Search Results - "Stram, Amanda R"

Progressive mitochondrial protein lysine acetylation and heart failure in a model of Friedreich's ataxia cardiomyopathy by Stram, Amanda R, Wagner, Gregory R, Fogler, Brian D, Pride, P Melanie, Hirschey, Matthew D, Payne, R Mark

“…The childhood heart disease of Friedreich's Ataxia (FRDA) is characterized by hypertrophy and failure. It is caused by loss of frataxin (FXN), a mitochondrial…”
Get full text

Post-translational modifications in mitochondria: protein signaling in the powerhouse by Stram, Amanda R., Payne, R. Mark

“…There is an intimate interplay between cellular metabolism and the pathophysiology of disease. Mitochondria are essential to maintaining and regulating…”
Get full text

Outcomes following surgery for primary mediastinal nonseminomatous germ cell tumors in the cisplatin era by Kesler, Kenneth A., Stram, Amanda R., Timsina, Lava R., Turrentine, Mark W., Brown, John W., Einhorn, Lawrence H.

“…Treatment of primary mediastinal nonseminomatous germ cell tumors involves cisplatin-based chemotherapy followed by surgery to remove residual disease. We…”
Get full text

Mediastinal Germ Cell Tumors: Updates in Diagnosis and Management by Stram, Amanda R, Kesler, Kenneth A

Get full text

Vasculogenic Mesenchymal Tumor: A Clinicopathologic and Molecular Study of 55 Cases of a Distinctive Neoplasm Originating From Mediastinal Yolk Sac Tumor and an Occasional Precursor to Angiosarcoma by Levy, David R., Agaram, Narasimhan P., Kao, Chia-Sui, Franks, Samuel E., Kesler, Kenneth A., Stram, Amanda R., Einhorn, Lawrence H., Bangs, Charles D., Ulbright, Thomas M.

“…We report 55 postchemotherapy resections of primary nonseminomatous mediastinal germ cell tumors with prominent vasculogenic features showing the formation of…”
Get full text

Ross Procedure: How to Do It and How to Teach It by Herrmann, Jeremy L., Stram, Amanda R., Brown, John W.

“…Prosthesis choice for aortic valve replacement (AVR) in children is frequently compromised by unavailability of prostheses in very small sizes, the lack of…”
Get full text

Mediastinal Germ Cell Tumors by Stram, Amanda R., Kesler, Kenneth A.

“…Primary mediastinal nonseminomatous germ cell tumors represent a rare but important malignancy that occurs in otherwise young and healthy patients. Treatment…”
Get full text

Posttranslational Modifications in Mitochondria: Protein Signaling in the Powerhouse by Stram, Amanda R., Payne, R. Mark

“…There is an intimate interplay between cellular metabolism and the pathophysiology of disease. Mitochondria are essential to maintaining and regulating…”
Get full text

NAD + replacement therapy with nicotinamide riboside does not improve cardiac function in a model of mitochondrial heart disease by Stram, Amanda R., Pride, P. Melanie, Payne, R. Mark

“…Abstract only Rationale Protein lysine acetylation is an important post‐translational modification that regulates cardiac metabolism. Sirtuin 3 (SIRT3) is an…”
Get full text

Abstract 210: Progressive Mitochondrial Protein Acetylation and Microsteatosis is Associated with Diastolic Dysfunction in a Hypertrophic Cardiomyopathy Model by Stram, Amanda R, Wagner, Gregory R, Pride, P M, Payne, R M

“…Abstract only We tested the hypothesis that increased mitochondrial protein acetylation is associated with impaired fatty acid metabolism and diastolic…”
Get full text

Mitochondrial Protein Acetylation and Left Ventricular Function in a Model of Hypertrophic Cardiomyopathy and Heart Failure by Stram, Amanda R

“…Rationale: The childhood heart disease of Friedreich’s Ataxia (FRDA) is characterized by hypertrophy and failure. It is caused by loss of frataxin (FXN), a…”
Get full text