Search Results - "Straub, Kenneth"

Structure of the Unphosphorylated STAT5a Dimer by Neculai, Dante, Neculai, Ana Mirela, Verrier, Sophie, Straub, Kenneth, Klumpp, Klaus, Pfitzner, Edith, Becker, Stefan

“…STAT proteins have the function of signaling from the cell membrane into the nucleus, where they regulate gene transcription. Latent mammalian STAT proteins…”
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Application of zwitterionic detergents to the solubilization of integral membrane proteins for two-dimensional gel electrophoresis and mass spectrometry by Henningsen, Robert, Gale, Brenda L., Straub, Kenneth M., DeNagel, Diane C.

“…Comparative analysis has long been utilized in biological research to interpret protein interactions in both drug naïve versus drug challenged and normal…”
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Identification of a Specific Methionine in Mammalian 15-Lipoxygenase Which Is Oxygenated by the Enzyme Product 13-HPODE: Dissociation of Sulfoxide Formation from Self-Inactivation by Gan, Qing-Fen, Witkop, Gregory L, Sloane, David L, Straub, Kenneth M, Sigal, Elliott

“…Mammalian 15-lipoxygenases undergo a characteristic self-inactivation. The oxygenation of a single methionine to methionine sulfoxide, by…”
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Secondary ion mass spectrometry with cesium ion primary beam and liquid target matrix for analysis of bioorganic compounds by Aberth, William, Straub, Kenneth M, Burlingame, A. L

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The Glutamine Hydrolysis Function of Human GMP Synthetase by Nakamura, John, Straub, Kenneth, Wu, John, Lou, Lillian

“…GMP synthetase (EC 6.3.5.2) is an amidotransferase that catalyzes the amination of xanthosine 5′-monophosphate to form GMP in the presence of glutamine and…”
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Rapid structure elucidation of catecholamine conjugates with tandem mass spectrometry by Rudewicz, Patrick, Straub, Kenneth M

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Isolation and characterization of pyrimidine-psoralen-pyrimidine photodiadducts from DNA by Kanne, David, Straub, Kenneth, Hearst, John E, Rapoport, Henry

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Characterization of hapten binding to immunoconjugates by electrospray ionization mass spectrometry by Straub, Kenneth M, Levy, Mark J

“…Electrospray ionization mass spectrometry (ESI-MS) has been used to characterize the covalent binding of different haptens to the enzyme glucose 6-phosphate…”
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Isolation and characterization of pyrimidine-psoralen photoadducts from DNA by Straub, Kenneth, Kanne, David, Hearst, John E, Rapoport, Henry

“…The authors have examined the photoadducts of 4'-hydroxymethyl-4,5',8-trimethylpsoralen (HMT) and native DNA. Five nucleoside--HMT monoaddition products have…”
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High-performance liquid chromatographic (HPLC) and HPLC-mass spectrometric (MS) analysis of the degradation of the luteinizing hormone-releasing hormone (LH-RH) antagonist RS-26306 in aqueous solution by Strickley, R G, Brandl, M, Chan, K W, Straub, K, Gu, L

“…The kinetics of the degradation of an LH-RH antagonist, RS-26306,1, in aqueous solution from pH 1 to pH 11 were studied by reverse-phase HPLC. The pH-rate…”
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Arachidonic and eicosapentaenoic acid metabolism in bovine neutrophils and platelets: effect of calcium ionophore by Taylor, S M, Laegreid, W W, Heidel, J R, Straub, K M, Liggitt, H D, Silflow, R M, Breeze, R G, Leid, R W

“…Substitution of dietary fatty acids has potential for altering the inflammatory response. The purpose of the present study was to define the metabolites of…”
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Trapping of an IMP Dehydrogenase−Substrate Covalent Intermediate by Mycophenolic Acid by Link, John O, Straub, Kenneth

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The psoralen-DNA photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5',8-trimethylpsoralen by Kanne, David, Straub, Kenneth, Rapoport, Henry, Hearst, John E

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The glutamine hydrolysis function of human GMP synthetase. Identification of an essential active site cysteine by Nakamura, J, Straub, K, Wu, J, Lou, L

“…GMP synthetase (EC 6.3.5.2) is an amidotransferase that catalyzes the amination of xanthosine 5'-monophosphate to form GMP in the presence of glutamine and…”
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Probing the Active Site of Human IMP Dehydrogenase Using Halogenated Purine Riboside 5'-Monophosphates and Covalent Modification Reagents by Antonino, Lisa C, Straub, Kenneth, Wu, John C

“…Active-site amino acid residues of human type II inosine 5'-monophosphate dehydrogenase (IMPDH) were investigated using the covalent modification reagents…”
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Rationally Designed Inhibitors of Inosine Monophosphate Dehydrogenase by Zhang, Han-Zhong, Rao, Kotesvar, Carr, Stephen F, Papp, Eva, Straub, Kenneth, Wu, John C, Fried, Josef

“…Functionalized 2-alkyl derivatives of inosinic acid have been synthesized to serve as reversible as well as irreversible inhibitors of the human type II enzyme…”
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Psoralen-Deoxyribonucleic Acid Photoreaction. Characterization of the Monoaddition Products From 8-Methoxypsoralen and 4,5',8-Trimethylpsoralen by Kanne, D, Straub, K, Rapoport, H, Hearst, JE

“…The isolation and structural characterization are described of the major monoaddition products formed in the photoreaction of two naturally occurring…”
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The reaction of the psoralens with deoxyribonucleic acid by Hearst, J E, Isaacs, S T, Kanne, D, Rapoport, H, Straub, K

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Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation by Romano, M C, Straub, K M, Yodis, L A, Eckardt, R D, Newton, J F

“…An assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection, has been developed. Conditions were…”
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Metabolism of leukotriene B4 in hepatic microsomes by Newton, J F, Eckardt, R, Bender, P E, Leonard, T, Straub, K

“…Leukotriene B4 was metabolized in rat hepatic microsomes to two products. Mass spectral analysis of these two metabolites indicated that the major metabolite…”
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