Search Results - "Strasser, Jane E"

Shiga Toxin Subtypes Display Dramatic Differences in Potency by Fuller, Cynthia A, Pellino, Christine A, Flagler, Michael J, Strasser, Jane E, Weiss, Alison A

“…Purified Shiga toxin (Stx) alone is capable of producing systemic complications, including hemolytic-uremic syndrome (HUS), in animal models of disease. Stx…”
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Luminal-applied flagellin is internalized by polarized intestinal epithelial cells and elicits immune responses via the TLR5 dependent mechanism by Eaves-Pyles, Tonyia, Bu, Heng-Fu, Tan, Xiao-di, Cong, Yingzi, Patel, Jignesh, Davey, Robert A, Strasser, Jane E

“…Bacteria release flagellin that elicits innate responses via Toll-like receptor 5 (TLR5). Here, we investigated the fate of apically administrated full length…”
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Clearance of Herpes Simplex Virus Type 2 by CD8+ T Cells Requires Gamma Interferon and either Perforin- or Fas-Mediated Cytolytic Mechanisms by DOBBS, Melanie E, STRASSER, Jane E, CHU, Chin-Fun, CHALK, Claudia, MILLIGAN, Gregg N

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Nonpathogenic Escherichia coli Can Contribute to the Production of Shiga Toxin by GAMAGE, Shantini D, STRASSER, Jane E, CHALK, Claudia L, WEISS, Alison A

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Commensal Bacteria Influence Escherichia coli O157:H7 Persistence and Shiga Toxin Production in the Mouse Intestine by Gamage, Shantini D, Patton, Angela K, Strasser, Jane E, Chalk, Claudia L, Weiss, Alison A

“…The presence of commensal flora reduced colonization of Escherichia coli O157:H7 and production of Shiga toxin (Stx) in the murine intestine. Stx production…”
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Comparative Analysis of the Abilities of Shiga Toxins 1 and 2 To Bind to and Influence Neutrophil Apoptosis by Flagler, Michael J, Strasser, Jane E, Chalk, Claudia L, Weiss, Alison A

“…Hemolytic-uremic syndrome (HUS), the life-threatening complication following infection by the intestinal pathogen Escherichia coli O157:H7, is due to the…”
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Potent Adjuvant Activity of Cationic Liposome-DNA Complexes for Genital Herpes Vaccines by Bernstein, David I, Cardin, Rhonda D, Bravo, Fernando J, Strasser, Jane E, Farley, Nicholas, Chalk, Claudia, Lay, Marla, Fairman, Jeff

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Regulation of the Macrophage Vacuolar ATPase and Phagosome-Lysosome Fusion by Histoplasma capsulatum by Strasser, Jane E, Newman, Simon L, Ciraolo, Georgianne M, Morris, Randal E, Howell, Michael L, Dean, Gary E

“…Histoplasma capsulatum (Hc) maintains a phagosomal pH of about 6.5. This strategy allows Hc to obtain iron from transferrin, and minimize the activity of…”
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Evaluating Various Areas of Process Improvement in an Effort to Improve Clinical Research: Discussions from the 2012 Clinical Translational Science Award (CTSA) Clinical Research Management Workshop by Strasser, Jane E., Cola, Philip A., Rosenblum, Daniel

“…Emphasis has been placed on assessing the efficiency of clinical and translational research as part of the National Institutes of Health (NIH) goal to “improve…”
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Ohio CTSAs Implement a Reliant IRB Model for Investigator‐Initiated Multicenter Clinical Trials by Cola, Philip A., Reider, Carson, Strasser, Jane E.

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Antibody-mediated protection against genital herpes simplex virus type 2 disease in mice by Fc gamma receptor-dependent and -independent mechanisms by Chu, Chin-Fun, Meador, Michael G, Young, Christal G, Strasser, Jane E, Bourne, Nigel, Milligan, Gregg N

“…Abstract The ability of antibody (Ab) to modulate HSV pathogenesis is well recognized but the mechanisms by which HSV-specific IgG antibodies protect against…”
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A soluble divalent class I MHC/IgG1 fusion protein activates CD8+ T cells in vivo by CAREY, Brenna, DELAY, Monica, STRASSER, Jane E, CHALK, Claudia, DUDLEY-MCCLAIN, Kristen, MILLIGAN, Gregg N, BRUNNER, Hermine I, THOMTON, Sherry, HIRSCH, Raphael

“…CD8+ T lymphocytes recognize tumor and viral antigens bound to class I major histocompatibility complexes (MHC). Tumors and viruses may evade detection by…”
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Secretagogue-triggered transfer of membrane proteins from neuroendocrine secretory granules to synaptic-like microvesicles by Strasser, J E, Arribas, M, Blagoveshchenskaya, A D, Cutler, D F

“…The membrane proteins of all regulated secretory organelles (RSOs) recycle after exocytosis. However, the recycling of those membrane proteins that are…”
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Cloning and functional expression of a tetrabenazine sensitive vesicular monoamine transporter from bovine chromaffin granules by Howell, Mike, Shirvan, Anat, Stern-Bach, Yael, Steiner-Mordoch, Sonia, Strasser, Jane E., Dean, Gary E., Schuldiner, Shimon

“…Using oligonucleotide primers derived from the vesicular monoamine transporters sequences, a cDNA predicted to encode the bovine chromaffin granule amine…”
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Factors That Affect Integrity of Authorship of Scientific Meeting Abstracts by Lynch, John, Strasser, Jane E., Lindsell, Christopher J., Tsevat, Joel

“…Background: Strict criteria for article authorship exist to guide decisions on who should be considered an author. Less is known about how authorship for…”
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Clearance of Herpes Simplex Virus Type 2 by CD8 super(+) T Cells Requires Gamma Interferon and either Perforin- or Fas-Mediated Cytolytic Mechanisms by Dobbs, Melanie E, Strasser, Jane E, Chu, Chin-Fun, Chalk, Claudia, Milligan, Gregg N

“…The T-cell-mediated resolution of herpes simplex virus type 2 (HSV-2) genital infections is not fully understood. In these studies, the mechanisms by which CD8…”
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A soluble divalent class I MHC/IgG 1 fusion protein activates CD8+ T cells in vivo by Carey, Brenna, DeLay, Monica, Strasser, Jane E., Chalk, Claudia, Dudley-McClain, Kristen, Milligan, Gregg N., Brunner, Hermine I., Thornton, Sherry, Hirsch, Raphael

“…CD8+ T lymphocytes recognize tumor and viral antigens bound to class I major histocompatibility complexes (MHC). Tumors and viruses may evade detection by…”
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Synaptotagmin I-ΔC2B. A novel synaptotagmin isoform with a single C2 domain in the bovine adrenal medulla by Hewitt, Eric W., Tao, Jing-Xian, Strasser, Jane E., Cutler, Daniel F., Dean, Gary E.

“…Synaptotagmin I is a 65 kDa type 1 membrane glycoprotein found in secretory organelles that plays a key role in regulated exocytosis. We have characterised two…”
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Synaptotagmin I-DeltaC2B. A novel synaptotagmin isoform with a single C2 domain in the bovine adrenal medulla by Hewitt, Eric W, Tao, Jing-Xian, Strasser, Jane E, Cutler, Daniel F, Dean, Gary E

“…Synaptotagmin I is a 65 kDa type 1 membrane glycoprotein found in secretory organelles that plays a key role in regulated exocytosis. We have characterised two…”
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The vacuolar ATPase and phagocytosis by Strasser, Jane E

“…The structure and function of the vacuolar ATPase remains largely uncharacterized. In this work I used antisense technology specifically to manipulate the…”
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