Search Results - "Straka, Robert"

Maximally entangled proton and charged hadron multiplicity in Deep Inelastic Scattering by Hentschinski, Martin, Kutak, Krzysztof, Straka, Robert

“…We study the proposal by Kharzeev–Levin to determine entanglement entropy in Deep Inelastic Scattering (DIS) from parton distribution functions (PDFs) and to…”
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The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin‐Associated Musculoskeletal Symptoms by Cooper‐DeHoff, Rhonda M., Niemi, Mikko, Ramsey, Laura B., Luzum, Jasmine A., Tarkiainen, E. Katriina, Straka, Robert J., Gong, Li, Tuteja, Sony, Wilke, Russell A., Wadelius, Mia, Larson, Eric A., Roden, Dan M., Klein, Teri E., Yee, Sook Wah, Krauss, Ronald M., Turner, Richard M., Palaniappan, Latha, Gaedigk, Andrea, Giacomini, Kathleen M., Caudle, Kelly E., Voora, Deepak

“…Statins reduce cholesterol, prevent cardiovascular disease, and are among the most commonly prescribed medications in the world. Statin‐associated…”
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Hmong microbiome ANd Gout, Obesity, Vitamin C (HMANGO-C): A phase II clinical study protocol by Wen, Ya-Feng, Culhane-Pera, Kathleen A, Pergament, Shannon L, Moua, Yeng, Vue, Bai, Yang, Toua, Lo, Muaj, Sun, Boguang, Knights, Dan, Straka, Robert J

“…Hmong men in Minnesota exhibit a high prevalence of gout and hyperuricemia. Although evidence of vitamin C's effectiveness as a treatment for gout is mixed,…”
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Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting by Trottier, Jocelyn, Białek, Andrzej, Caron, Patrick, Straka, Robert J, Milkiewicz, Piotr, Barbier, Olivier

“…Bile acids are considered as extremely toxic at the high concentrations reached during bile duct obstruction, but each acid displays variable cytotoxic…”
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Development and Validation of the Pharmacological Statin‐Associated Muscle Symptoms Risk Stratification Score Using Electronic Health Record Data by Sun, Boguang, Yew, Pui Ying, Chi, Chih‐Lin, Song, Meijia, Loth, Matt, Liang, Yue, Zhang, Rui, Straka, Robert J.

“…Statin‐associated muscle symptoms (SAMS) can lead to statin nonadherence. This paper aims to develop a pharmacological SAMS risk stratification (PSAMS‐RS)…”
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PharmVar GeneFocus: SLCO1B1 by Ramsey, Laura B., Gong, Li, Lee, Seung‐been, Wagner, Jonathan B., Zhou, Xujia, Sangkuhl, Katrin, Adams, Solomon M., Straka, Robert J., Empey, Philip E., Boone, Erin C., Klein, Teri E., Niemi, Mikko, Gaedigk, Andrea

“…The Pharmacogene Variation Consortium (PharmVar) is now providing star (*) allele nomenclature for the highly polymorphic human SLCO1B1 gene encoding the…”
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Randomised clinical study: oral aspirin 325 mg daily vs placebo alters gut microbial composition and bacterial taxa associated with colorectal cancer risk by Prizment, Anna E., Staley, Christopher, Onyeaghala, Guillaume C., Vivek, Sithara, Thyagarajan, Bharat, Straka, Robert J., Demmer, Ryan T., Knights, Dan, Meyer, Katie A., Shaukat, Aasma, Sadowsky, Michael J., Church, Timothy R.

“…Summary Background Aspirin is associated with decreased risk of colorectal cancer (CRC), potentially by modulating the gut microbiome. Aims To evaluate the…”
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Effect of ginger supplementation on the fecal microbiome in subjects with prior colorectal adenoma by Prakash, Ajay, Rubin, Nathan, Staley, Christopher, Onyeaghala, Guillaume, Wen, Ya-Feng, Shaukat, Aasma, Milne, Ginger, Straka, Robert J., Church, Timothy R., Prizment, Anna

“…Ginger has been associated with a decreased incidence of colorectal cancer (CRC) through reduction in inflammatory pathways and inhibition of tumor growth…”
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Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: A pilot study by Trottier, Jocelyn, Białek, Andrzej, Caron, Patrick, Straka, Robert J, Heathcote, Jenny, Milkiewicz, Piotr, Barbier, Olivier

“…Abstract Background Primary biliary cirrhosis and primary sclerosing cholangitis are two cholestatic diseases characterised by hepatic accumulation of bile…”
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Potential Clinical and Economic Impact of Switching Branded Medications to Generics by Straka, Robert J, Keohane, Denis J, Liu, Larry Z

“…Switching branded to generic medications has become a common cost-containment measure. Although this is an important objective for health care systems…”
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Ethnic and genetic factors in methadone pharmacokinetics: A population pharmacokinetic study by Bart, Gavin, Lenz, Scott, Straka, Robert J, Brundage, Richard C

“…Highlights • Methadone has wide interindividual pharmacokinetics. • Population pharmacokinetics identifies covariates influencing pharmacokinetics. • Hmong…”
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Population pharmacokinetics, pharmacodynamics and pharmacogenetics modelling of oxypurinol in Hmong adults with gout and/or hyperuricemia by Wen, Ya-Feng, Brundage, Richard C, Roman, Youssef M, Culhane-Pera, Kathleen A, Straka, Robert J

“…The aim of this study was to quantify identifiable sources of variability, including key pharmacogenetic variants in oxypurinol pharmacokinetics and their…”
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Pharmacogenomic variabilities in geo-ancestral subpopulations and their clinical implications: Results of collaborations with Hmong in the United States by Sun, Boguang, Wen, Ya-Feng, Culhane-Pera, Kathleen A, Lo, Muaj, Straka, Robert J

“…Underrepresentation of subpopulations within geo-ancestral groups engaged in research can exacerbate health disparities and impair progress toward personalized…”
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The Identification of Novel CYP2D6 Variants in US Hmong: Results From Genome Sequencing and Clinical Genotyping by Wen, Ya Feng, Gaedigk, Andrea, Boone, Erin C, Wang, Wendy Y, Straka, Robert J

“…Hmong individuals represent a unique East Asian subpopulation in whom limited information concerning pharmacogenetic variation exists. The objectives of this…”
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Advancing pharmacogenomic research in US Hmong populations: prevalence of key single nucleotide variations in California Hmong by Sun, Boguang, Thao, Tou, Culhane-Pera, Kathleen, Yang, Eric, Thor, Mai Yang, Yang, Pao, Xiong, Metta, Vang, Zoua, Straka, Robert J

“…In collaboration with the Minnesota Hmong community, we have previously discovered significant differences in allele frequencies for key Single Nucleotide…”
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High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid-Lowering Drugs and Diet Network (GOLDN): an interventional study by Wojczynski, Mary K, Glasser, Stephen P, Oberman, Albert, Kabagambe, Edmond K, Hopkins, Paul N, Tsai, Michael Y, Straka, Robert J, Ordovas, Jose M, Arnett, Donna K

“…Postprandial lipemia (PPL) is likely a risk factor for cardiovascular disease but these changes have not been well described and characterized in a large…”
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Evaluation of Suitability of High-Speed Drag Finishing Machine Prototype Utilization for Workpiece Modification by Vozár, Marek, Pätoprstý, Boris, Vopát, Tomáš, Straka, Róbert, Jurina, František, Šajgalík, Michal

“…The purpose of the experimental results evaluated in this paper is to verify the viability of using a prototype drag finishing machine for the modification of…”
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Gout prevalence in the Hmong: a prime example of health disparity and the role of community-based genetic research by Roman, Youssef M, Lor, Kajua, Xiong, Txia, Culhane-Pera, Kathleen, Straka, Robert J

“…Individuals of distinct Asian backgrounds are commonly aggregated as Asian, which could mask the differences in the etiology and prevalence of health…”
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HLA-B58:01 carrier status of Hmong in Minnesota: first in Hmong genotyping for prevalence of this biomarker of risk for severe cutaneous adverse reactions caused by allopurinol by Peng, Kerui, Bjork, Jonathan, Wen, Ya-Feng, Roman, Youssef M., Culhane-Pera, Kathleen, Lo, May Xia, Gertner, Elie, Straka, Robert J.

“…Allopurinol, a common medication to treat gout, is associated with severe cutaneous adverse reactions, and the occurrence is highly predicted by an…”
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Differences in Predicted Warfarin Dosing Requirements Between Hmong and East Asians Using Genotype‐Based Dosing Algorithms by Sun, Boguang, Wen, Ya‐Feng, Culhane‐Pera, Kathleen A., Lo, Muaj, Xiong, Txia, Lee, Koobmeej, Peng, Kerui, Thyagarajan, Bharat, Bishop, Jeffrey R., Zierhut, Heather, Straka, Robert J.

“…Introduction Warfarin’s narrow therapeutic index and high variability in dosage requirements make dosage selection critical. Genetic factors are known to…”
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