Search Results - "Straub, R"

Multi-OMICS study of a CHCHD10 variant causing ALS demonstrates metabolic rewiring and activation of endoplasmic reticulum and mitochondrial unfolded protein responses by Straub, Isabella R, Weraarpachai, Woranontee, Shoubridge, Eric A

“…Abstract Mutations in CHCHD10, coding for a mitochondrial intermembrane space protein, are a rare cause of autosomal dominant amyotrophic lateral sclerosis…”
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Energy regulation and neuroendocrine–immune control in chronic inflammatory diseases by Straub, R. H., Cutolo, M., Buttgereit, F., Pongratz, G.

“…  Straub RH, Cutolo M, Buttgereit F, Pongratz G (University Hospital Regensburg, Regensburg, Germany; University of Genova, Genova, Italy; and Charité…”
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Organocatalytic Kinetic Resolution of N‑Boc-Isoxazolidine-5-ones by Straub, Matthew R, Birman, Vladimir B

“…Easily accessible racemic N-Boc-isoxazolidine-5-ones undergo enantioselective alcoholysis promoted by double hydrogen bond donor amine organocatalysts,…”
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Achilles tendinosis is associated with sprouting of substance P positive nerve fibres by Schubert, T E O, Weidler, C, Lerch, K, Hofstädter, F, Straub, R H

“…Objectives: To identify and characterise nerve fibres and inflammatory alterations in painful Achilles tendinosis and thus gain evidence about the origin of…”
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Anti-inflammatory mechanisms of methotrexate in rheumatoid arthritis by CUTOLO, M, SULLI, A, PIZZORNI, C, SERIOLO, B, STRAUB, R H

“…90 However, this in vitro study and another more recent in vivo study both showed that the coadministration of MTX and folic acid reduces the cellular uptake…”
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GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium by Trampush, J W, Yang, M L Z, Yu, J, Knowles, E, Davies, G, Liewald, D C, Starr, J M, Djurovic, S, Melle, I, Sundet, K, Christoforou, A, Reinvang, I, DeRosse, P, Lundervold, A J, Steen, V M, Espeseth, T, Räikkönen, K, Widen, E, Palotie, A, Eriksson, J G, Giegling, I, Konte, B, Roussos, P, Giakoumaki, S, Burdick, K E, Payton, A, Ollier, W, Horan, M, Chiba-Falek, O, Attix, D K, Need, A C, Cirulli, E T, Voineskos, A N, Stefanis, N C, Avramopoulos, D, Hatzimanolis, A, Arking, D E, Smyrnis, N, Bilder, R M, Freimer, N A, Cannon, T D, London, E, Poldrack, R A, Sabb, F W, Congdon, E, Conley, E D, Scult, M A, Dickinson, D, Straub, R E, Donohoe, G, Morris, D, Corvin, A, Gill, M, Hariri, A R, Weinberger, D R, Pendleton, N, Bitsios, P, Rujescu, D, Lahti, J, Le Hellard, S, Keller, M C, Andreassen, O A, Deary, I J, Glahn, D C, Malhotra, A K, Lencz, T

“…The complex nature of human cognition has resulted in cognitive genomics lagging behind many other fields in terms of gene discovery using genome-wide…”
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Communicating intent to develop shared situation awareness and engender trust in human-agent teams by Schaefer, Kristin E., Straub, Edward R., Chen, Jessie Y.C., Putney, Joe, Evans, A.W.

“…This paper addresses issues related to integrating autonomy-enabled, intelligent agents into collaborative, human-machine teams. Interaction with intelligent…”
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Increased Serum Levels of soluble ST2 as a Predictor of Disease Progression in Systemic Sclerosis by Günther, F, Straub, RH, Hartung, W, Luchner, A, Fleck, M, Ehrenstein, B

“…Interleukin-33 (IL-33) has been investigated as a mediator in the pathogenesis of fibrosis in lung, liver, and heart. There is accumulating evidence for the…”
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The role of affective control, strategy repertoire and subjective emotion regulation success in developmental internalising psychopathology by Herber, Carolin C. L. M., Lott-Sandkamp, Lea L., Straub, Elisa R., Tuschen-Caffier, Brunna

“…Adolescence poses significant challenges for emotion regulation (ER) and is thus a critical phase in the emergence of various mental disorders, specifically…”
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Serious obstetric complications interact with hypoxia-regulated vascular-expression genes to influence schizophrenia risk by Nicodemus, K K, Marenco, S, Batten, A J, Vakkalanka, R, Egan, M F, Straub, R E, Weinberger, D R

“…The etiology of schizophrenia is thought to include both epistasis and gene-environment interactions. We sought to test whether a set of schizophrenia…”
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It takes two to Tango: Automated vehicles and human beings do the dance of driving – Four social considerations for policy by Straub, Edward R., Schaefer, Kristin E.

“…Automated vehicle (AV) policy development and assessment is a difficult and complicated process. Today’s road and vehicle policies are the product of a hundred…”
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Adrenal Insufficiency and Colonic Inflammation after a Novel Chronic Psycho-Social Stress Paradigm in Mice: Implications and Mechanisms by Reber, S. O, Birkeneder, L, Veenema, A. H, Obermeier, F, Falk, W, Straub, R. H, Neumann, I. D

“…We investigated chronic psycho-social stress effects on stress-related parameters and on pathohistological changes in the murine colon. Moreover, we aimed to…”
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Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation by Rösch, G., El Bagdadi, K., Muschter, D., Taheri, S., Dorn, C., Meurer, A., Straub, R.H., Zaucke, F., Schilling, A.F., Grässel, S., Jenei-Lanzl, Z.

“…Osteoarthritis (OA) pathogenesis involves the interaction of articular cartilage with surrounding tissues, which are innervated by tyrosine…”
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Anti-inflammatory role of sympathetic nerves in chronic intestinal inflammation by Straub, R H, Grum, F, Strauch, U, Capellino, S, Bataille, F, Bleich, A, Falk, W, Schölmerich, J, Obermeier, F

“…Substance P (SP) is a pro-inflammatory neuropeptide in colitis, whereas sympathetic neurotransmitters are anti-inflammatory at high concentrations. In all…”
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Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia by HASHIMOTO, R, STRAUB, R. E, WEICKERT, C. S, HYDE, T. M, KLEINMAN, J. E, WEINBERGER, D. R

“…Genetic linkage and association have implicated neuregulin-1 (NRG-1) as a schizophrenia susceptibility gene. We measured mRNA expression levels of the three…”
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Chronic Intermittent Psychosocial Stress (Social Defeat/Overcrowding) in Mice Increases the Severity of an Acute DSS-Induced Colitis and Impairs Regeneration by Reber, S. O, Obermeier, F, Straub, H. R, Falk, W, Neumann, I. D

“…Ulcerative colitis is a multifactorial disease, with immunological, genetic, and environmental factors playing an important role in its pathogenesis. Here we…”
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Systemic metabolic signaling in acute and chronic gastrointestinal inflammation of inflammatory bowel diseases by Karrasch, T, Obermeier, F, Straub, R H

“…Acute and chronic intestinal inflammation stimulates innate and adaptive immune systems, thereby increasing energy demand of activated immune cells. Energy…”
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Allelic variation in GAD1 (GAD ) is associated with schizophrenia and influences cortical function and gene expression by STRAUB, R. E, LIPSKA, B. K, EGAN, M. F, GOLDBERG, T. E, CALLICOTT, J. H, MAYHEW, M. B, VAKKALANKA, R. K, KOLACHANA, B. S, KLEINMAN, J. E, WEINBERGER, D. R

“…Cortical GABAergic dysfunction has been implicated as a key component of the pathophysiology of schizophrenia and decreased expression of the…”
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Variables affecting the risk of pneumothorax and intrapulmonal hemorrhage in CT-guided transthoracic biopsy by Khan, M. F., Straub, R., Moghaddam, S. R., Maataoui, A., Gurung, J., Wagner, T. O. F., Ackermann, H., Thalhammer, A., Vogl, T. J., Jacobi, V.

“…The influence of various variables on the rate of pneumothorax and intrapulmonal hemorrhage associated with computed tomography (CT)-guided transthoracic…”
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The role of the sympathetic nervous system in intestinal inflammation by Straub, R H, Wiest, R, Strauch, U G, Härle, P, Schölmerich, J

“…The nervous system in the intestine controls motility, secretion, sensory perception, and immune function. Peptidergic neurones with neurotransmitters such as…”
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