in Patients With Cirrhosis Undergoing Invasive Cardiovascular Procedures: Do We Overestimate Risk? by Vetrovec, George, Stravitz, R. Todd

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VWF/ADAMTS13 Imbalance, But Not Global Coagulation or Fibrinolysis, Is Associated With Outcome and Bleeding in Acute Liver Failure by Driever, Ellen G., Stravitz, R. Todd, Zhang, Jingwen, Adelmeijer, Jelle, Durkalski, Valerie, Lee, William M., Lisman, Ton

“…Background and Aims Recent studies of acute liver failure (ALF) in man and animals have suggested that rebalanced hemostasis occurs, with distinct…”
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Bleeding complications in acute liver failure by Stravitz, R. Todd, Ellerbe, Caitlyn, Durkalski, Valerie, Schilsky, Michael, Fontana, Robert J., Peterseim, Carolyn, Lee, William M.

“…In patients with acute liver failure (ALF), elevated prothrombin time and thrombocytopenia can fuel a perception of a bleeding tendency. However, the…”
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Outcomes of Acute Liver Injury in Adults Due to Wilson’s Disease: Is Survival Without Transplant Possible? by Camarata, Michelle A., Gottfried, Michelle, Rule, Jody A., Ala, Aftab, Lee, William M., Todd Stravitz, R., Schilsky, Michael L.

“…Wilson’s disease (WD) is a rare cause of acute liver failure (ALF) that is thought to have a uniformly fatal outcome without liver transplantation (LT)…”
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Future directions in acute liver failure by Stravitz, R Todd, Fontana, Robert J, Karvellas, Constantine, Durkalski, Valerie, McGuire, Brendan, Rule, Jody A, Tujios, Shannan, Lee, William M

“…Acute liver failure (ALF) describes a clinical syndrome of rapid hepatocyte injury leading to liver failure manifested by coagulopathy and encephalopathy in…”
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Intravenous N -Acetylcysteine Improves Transplant-Free Survival in Early Stage Non-Acetaminophen Acute Liver Failure by Lee, William M, Hynan, Linda S, Rossaro, Lorenzo, Fontana, Robert J, Stravitz, R. Todd, Larson, Anne M, Davern, Timothy J, Murray, Natalie G, McCashland, Timothy, Reisch, Joan S, Robuck, Patricia R

“…Background & Aims N -acetylcysteine (NAC), an antidote for acetaminophen poisoning, might benefit patients with non–acetaminophen-related acute liver failure…”
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Role of procoagulant microparticles in mediating complications and outcome of acute liver injury/acute liver failure by Stravitz, R. Todd, Bowling, Regina, Bradford, Robert L., Key, Nigel S., Glover, Sam, Thacker, Leroy R., Gabriel, Don A.

“…Microparticles (MPs), membrane fragments of 0.1‐1.0 μm, are derived from many cell types in response to systemic inflammation. Acute liver failure (ALF) is a…”
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Thrombocytopenia Is Associated With Multi-organ System Failure in Patients With Acute Liver Failure by Stravitz, R. Todd, Ellerbe, Caitlyn, Durkalski, Valerie, Reuben, Adrian, Lisman, Ton, Lee, William M

“…Background & Aims Acute liver failure (ALF) is a syndrome characterized by an intense systemic inflammatory response (SIRS) and multi-organ system failure…”
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Generation of neutrophil extracellular traps in patients with acute liver failure is associated with poor outcome by Meijenfeldt, Fien A., Stravitz, R. Todd, Zhang, Jingwen, Adelmeijer, Jelle, Zen, Yoh, Durkalski, Valerie, Lee, William M., Lisman, Ton

“…Background and Aims Acute liver failure (ALF) is characterized by significant changes in the hemostatic system and by systemic inflammation. The formation of…”
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Critical management decisions in patients with acute liver failure by Stravitz, R Todd

“…Few admissions to the ICU present a greater clinical challenge than the patient with acute liver failure (ALF), the syndrome of abrupt loss of liver function…”
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Algorithms for managing coagulation disorders in liver disease by Stravitz, R. Todd

“…Patients with advanced liver disease have traditionally been considered at risk for bleeding complications. However, although bleeding in patients with…”
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