Search Results - "Strauss, Laura"

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  1. 1

    Revisiting the PD-1 pathway by Patsoukis, Nikolaos, Wang, Qi, Strauss, Laura, Boussiotis, Vassiliki A

    Published in Science advances (01-09-2020)
    “…Programmed Death-1 (PD-1; CD279) is an inhibitory receptor induced in activated T cells. PD-1 engagement by its ligands, PD-L1 and PD-L2, maintains peripheral…”
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  2. 2

    Targeted deletion of PD-1 in myeloid cells induces antitumor immunity by Strauss, Laura, Mahmoud, Mohamed A A, Weaver, Jessica D, Tijaro-Ovalle, Natalia M, Christofides, Anthos, Wang, Qi, Pal, Rinku, Yuan, Min, Asara, John, Patsoukis, Nikolaos, Boussiotis, Vassiliki A

    Published in Science immunology (03-01-2020)
    “…PD-1, a T cell checkpoint receptor and target of cancer immunotherapy, is also expressed on myeloid cells. The role of myeloid-specific versus T cell-specific…”
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  3. 3

    Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy by Le Bourgeois, Thibault, Strauss, Laura, Aksoylar, Halil-Ibrahim, Daneshmandi, Saeed, Seth, Pankaj, Patsoukis, Nikolaos, Boussiotis, Vassiliki A

    Published in Frontiers in oncology (03-08-2018)
    “…There has been significant progress in utilizing our immune system against cancer, mainly by checkpoint blockade and T cell-mediated therapies. The field of…”
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    Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin by Strauss, Laura, Czystowska, Malgorzata, Szajnik, Marta, Mandapathil, Magis, Whiteside, Theresa L

    Published in PloS one (22-06-2009)
    “…The immunosuppressive drug rapamycin (RAPA) promotes the expansion of CD4(+) CD25(high)Foxp3(+) regulatory T cells via mechanisms that remain unknown. Here, we…”
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    Increased Frequency and Suppression by Regulatory T Cells in Patients with Acute Myelogenous Leukemia by SZCZEPANSKI, Miroslaw J, SZAJNIK, Marta, CZYSTOWSKA, Malgorzata, MANDAPATHIL, Magis, STRAUSS, Laura, WELSH, Ann, FOON, Kenneth A, WHITESIDE, Theresa L, BOYIADZIS, Michael

    Published in Clinical cancer research (15-05-2009)
    “…Purpose: Regulatory CD4 + CD25 high Foxp3 + T cells (Treg) control peripheral immune tolerance. Patients with cancer, including those with hematologic…”
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  7. 7

    T Regulatory Type 1 Cells in Squamous Cell Carcinoma of the Head and Neck: Mechanisms of Suppression and Expansion in Advanced Disease by BERGMANN, Christoph, STRAUSS, Laura, YUN WANG, SZCZEPANSKI, Miroslaw J, LANG, Stephan, JOHNSON, Jonas T, WHITESIDE, Theresa L

    Published in Clinical cancer research (15-06-2008)
    “…Purpose: Regulatory T cells play a major role in tumor escape from immunosurveillance. T regulatory cells type 1 (Tr1), a subset of regulatory T cells present…”
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  8. 8

    Origin and Functions of Tumor-Associated Myeloid Cells (TAMCs) by Sica, Antonio, Porta, Chiara, Morlacchi, Sara, Banfi, Stefania, Strauss, Laura, Rimoldi, Monica, Totaro, Maria Grazia, Riboldi, Elena

    Published in Cancer microenvironment (01-08-2012)
    “…The construction of an inflammatory microenvironment provides the fuel for cancer development and progression. Hence, solid tumors promote the expansion and…”
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    Enhanced detection of nanostructures by scanning electron microscopy using insulating materials by O'Shea, Aaron, Wallace, Jeff, Hummel, Matt, Strauss, Laura H., Kidd, Timothy E.

    Published in Micron (Oxford, England : 1993) (01-09-2013)
    “…•Technique developed to better detect 1D sub-micron structures in scanning electron microscope.•Insulators in contact with 1D structures created halo-like…”
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  11. 11

    Signaling Abnormalities, Apoptosis, and Reduced Proliferation of Circulating and Tumor-infiltrating Lymphocytes in Patients with Oral Carcinoma by REICHERT, Torsten E, STRAUSS, Laura, WAGNER, Eva M, GOODING, William, WHITESIDE, Theresa L

    Published in Clinical cancer research (01-10-2002)
    “…We have reported earlier that T cells found in the tumor microenvironment of head and neck cancer showed evidence of apoptosis as well as decreased expression…”
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  12. 12

    Universal Method for Creating Optically Active Nanostructures on Layered Materials by Kidd, Timothy E, O’Shea, Aaron, Beck, Benjamin, He, Rui, Delaney, Conor, Shand, Paul M, Strauss, Laura H, Stollenwerk, Andrew, Hurley, Noah, Spurgeon, Kyle, Gu, Genda

    Published in Langmuir (27-05-2014)
    “…The ability to form patterned surface nanostructures has revolutionized the miniaturization of electronics and led to the discovery of emergent behaviors…”
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  13. 13

    Emergence of Long Range One-Dimensional Nanostructures in a Disordered Two-Dimensional System: Mn-Doped Ti1+δS2 by Stollenwerk, Andrew J, O’Shea, Aaron, Wolter, Erik, Roth, Michael W, Strauss, Laura H, Kidd, Timothy E

    Published in Journal of physical chemistry. C (12-01-2012)
    “…Multiple microscopic techniques have been employed to study Mn-intercalated Ti1+δS2 at different length scales. The introduction of Mn intercalates resulted in…”
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  14. 14

    Energy metabolism drives myeloid‐derived suppressor cell differentiation and functions in pathology by Sica, Antonio, Strauss, Laura

    Published in Journal of leukocyte biology (01-08-2017)
    “…Review on the functional relationship between cell metabolism and differentiation of myeloid suppressor cells, highlighting the importance in cancer and…”
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  15. 15

    Dopant Enhanced Etching of TiSe2 by Scanning Tunneling Microscopy by Kidd, Timothy E, Gamb, Brett I, Skirtachenko, Polina I, Strauss, Laura H

    Published in Langmuir (06-07-2010)
    “…The surfaces of pure and Mn doped TiSe2 were etched using a scanning tunneling microscope. Both types of samples were found to etch easily when scanning was…”
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  16. 16

    Synthesis of freestanding HfO2 nanostructures by Kidd, Timothy, O'Shea, Aaron, Boyle, Kayla, Wallace, Jeff, Strauss, Laura

    Published in Nanoscale research letters (05-04-2011)
    “…Two new methods for synthesizing nanostructured HfO 2 have been developed. The first method entails exposing HfTe 2 powders to air. This simple process…”
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  17. 17

    The complex role of tumor-infiltrating macrophages by Christofides, Anthos, Strauss, Laura, Yeo, Alan, Cao, Carol, Charest, Alain, Boussiotis, Vassiliki A.

    Published in Nature immunology (01-08-2022)
    “…Long recognized as an evolutionarily ancient cell type involved in tissue homeostasis and immune defense against pathogens, macrophages are being re-discovered…”
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  18. 18

    The Frequency and Suppressor Function of CD4+CD25highFoxp3+ T Cells in the Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck by STRAUSS, Laura, BERGMANN, Christoph, GOODING, William, JOHNSON, Jonas T, WHITESIDE, Theresa L

    Published in Clinical cancer research (01-11-2007)
    “…Objective: Immune escape is a characteristic feature of head and neck squamous cell carcinoma (HNSCC). Regulatory T cells (Treg) might contribute to HNSCC…”
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  19. 19

    A Unique Subset of CD4+CD25highFoxp3+ T Cells Secreting Interleukin-10 and Transforming Growth Factor-β1 Mediates Suppression in the Tumor Microenvironment by STRAUSS, Laura, BERGMANN, Christoph, SZCZEPANSKI, Miroslaw, GOODING, William, JOHNSON, Jonas T, WHITESIDE, Theresa L

    Published in Clinical cancer research (01-08-2007)
    “…Purpose: Immunosuppression, including that mediated by CD4 + CD25 high Foxp3 + regulatory T cells (Treg), is a characteristic feature of head and neck squamous…”
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  20. 20

    Implications of metabolism-driven myeloid dysfunctions in cancer therapy by Strauss, Laura, Guarneri, Valentina, Gennari, Alessandra, Sica, Antonio

    Published in Cellular & molecular immunology (01-04-2021)
    “…Immune homeostasis is maintained by an adequate balance of myeloid and lymphoid responses. In chronic inflammatory states, including cancer, this balance is…”
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