Search Results - "Strange, Daniel P"
-
1
Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells
Published in mBio (16-07-2019)“…Zika virus (ZIKV) is unique among mosquito-borne flaviviruses in its ability to be sexually transmitted. Persistent ZIKV infection in the testes, which are…”
Get full text
Journal Article -
2
RIG-I and MDA5 are modulated by bone morphogenetic protein (BMP6) and are essential for restricting Zika virus infection in human Sertoli cells
Published in Frontiers in microbiology (12-01-2023)“…Sexual transmission of Zika virus (ZIKV) is associated with virus persistence in the testes and shedding in the seminal fluid for months after recovery. We…”
Get full text
Journal Article -
3
In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury
Published in PLoS pathogens (18-05-2023)“…The hallmark of severe COVID-19 involves systemic cytokine storm and multi-organ injury including testicular inflammation, reduced testosterone, and germ cell…”
Get full text
Journal Article -
4
Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4
Published in Frontiers in microbiology (17-08-2017)“…Ebola virus (EBOV), a member of the family, causes the most severe form of viral hemorrhagic fever. Although no FDA licensed vaccine or treatment against Ebola…”
Get full text
Journal Article -
5
Paracrine IFN Response Limits ZIKV Infection in Human Sertoli Cells
Published in Frontiers in microbiology (17-05-2021)“…Zika virus (ZIKV) is unique among mosquito-borne flaviviruses in its ability to be sexually transmitted. The testes have been implicated as sites of long-term…”
Get full text
Journal Article -
6
Zika Virus Infects Human Sertoli Cells and Modulates the Integrity of the In Vitro Blood-Testis Barrier Model
Published in Journal of virology (15-11-2017)“…Confirmed reports of Zika virus (ZIKV) in human seminal fluid for months after the clearance of viremia suggest the ability of ZIKV to establish persistent…”
Get full text
Journal Article -
7
Immunoprofiles of human Sertoli cells infected with Zika virus reveals unique insights into host-pathogen crosstalk
Published in Scientific reports (07-06-2018)“…Confirmed reports of Zika virus (ZIKV) in seminal fluid months after clearance of viremia suggests that ZIKV can establish persistent infection in the…”
Get full text
Journal Article -
8
Human testicular organoid system as a novel tool to study Zika virus pathogenesis
Published in Emerging microbes & infections (09-05-2018)Get full text
Journal Article -
9
Axl promotes ZIKV entry and modulates antiviral state of human Sertoli cells
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Zika virus (ZIKV) is unique among mosquito-borne flaviviruses in its ability to be sexually transmitted. The ability of ZIKV to establish persistent…”
Get full text
Journal Article -
10
Investigating the Testicular Tropism of Zika Virus Using 2D and 3D Human Tissue Culture Systems
Published 01-01-2020“…Zika virus (ZIKV) is a mosquito-borne flavivirus traditionally associated with mild febrile illness. However, following the 2015–2016 epidemic in the Americas,…”
Get full text
Dissertation