Search Results - "Strange, Daniel"
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Extracellular-matrix tethering regulates stem-cell fate
Published in Nature materials (01-07-2012)“…To investigate how substrate properties influence stem-cell fate, we cultured single human epidermal stem cells on polydimethylsiloxane (PDMS) and…”
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2
Mechanical behaviour of electrospun fibre-reinforced hydrogels
Published in Journal of materials science. Materials in medicine (01-03-2014)“…Mechanically robust and biomimicking scaffolds are needed for structural engineering of tissues such as the intervertebral disc, which are prone to failure and…”
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3
Zika Virus Infects Human Sertoli Cells and Modulates the Integrity of the In Vitro Blood-Testis Barrier Model
Published in Journal of virology (15-11-2017)“…Confirmed reports of Zika virus (ZIKV) in human seminal fluid for months after the clearance of viremia suggest the ability of ZIKV to establish persistent…”
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4
Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells
Published in mBio (16-07-2019)“…Zika virus (ZIKV) is unique among mosquito-borne flaviviruses in its ability to be sexually transmitted. Persistent ZIKV infection in the testes, which are…”
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In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury
Published in PLoS pathogens (18-05-2023)“…The hallmark of severe COVID-19 involves systemic cytokine storm and multi-organ injury including testicular inflammation, reduced testosterone, and germ cell…”
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6
Separating poroviscoelastic deformation mechanisms in hydrogels
Published in Applied physics letters (21-01-2013)“…Hydrogels have applications in drug delivery, mechanical actuation, and regenerative medicine. When hydrogels are deformed, load-relaxation arising from fluid…”
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Biomimetic bone-like composites fabricated through an automated alternate soaking process
Published in Acta biomaterialia (01-10-2011)“…Hydroxyapatite–gelatin composites have been proposed as suitable scaffolds for bone and dentin tissue regeneration. There is considerable interest in producing…”
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RIG-I and MDA5 are modulated by bone morphogenetic protein (BMP6) and are essential for restricting Zika virus infection in human Sertoli cells
Published in Frontiers in microbiology (12-01-2023)“…Sexual transmission of Zika virus (ZIKV) is associated with virus persistence in the testes and shedding in the seminal fluid for months after recovery. We…”
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Composite hydrogels for nucleus pulposus tissue engineering
Published in Journal of the mechanical behavior of biomedical materials (01-07-2012)“…Tissue engineering offers a paradigm shift in the treatment of back pain. Engineered intervertebral discs could replace degenerated tissue and overcome the…”
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10
Size effects in indentation of hydrated biological tissues
Published in Journal of materials research (14-01-2012)“…Fluid flow in biological tissues is important in both mechanical and biological contexts. Given the hierarchical nature of tissues, there are varying length…”
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Immunoprofiles of human Sertoli cells infected with Zika virus reveals unique insights into host-pathogen crosstalk
Published in Scientific reports (07-06-2018)“…Confirmed reports of Zika virus (ZIKV) in seminal fluid months after clearance of viremia suggests that ZIKV can establish persistent infection in the…”
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12
Human testicular organoid system as a novel tool to study Zika virus pathogenesis
Published in Emerging microbes & infections (09-05-2018)Get full text
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13
Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4
Published in Frontiers in microbiology (17-08-2017)“…Ebola virus (EBOV), a member of the family, causes the most severe form of viral hemorrhagic fever. Although no FDA licensed vaccine or treatment against Ebola…”
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14
Paracrine IFN Response Limits ZIKV Infection in Human Sertoli Cells
Published in Frontiers in microbiology (17-05-2021)“…Zika virus (ZIKV) is unique among mosquito-borne flaviviruses in its ability to be sexually transmitted. The testes have been implicated as sites of long-term…”
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15
Biomimetic calcium carbonate–gelatin composites as a model system for eggshell mineralization
Published in Journal of materials research (28-12-2012)“…The composite nature of mineralized natural materials is achieved through both the microstructural inclusion of an organic component and an overall…”
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Extracellular-matrix tethering regulates stem-cell fate
Published in Nature materials (01-08-2012)Get full text
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17
Restoration of compressive loading properties of lumbar discs with a nucleus implant—a finite element analysis study
Published in The spine journal (01-07-2010)“…Abstract Background Context Discectomy is a common procedure for treating sciatica. However, both the operation and preceding herniated disc alter the…”
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18
Tracing oncogene-driven remodelling of the intestinal stem cell niche
Published in Nature (London) (17-06-2021)“…Interactions between tumour cells and the surrounding microenvironment contribute to tumour progression, metastasis and recurrence 1 – 3 . Although mosaic…”
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The Price of Internal Consistency?
Published in Tyndale bulletin (1966) (01-05-2000)“…Clark Pinnock has attempted to reconcile divine sovereignty with human freedom by suggesting that any future based on human decisions is logically unknowable…”
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Zika virus infects human Sertoli cells and trespass the blood-testes barrier to migrate across the seminiferous epithelium
Published in The Journal of immunology (1950) (01-05-2017)“…The 2015–2016 epidemic of Zika virus (ZIKV) has identified sexual transmission as a new route of disease spread. Presence of ZIKV in the semen when viremia is…”
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