Search Results - "Strasser, K"

Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect by Johnson, Kaitlyn E, Howard, Grant, Mo, William, Strasser, Michael K, Lima, Ernesto A B F, Huang, Sui, Brock, Amy

“…Most models of cancer cell population expansion assume exponential growth kinetics at low cell densities, with deviations to account for observed slowing of…”
Get full text

Increasing Neural Stem Cell Division Asymmetry and Quiescence Are Predicted to Contribute to the Age-Related Decline in Neurogenesis by Bast, Lisa, Calzolari, Filippo, Strasser, Michael K., Hasenauer, Jan, Theis, Fabian J., Ninkovic, Jovica, Marr, Carsten

“…Adult murine neural stem cells (NSCs) generate neurons in drastically declining numbers with age. How cellular dynamics sustain neurogenesis and how…”
Get full text

The gold-standard genome of Aspergillus niger NRRL 3 enables a detailed view of the diversity of sugar catabolism in fungi by Aguilar-Pontes, M.V., Brandl, J., McDonnell, E., Strasser, K., Nguyen, T.T.M., Riley, R., Mondo, S., Salamov, A., Nybo, J.L., Vesth, T.C., Grigoriev, I.V., Andersen, M.R., Tsang, A., de Vries, R.P.

“…The fungal kingdom is too large to be discovered exclusively by classical genetics. The access to omics data opens a new opportunity to study the diversity…”
Get full text

Lineage marker synchrony in hematopoietic genealogies refutes the PU.1/GATA1 toggle switch paradigm by Strasser, Michael K., Hoppe, Philipp S., Loeffler, Dirk, Kokkaliaris, Konstantinos D., Schroeder, Timm, Theis, Fabian J., Marr, Carsten

“…Molecular regulation of cell fate decisions underlies health and disease. To identify molecules that are active or regulated during a decision, and not before…”
Get full text

Aromatase Inhibitors in the Treatment and Prevention of Breast Cancer by GOSS, Paul E, STRASSER, Kathrin

“…The purpose of this article is to provide an overview of the current clinical status and possible future applications of aromatase inhibitors in breast cancer…”
Get full text

278 In vitro activation of tumor-infiltrating lymphocytes by Strasser, K, Sachet, M, Birnleitner, H, Stift, J, Bergmann, M, Oehler, R

Get full text

PO-380 Regulatory T cells encounter pro-inflammatory immune cells in human colorectal cancer by Strasser, K, Birnleitner, H, Beer, A, Sachet, M, Bergmann, M, Oehler, R

“…IntroductionThe normal colon is facing a load of microbes, which requires a constant immunosuppression to avoid exaggerated immune responses. The immunological…”
Get full text

Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios by Hoppe, Philipp S., Schwarzfischer, Michael, Loeffler, Dirk, Kokkaliaris, Konstantinos D., Hilsenbeck, Oliver, Moritz, Nadine, Endele, Max, Filipczyk, Adam, Gambardella, Adriana, Ahmed, Nouraiz, Etzrodt, Martin, Coutu, Daniel L., Rieger, Michael A., Marr, Carsten, Strasser, Michael K., Schauberger, Bernhard, Burtscher, Ingo, Ermakova, Olga, Bürger, Antje, Lickert, Heiko, Nerlov, Claus, Theis, Fabian J., Schroeder, Timm

“…Live imaging and single-cell analyses are used to show that decision-making by differentiating haematopoietic stem cells between the megakaryocytic–erythroid…”
Get full text

314 Hyperoxia Changes the Balance of the Thioredoxin/Peroxiredoxin System in the Neonatal Rat Brain by Strasser, K, Bendix, I, Weichelt, U, Endesfelder, S, Haefen, C von, Heumann, R, Ehrkamp, A, Buehrer, C, Felderhoff-Mueser, U, Sifringer, M

“…Background and Aim As demonstrated previously, oxygen contributes to the pathogenesis of neonatal brain damage and leading to neurocognitive impairment of…”
Get full text

Host selection of the symbiotic copepod Clausidium dissimile in two sympatric populations of ghost shrimp by CORSETTI, J. L, STRASSER, K. M

“…Ghost shrimp, Lepidophthalmus louisianensis and Sergio trilobata are 2 common burrowing decapod crustaceans in Tampa Bay, Florida, which affect the benthic…”
Get full text

Single-cell gene set scoring with nearest neighbor graph smoothed data (gssnng) by Gibbs, David L, Strasser, Michael K, Huang, Sui

“…Abstract Summary Gene set scoring (or enrichment) is a common dimension reduction task in bioinformatics that can be focused on the differences between groups…”
Get full text

Mex67p Mediates Nuclear Export of a Variety of RNA Polymerase II Transcripts by Hurt, Ed, Sträßer, Katja, Segref, Alexandra, Bailer, Susanne, Schlaich, Nick, Presutti, Carlo, Tollervey, David, Jansen, Ralf

“…Mex67p is essential for nuclear poly(A)+ RNA export in yeast, but which specific transcripts are transported by Mex67p is not known. We observed that…”
Get full text

cgCorrect: a method to correct for confounding cell-cell variation due to cell growth in single-cell transcriptomics by Blasi, Thomas, Buettner, Florian, Strasser, Michael K, Marr, Carsten, Theis, Fabian J

“…Accessing gene expression at a single-cell level has unraveled often large heterogeneity among seemingly homogeneous cells, which remains obscured when using…”
Get more information

Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p by Hurt, Ed, Sträßer, Katja

“…The yeast nuclear protein Yra1p is an essential export factor for mRNA. Yra1p interacts directly with the mRNA transport factor Mex67p/Mtr2p, which is…”
Get full text

Thalidomide treatment in multiple myeloma by Strasser, Kathrin, Ludwig, Heinz

“…Thalidomide was first evaluated in patients with refractory multiple myeloma in the mid-90s. Based on the promising results achieved in these patients, the…”
Get full text

High-resolution ultrasonography of the carpal tunnel by Buchberger, W, Schön, G, Strasser, K, Jungwirth, W

“…Twenty-eight wrists of 25 patients with carpal tunnel syndrome (CTS) and 28 wrists of 14 normal control subjects were studied with high-frequency real-time…”
Get more information

Settlement cues in an Atlantic coast population of the ghost shrimp Callichirus major (Crustacea: Decapoda: Thalassinidea) by Strasser, K. M., Felder, D. L.

“…Larvae of Callichirus major (Say) were first given stimuli upon reaching the last zoeal stage (ZIV), decapodid stage (D), or first juvenile stage (J1). Animals…”
Get full text

Outcomes in women with invasive ductal or invasive lobular early stage breast cancer treated with anastrozole or exemestane in CCTG (NCIC CTG) MA.27 by Strasser-Weippl, K., Sudan, G., Ramjeesingh, R., Shepherd, L.E., O'Shaughnessy, J., Parulekar, W.R., Liedke, P.E.R., Chen, B.E., Goss, P.E.

“…Histological subtype, (invasive ductal breast cancer (IDBC)/invasive lobular breast cancer (ILBC)), might be a marker for differential response to endocrine…”
Get full text

Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export by Sträßer, Katja, Hurt, Ed

“…Mex67p and Mtr2p constitute an essential mRNA export complex that interacts with poly(A)+ RNA and nuclear pore proteins. We have identified Yra1p, an…”
Get full text

Changes in lung parenchyma after acute respiratory distress syndrome (ARDS): assessment with high-resolution computed tomography by Nöbauer-Huhmann, I M, Eibenberger, K, Schaefer-Prokop, C, Steltzer, H, Schlick, W, Strasser, K, Fridrich, P, Herold, C J

“…The aim of this study was to evaluate the appearance, extent, and distribution of parenchymal changes in the lung after acute respiratory distress syndrome…”
Get full text