Search Results - "Strasser, Geraldine"

Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching by Strasser, Geraldine A., Kaminker, Joshua S., Tessier-Lavigne, Marc

“…The development of the vertebrate vascular system is mediated by both genetic patterning of vessels and by angiogenic sprouting in response to hypoxia. Both of…”
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VEGF Mediates Commissural Axon Chemoattraction through Its Receptor Flk1 by Ruiz de Almodovar, Carmen, Fabre, Pierre J., Knevels, Ellen, Coulon, Cathy, Segura, Inmaculada, Haddick, Patrick C.G., Aerts, Liesbeth, Delattin, Nicolas, Strasser, Geraldine, Oh, Won-Jong, Lange, Christian, Vinckier, Stefan, Haigh, Jody, Fouquet, Coralie, Gu, Chengua, Alitalo, Kari, Castellani, Valerie, Tessier-Lavigne, Marc, Chedotal, Alain, Charron, Frederic, Carmeliet, Peter

“…Growing axons are guided to their targets by attractive and repulsive cues. In the developing spinal cord, Netrin-1 and Shh guide commissural axons toward the…”
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Critical Role of Ena/VASP Proteins for Filopodia Formation in Neurons and in Function Downstream of Netrin-1 by Lebrand, Cecile, Dent, Erik W, Strasser, Geraldine A, Lanier, Lorene M, Krause, Matthias, Svitkina, Tatyana M, Borisy, Gary G, Gertler, Frank B

“…Ena/VASP proteins play important roles in axon outgrowth and guidance. Ena/VASP activity regulates the assembly and geometry of actin networks within…”
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Lamellipodin, an Ena/VASP Ligand, Is Implicated in the Regulation of Lamellipodial Dynamics by Krause, Matthias, Leslie, Jonathan D., Stewart, Mary, Lafuente, Esther M., Valderrama, Ferran, Jagannathan, Radhika, Strasser, Geraldine A., Rubinson, Douglas A., Liu, Hui, Way, Michael, Yaffe, Michael B., Boussiotis, Vassiliki A., Gertler, Frank B.

“…Lamellipodial protrusion is regulated by Ena/VASP proteins. We identified Lamellipodin (Lpd) as an Ena/VASP binding protein. Both proteins colocalize at the…”
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Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways by Lo, Bryan, Strasser, Geraldine, Sagolla, Meredith, Austin, Cary D, Junttila, Melissa, Mellman, Ira

“…The tumor suppressor Lkb1/STK11/Par-4 is a key regulator of cellular energy, proliferation, and polarity, yet its mechanisms of action remain poorly defined…”
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The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network by Bladt, Friedhelm, Aippersbach, Elke, Gelkop, Sigal, Strasser, Geraldine A., Nash, Piers, Tafuri, Anna, Gertler, Frank B., Pawson, Tony

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Arp2/3 Is a Negative Regulator of Growth Cone Translocation by Strasser, Geraldine A, Rahim, Nazimah Abdul, VanderWaal, Kristyn E, Gertler, Frank B, Lanier, Lorene M

“…Arp2/3 is an actin binding complex that is enriched in the peripheral lamellipodia of fibroblasts, where it forms a network of short, branched actin filaments,…”
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Antagonism between Ena/VASP Proteins and Actin Filament Capping Regulates Fibroblast Motility by Bear, James E., Svitkina, Tatyana M., Krause, Matthias, Schafer, Dorothy A., Loureiro, Joseph J., Strasser, Geraldine A., Maly, Ivan V., Chaga, Oleg Y., Cooper, John A., Borisy, Gary G., Gertler, Frank B.

“…Cell motility requires lamellipodial protrusion, a process driven by actin polymerization. Ena/VASP proteins accumulate in protruding lamellipodia and promote…”
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A Dysfunctional Desmin Mutation in a Patient with Severe Generalized Myopathy by Munoz-Marmol, Ana M., Strasser, Geraldine, Isamat, Marcos, Coulombe, Pierre A., Yang, Yanmin, Roca, Xavier, Vela, Elena, Mate, Jose L., Coll, Jaume, Fernandez-Figueras, Maria Teresa, Navas-Palacios, Jose J., Ariza, Aurelio, Fuchs, Elaine

“…Mice lacking desmin produce muscle fibers with Z disks and normal sarcomeric organization. However, the muscles are mechanically fragile and degenerate upon…”
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Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation by Guttman, Ofer, Le Thomas, Adrien, Marsters, Scot, Lawrence, David A, Gutgesell, Lauren, Zuazo-Gaztelu, Iratxe, Harnoss, Jonathan M, Haag, Simone M, Murthy, Aditya, Strasser, Geraldine, Modrusan, Zora, Wu, Thomas, Mellman, Ira, Ashkenazi, Avi

“…Dendritic cells (DCs) promote adaptive immunity by cross-presenting antigen-based epitopes to CD8+ T cells. DCs process internalized protein antigens into…”
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VEGF Mediates Commissural Axon Chemoattraction through Its Receptor Flk1 by Ruiz de Almodovar, Carmen, Fabre, Pierre J., Knevels, Ellen, Coulon, Cathy, Segura, Inmaculada, Haddick, Patrick C.G., Aerts, Liesbeth, Delattin, Nicolas, Strasser, Geraldine, Oh, Won-Jong, Lange, Christian, Vinckier, Stefan, Haigh, Jody, Fouquet, Coralie, Gu, Chengua, Alitalo, Kari, Castellani, Valerie, Tessier-Lavigne, Marc, Chedotal, Alain, Charron, Frederic, Carmeliet, Peter

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Abstract PD14-03: Molecular mechanism of ipatasertib (IPAT) and its combination with atezolizumab (atezo) in patients (pts) with locally advanced/metastatic triple-negative breast cancer (aTNBC) by Schmid, Peter, Loirat, Delphine, Savas, Peter, Espinosa, Enrique, Boni, Valentina, Italiano, Antoine, White, Shane, Laliman, Victor, Strasser, Geraldine, Lin, Kui, Cheng, Karen, Mani, Aruna, Wongchenko, Matthew, Sablin, Marie-Paule, Shah, Kalpit

“…Abstract Background: Phase 3 trials (IMpassion130, KEYNOTE-355) have shown improved efficacy with the addition of immune checkpoint modulators to chemotherapy…”
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Abstract A41: Inhibition of Lkb1 in cultured embryonic pancreas destabilizes tissue architecture to generate precancerous-like lesions by Lo, Bryan, Viotti, Manuel, Strasser, Geraldine, Mellman, Ira

“…Abstract The tumor suppressor Lkb1 is a regulator of cellular energy, proliferation, and polarity, yet the mechanism by which it controls tissue morphogenesis…”
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Integrators of the Cytoskeleton that Stabilize Microtubules by Yang, Yanmin, Bauer, Christoph, Strasser, Geraldine, Wollman, Robert, Julien, Jean-Pierre, Fuchs, Elaine

“…Sensory neurodegeneration occurs in mice defective in BPAG1, a gene encoding cytoskeletal linker proteins capable of anchoring neuronal intermediate filaments…”
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Corticosterone selectively increases follicle-stimulating hormone beta-subunit messenger ribonucleic acid in primary anterior pituitary cell culture without affecting its half-life by Kilen, S M, Szabo, M, Strasser, G A, McAndrews, J M, Ringstrom, S J, Schwartz, N B

“…We demonstrated previously that glucocorticoids differentially affect the levels of the two pituitary gonadotropins, LH and FSH, both in vivo and in vitro. In…”
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