Search Results - "Strasburger, Christian"
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A Consensus Statement on acromegaly therapeutic outcomes
Published in Nature reviews. Endocrinology (01-09-2018)“…The 11th Acromegaly Consensus Conference in April 2017 was convened to update recommendations on therapeutic outcomes for patients with acromegaly. Consensus…”
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Efficacy and Safety of Pegvisomant in the Treatment of Acromegaly
Published in Archives of medical research (01-12-2023)“…Pegvisomant, the first and currently only clinically available growth hormone receptor antagonist, is an effective therapeutic option for the medical treatment…”
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A Pituitary Society update to acromegaly management guidelines
Published in Pituitary (01-02-2021)“…Guidelines and consensus statements ensure that physicians managing acromegaly patients have access to current information on evidence-based treatments to…”
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A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update
Published in The journal of clinical endocrinology and metabolism (01-04-2020)“…Abstract Objective The aim of the Acromegaly Consensus Group was to revise and update the consensus on diagnosis and treatment of acromegaly comorbidities last…”
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Biochemical investigations in diagnosis and follow up of acromegaly
Published in Pituitary (01-02-2017)“…Measurements of human growth hormone (GH) and insulin-like growth-factor I (IGF-I) are cornerstones in the diagnosis of acromegaly. Both hormones are also used…”
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Multidisciplinary management of acromegaly: A consensus
Published in Reviews in endocrine & metabolic disorders (01-12-2020)“…The 13th Acromegaly Consensus Conference was held in November 2019 in Fort Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and…”
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Expert consensus document: A consensus on the medical treatment of acromegaly
Published in Nature reviews. Endocrinology (01-04-2014)“…Acromegaly usually occurs owing to a growth-hormone-secreting adenoma in the pituitary gland, which leads to metabolic and anatomical changes in the patient…”
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Maintenance of Acromegaly Control in Patients Switching From Injectable Somatostatin Receptor Ligands to Oral Octreotide
Published in The journal of clinical endocrinology and metabolism (01-10-2020)“…Abstract Purpose The phase 3 CHIASMA OPTIMAL trial (NCT03252353) evaluated efficacy and safety of oral octreotide capsules (OOCs) in patients with acromegaly…”
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Investigating significant health trends in growth hormone treatments registry: rationale, aims and design of a nationwide prospective registry (study protocol)
Published in Orphanet journal of rare diseases (10-05-2023)“…Somatropin treatment is indicated in a variety of disorders including growth hormone (GH) deficiency, Prader-Willi and Turner syndrome, chronic renal…”
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Short stature explained by dimerization of human growth hormone induced by a p.C53S point mutation
Published in The Journal of biological chemistry (10-04-2020)“…A homozygous mutation in growth hormone 1 (GH1) was recently identified in an individual with growth failure. This mutation, c.705G>C, causes replacement of…”
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Glucocorticoids in elite sport: current status, controversies and innovative management strategies-a narrative review
Published in British journal of sports medicine (01-01-2020)“…The use of systemic glucocorticoids (GCs), as well as local injections, continues to be a controversial issue in the sport/anti-doping community. There is…”
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MPOWERED Trial Open-Label Extension: Long-term Efficacy and Safety Data for Oral Octreotide Capsules in Acromegaly
Published in The journal of clinical endocrinology and metabolism (17-11-2023)“…Abstract Context The MPOWERED core trial (NCT02685709) and open-label extension (OLE) phase investigated long-term efficacy and safety of oral octreotide…”
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Health-Related Quality of Life in Adult Patients with Craniopharyngioma
Published in World neurosurgery (01-10-2021)“…Craniopharyngiomas (CPs) are benign, dysontogenetic tumors associated with complex endocrinologic and neurologic symptoms and high morbidity. The aim of this…”
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Macimorelin as a Diagnostic Test for Adult GH Deficiency
Published in The journal of clinical endocrinology and metabolism (01-08-2018)“…Abstract Purpose The diagnosis of adult GH deficiency (AGHD) is challenging and often requires confirmation with a GH stimulation test (GHST). The insulin…”
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Corticotroph tumor progression after bilateral adrenalectomy: data from ERCUSYN
Published in Endocrine-related cancer (01-12-2022)“…Corticotroph tumor progression after bilateral adrenalectomy/Nelson’s syndrome (CTP-BADX/NS) is a severe complication of bilateral adrenalectomy (BADX). The…”
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The European Registry on Cushing's syndrome: 2-year experience. Baseline demographic and clinical characteristics
Published in European journal of endocrinology (01-09-2011)“…ObjectiveThe European Registry on Cushing's syndrome (ERCUSYN) is designed to collect prospective and follow-up data at EU level on Cushing's syndrome…”
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Long-term treatment with pegvisomant: observations from 2090 acromegaly patients in ACROSTUDY
Published in European journal of endocrinology (01-12-2018)“…Objectives ACROSTUDY is an international, non-interventional study of acromegaly patients treated with pegvisomant (PEGV), a growth hormone receptor antagonist…”
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Sunitinib in Refractory Adrenocortical Carcinoma: A Phase II, Single-Arm, Open-Label Trial
Published in The journal of clinical endocrinology and metabolism (01-10-2012)“…Context: Treatment of refractory adrenocortical carcinoma (ACC) is not established. Animal experiments pointed toward adrenal toxicity of sunitinib. Objective:…”
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Efficacy of Temozolomide Therapy in Patients With Aggressive Pituitary Adenomas and Carcinomas—A German Survey
Published in The journal of clinical endocrinology and metabolism (01-03-2020)“…Abstract Context Despite growing evidence that temozolomide (TMZ) therapy is effective for the treatment of aggressive pituitary tumors (APTs) or carcinomas…”
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Increasing frequency of combination medical therapy in the treatment of acromegaly with the GH receptor antagonist pegvisomant
Published in European journal of endocrinology (01-04-2018)“…Pegvisomant monotherapy is effective and safe in treatment of acromegaly. However, some clinicians combine pegvisomant with somatostatin analogues (SSA) or…”
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