Search Results - "Strand, Douglas"

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    Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity by Shao, Mengle, Hepler, Chelsea, Zhang, Qianbin, Shan, Bo, Vishvanath, Lavanya, Henry, Gervaise H., Zhao, Shangang, An, Yu A., Wu, Yibo, Strand, Douglas W., Gupta, Rana K.

    Published in Cell stem cell (01-04-2021)
    “…Adipose precursor cells (APCs) exhibit regional variation in response to obesity, for unclear reasons. Here, we reveal that HIFα-induced PDGFRβ signaling…”
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    Journal Article
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    Cancer associated fibroblasts in cancer pathogenesis by Franco, Omar E., Shaw, Aubie K., Strand, Douglas W., Hayward, Simon W.

    Published in Seminars in cell & developmental biology (01-02-2010)
    “…In the past century, gradual but sustained advances in our understanding of the molecular mechanisms involved in the growth and invasive properties of cancer…”
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    Identification and characterization of cellular heterogeneity within the developing renal interstitium by England, Alicia R, Chaney, Christopher P, Das, Amrita, Patel, Mohita, Malewska, Alicia, Armendariz, Daniel, Hon, Gary C, Strand, Douglas W, Drake, Keri A, Carroll, Thomas J

    Published in Development (Cambridge) (14-08-2020)
    “…Kidney formation requires the coordinated growth of multiple cell types including the collecting ducts, nephrons, vasculature and interstitium. There is a…”
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    Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice by Hepler, Chelsea, Shan, Bo, Zhang, Qianbin, Henry, Gervaise H, Shao, Mengle, Vishvanath, Lavanya, Ghaben, Alexandra L, Mobley, Angela B, Strand, Douglas, Hon, Gary C, Gupta, Rana K

    Published in eLife (28-09-2018)
    “…White adipose tissue (WAT) remodeling is dictated by coordinated interactions between adipocytes and resident stromal-vascular cells; however, the functional…”
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    Single‐cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions by Joseph, Diya B, Henry, Gervaise H, Malewska, Alicia, Reese, Jeffrey C, Mauck, Ryan J, Gahan, Jeffrey C, Hutchinson, Ryan C, Malladi, Venkat S, Roehrborn, Claus G, Vezina, Chad M, Strand, Douglas W

    Published in The Journal of pathology (01-10-2021)
    “…Stromal–epithelial interactions are critical to the morphogenesis, differentiation, and homeostasis of the prostate, but the molecular identity and anatomy of…”
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    Design and validation of a high-speed hyperspectral laparoscopic imaging system by Pruitt, Kelden, Ma, Ling, Rathgeb, Armand, Gahan, Jeffrey C, Johnson, Brett A, Strand, Douglas W, Fei, Baowei

    Published in Journal of biomedical optics (01-09-2024)
    “…Minimally invasive surgery (MIS) has shown vast improvement over open surgery by reducing post-operative stays, intraoperative blood loss, and infection rates…”
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    A multi-omic investigation of male lower urinary tract symptoms: Potential role for JC virus by Thomas, Samuel, Dunn, Christopher D, Campbell, Lewis J, Strand, Douglas W, Vezina, Chad M, Bjorling, Dale E, Penniston, Kristina L, Li, Lingjun, Ricke, William A, Goldberg, Tony L

    Published in PloS one (25-02-2021)
    “…Male lower urinary tract symptoms (LUTS) comprise a common syndrome of aging that negatively impacts quality of life. The etiology of LUTS is multifactorial,…”
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    Progenitors in prostate development and disease by Joseph, Diya B., Turco, Anne E., Vezina, Chad M., Strand, Douglas W.

    Published in Developmental biology (01-05-2021)
    “…The prostate develops by epithelial budding and branching processes that occur during fetal and postnatal stages. The adult prostate demonstrates remarkable…”
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    5‐Alpha reductase inhibitors induce a prostate luminal to club cell transition in human benign prostatic hyperplasia by Joseph, Diya B, Henry, Gervaise H, Malewska, Alicia, Reese, Jeffrey C, Mauck, Ryan J, Gahan, Jeffrey C, Hutchinson, Ryan C, Mohler, James L, Roehrborn, Claus G, Strand, Douglas W

    Published in The Journal of pathology (01-04-2022)
    “…Benign prostatic hyperplasia (BPH) is a progressive expansion of peri‐urethral prostate tissue common in aging men. Patients with enlarged prostates are…”
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    A Review of Prostate Organogenesis and a Role for iPSC-Derived Prostate Organoids to Study Prostate Development and Disease by Buskin, Adriana, Singh, Parmveer, Lorenz, Oliver, Robson, Craig, Strand, Douglas W, Heer, Rakesh

    “…The prostate is vulnerable to two major age-associated diseases, cancer and benign enlargement, which account for significant morbidity and mortality for men…”
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    Targeting phenotypic heterogeneity in benign prostatic hyperplasia by Strand, Douglas W., Costa, Daniel N., Francis, Franto, Ricke, William A., Roehrborn, Claus G.

    Published in Differentiation (London) (01-07-2017)
    “…Benign prostatic hyperplasia and associated lower urinary tract symptoms remain difficult to treat medically, resulting in hundreds of thousands of surgeries…”
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    Single-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma by Klein, Jason C., Wang, Lei, Strand, Douglas, Lastufka, Chewlan, Hosler, Gregory A., Hon, Gary C.

    Published in Molecular cancer (15-11-2024)
    “…Undifferentiated pleomorphic sarcoma (UPS) and related tumors are the most common type of soft tissue sarcoma. However, this spectrum of tumors has different…”
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    The many ways to make a luminal cell and a prostate cancer cell by Strand, Douglas W, Goldstein, Andrew S

    Published in Endocrine-related cancer (01-12-2015)
    “…Research in the area of stem/progenitor cells has led to the identification of multiple stem-like cell populations implicated in prostate homeostasis and…”
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