Search Results - "Strauss, Juliane"

Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting by Alkan, H. Furkan, Walter, Katharina E., Luengo, Alba, Madreiter-Sokolowski, Corina T., Stryeck, Sarah, Lau, Allison N., Al-Zoughbi, Wael, Lewis, Caroline A., Thomas, Craig J., Hoefler, Gerald, Graier, Wolfgang F., Madl, Tobias, Vander Heiden, Matthew G., Bogner-Strauss, Juliane G.

“…Mitochondrial function is important for aspartate biosynthesis in proliferating cells. Here, we show that mitochondrial aspartate export via the…”
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A 24‐base pair deletion in the ABO gene causes a hereditary splice site defect: a novel mechanism underlying ABO blood group O by Matzhold, Eva Maria, Drexler, Camilla, Wagner, Andrea, Bernecker, Claudia, Pessentheiner, Ariane, Bogner‐Strauß, Juliane Gertrude, Helmberg, Wolfgang, Wagner, Thomas

“…BACKGROUND Blood group A and B antigens are synthesized by glycosyltransferases regulated by a complex molecular genetic background. A multibase deletion in…”
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Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis by Prokesch, Andreas, Graef, Franziska A., Madl, Tobias, Kahlhofer, Jennifer, Heidenreich, Steffi, Schumann, Anne, Moyschewitz, Elisabeth, Pristoynik, Petra, Blaschitz, Astrid, Knauer, Miriam, Muenzner, Matthias, Bogner‐Strauss, Juliane G., Dohr, Gottfried, Schulz, Tim J., Schupp, Michael

“…ABSTRACT The ability to adapt cellular metabolism to nutrient availability is critical for survival. The liver plays a central role in the adaptation to…”
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LincRNA-Cox2 Promotes Late Inflammatory Gene Transcription in Macrophages through Modulating SWI/SNF-Mediated Chromatin Remodeling by Hu, Guoku, Gong, Ai-Yu, Wang, Yang, Ma, Shibin, Chen, Xiqiang, Chen, Jing, Su, Chun-Jen, Shibata, Annemarie, Strauss-Soukup, Juliane K, Drescher, Kristen M, Chen, Xian-Ming

“…Long intergenic noncoding RNAs (lincRNAs) are long noncoding transcripts (>200 nt) from the intergenic regions of annotated protein-coding genes. One of the…”
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A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice by Oh, Da Young, Walenta, Evelyn, Akiyama, Taro E, Lagakos, William S, Lackey, Denise, Pessentheiner, Ariane R, Sasik, Roman, Hah, Nasun, Chi, Tyler J, Cox, Jason M, Powels, Mary Ann, Di Salvo, Jerry, Sinz, Christopher, Watkins, Steven M, Armando, Aaron M, Chung, Heekyung, Evans, Ronald M, Quehenberger, Oswald, McNelis, Joanne, Bogner-Strauss, Juliane G, Olefsky, Jerrold M

“…An orally available, highly selective agonist of Gpr120 is developed and tested. It is well known that the ω–3 fatty acids (ω–3-FAs; also known as n –3 fatty…”
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Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice by Morinaga, Hidetaka, Mayoral, Rafael, Heinrichsdorff, Jan, Osborn, Olivia, Franck, Niclas, Hah, Nasun, Walenta, Evelyn, Bandyopadhyay, Gautam, Pessentheiner, Ariane R, Chi, Tyler J, Chung, Heekyung, Bogner-Strauss, Juliane G, Evans, Ronald M, Olefsky, Jerrold M, Oh, Da Young

“…The current dogma is that obesity-associated hepatic inflammation is due to increased Kupffer cell (KC) activation. However, recruited hepatic macrophages…”
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Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome by Lass, Achim, Zimmermann, Robert, Haemmerle, Guenter, Riederer, Monika, Schoiswohl, Gabriele, Schweiger, Martina, Kienesberger, Petra, Strauss, Juliane G., Gorkiewicz, Gregor, Zechner, Rudolf

“…Adipose triglyceride lipase (ATGL) was recently identified as an important triacylglycerol (TG) hydrolase promoting the catabolism of stored fat in adipose and…”
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N -Acetylaspartate Metabolism Outside the Brain: Lipogenesis, Histone Acetylation, and Cancer by Bogner-Strauss, Juliane G

“…-acetylaspartate (NAA) is a highly abundant brain metabolite. Aberrant NAA concentrations have been detected in many pathological conditions and although the…”
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Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase by Zimmermann, R, Strauss, J.G, Haemmerle, G, Schosiwohl, G, Birner-Gruenberger, R, Riederer, M, Lass, A, Neuberger, G, Eisenhaber, F, Hermetter, A

“…Mobilization of fatty acids from triglyceride stores in adipose tissue requires lipolytic enzymes. Dysfunctional lipolysis affects energy homeostasis and may…”
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Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation by Trefely, Sophie, Huber, Katharina, Liu, Joyce, Noji, Michael, Stransky, Stephanie, Singh, Jay, Doan, Mary T., Lovell, Claudia D., von Krusenstiern, Eliana, Jiang, Helen, Bostwick, Anna, Pepper, Hannah L., Izzo, Luke, Zhao, Steven, Xu, Jimmy P., Bedi, Kenneth C., Rame, J. Eduardo, Bogner-Strauss, Juliane G., Mesaros, Clementina, Sidoli, Simone, Wellen, Kathryn E., Snyder, Nathaniel W.

“…Quantitative subcellular metabolomic measurements can explain the roles of metabolites in cellular processes but are subject to multiple confounding factors…”
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Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues by Schupp, Michael, Chen, Fang, Briggs, Erika R, Rao, Shilpa, Pelzmann, Helmut J, Pessentheiner, Ariane R, Bogner-Strauss, Juliane G, Lazar, Mitchell A, Baldwin, Don, Prokesch, Andreas

“…Fasting induces specific molecular and metabolic adaptions in most organisms. In biomedical research fasting is used in metabolic studies to synchronize…”
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A host cell long noncoding RNA NR_033736 regulates type I interferon-mediated gene transcription and modulates intestinal epithelial anti-Cryptosporidium defense by Li, Juan, Jin, Kehua, Li, Min, Mathy, Nicholas W, Gong, Ai-Yu, Deng, Silu, Martins, Gislaine A, Sun, Mingfei, Strauss-Soukup, Juliane K, Chen, Xian-Ming

“…The gastrointestinal epithelium guides the immune system to differentiate between commensal and pathogenic microbiota, which relies on intimate links with the…”
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RalA controls glucose homeostasis by regulating glucose uptake in brown fat by Skorobogatko, Yuliya, Dragan, Morgan, Cordon, Claudia, Reilly, Shannon M., Hung, Chao-Wei, Xia, Wenmin, Zhao, Peng, Wallace, Martina, Lackey, Denise E., Chen, Xiao-Wei, 陈晓伟, Osborn, Olivia, Bogner-Strauss, Juliane G., Theodorescu, Dan, Metallo, Christian M., Olefsky, Jerrold M., Saltiel, Alan R.

“…Insulin increases glucose uptake into adipose tissue and muscle by increasing trafficking of the glucose transporter Glut4. In cultured adipocytes, the…”
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N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes by Huber, Katharina, Hofer, Dina C., Trefely, Sophie, Pelzmann, Helmut J., Madreiter-Sokolowski, Corina, Duta-Mare, Madalina, Schlager, Stefanie, Trausinger, Gert, Stryeck, Sarah, Graier, Wolfgang F., Kolb, Dagmar, Magnes, Christoph, Snyder, Nathaniel W., Prokesch, Andreas, Kratky, Dagmar, Madl, Tobias, Wellen, Kathryn E., Bogner-Strauss, Juliane G.

“…The discovery of significant amounts of metabolically active brown adipose tissue (BAT) in adult humans renders it a promising target for anti-obesity…”
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Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling by Obrowsky, Sascha, Chandak, Prakash G., Patankar, Jay V., Povoden, Silvia, Schlager, Stefanie, Kershaw, Erin E., Bogner-Strauss, Juliane G., Hoefler, Gerald, Levak-Frank, Sanja, Kratky, Dagmar

“…Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme mediating triglyceride (TG) hydrolysis. The lack of ATGL results in TG accumulation in multiple…”
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Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses by Deng, Silu, He, Wei, Gong, Ai-Yu, Li, Min, Wang, Yang, Xia, Zijie, Zhang, Xin-Tiang, Huang Pacheco, Andrew S., Naqib, Ankur, Jenkins, Mark, Swanson, Patrick C., Drescher, Kristen M., Strauss-Soukup, Juliane K., Belshan, Michael, Chen, Xian-Ming

“…Cryptosporidium infects gastrointestinal epithelium and is a leading cause of infectious diarrhea and diarrheal-related death in children worldwide. There are…”
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APMAP interacts with lysyl oxidase–like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion by Pessentheiner, Ariane R., Huber, Katharina, Pelzmann, Helmut J., Prokesch, Andreas, Radner, Franz P. W., Wolinski, Heimo, Lindroos‐Christensen, Josefine, Hoefler, Gerald, Rülicke, Thomas, Birner‐Gruenberger, Ruth, Bilban, Martin, Bogner‐Strauss, Juliane G.

“…ABSTRACT Adipocyte plasma membrane–associated protein (APMAP) has been described as an adipogenic factor in 3T3‐L1 cells with unknown biochemical function; we…”
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MicroRNA-30c promotes human adipocyte differentiation and co-represses PAI-1 and ALK2 by Karbiener, Michael, Neuhold, Claudia, Opriessnig, Peter, Prokesch, Andreas, Bogner-Strauss, Juliane G., Scheideler, Marcel

“…Obesity is characterized by excessive adipose tissue mass and associated with type 2 diabetes and cardiovascular diseases. To fight obesity and its sequels,…”
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Delivery of parasite Cdg7_Flc_0990 RNA transcript into intestinal epithelial cells during Cryptosporidium parvum infection suppresses host cell gene transcription through epigenetic mechanisms by Wang, Yang, Gong, Ai‐Yu, Ma, Shibin, Chen, Xiqiang, Strauss‐Soukup, Juliane K., Chen, Xian‐Ming

“…Summary Cryptosporidial infection causes dysregulated transcription of host genes key to intestinal epithelial homeostasis, but the underlying mechanisms…”
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Oxidized phospholipids on alkyl-amide scaffold demonstrate anti-endotoxin and endothelial barrier-protective properties by Oskolkova, Olga V., Hodzic, Alma, Karki, Pratap, Gesslbauer, Bernd, Ke, Yunbo, Hofer, Dina C., Bogner-Strauss, Juliane G., Galano, Jean-Marie, Oger, Camille, Birukova, Anna, Durand, Thierry, Birukov, Konstantin, Bochkov, Valery

“…Oxidized phospholipids (OxPLs) containing enzymatically or non-enzymatically oxidized fatty acids (oxylipins) are increasingly recognized as lipid mediators…”
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