Search Results - "Strange, Keehn"
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Abstract LB-C04: Phosphoproteomics unravels dynamic regulation of energy sensor by CDK5 in Neuroendocrine Tumor
Published in Molecular cancer therapeutics (01-12-2019)“…Background: Pheochromocytoma (PC) is a rare Neuroendocrine (NE) tumor usually originates from adrenal gland’s chromaffin cells. These tumors are often benign…”
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Understanding the Molecular Underpinnings of Neuronal Kinase CDK5 mediated Metabolic Vulnerabilities in Neuroendocrine Tumors
Published in The FASEB journal (01-04-2020)“…Abstract only…”
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Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer
Published in Cell reports (Cambridge) (16-08-2022)“…Metabolic dysfunction mutations can impair energy sensing and cause cancer. Loss of function of the mitochondrial tricarboxylic acid (TCA) cycle enzyme subunit…”
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