Search Results - "Strahler, J. R."

Identification of Novel Escherichia coli Ribosome-Associated Proteins Using Isobaric Tags and Multidimensional Protein Identification Techniques by JIANG, M, SULLIVAN, S. M, WALKER, A. K, STRAHLER, J. R, ANDREWS, P. C, MADDOCK, J. R

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Identification of a polypeptide associated with the malignant phenotype in acute leukemia by Hanash, S M, Strahler, J R, Kuick, R, Chu, E H, Nichols, D

“…A novel polypeptide, designated p18, was detected in a variety of hematopoietic cells by two-dimensional polyacrylamide gel electrophoresis. Quantitative…”
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Characterization of the gene for a proliferation-related phosphoprotein (oncoprotein 18) expressed in high amounts in acute leukemia by MELHEM, R. F, XIAO-XIANG ZHU, HALIAT, N, STRAHLER, J. R, HANASH, S. M

“…The oncoprotein 18 (Op18) gene encodes a proliferation-related cytosolic phosphoprotein, which is induced in normal lymphocytes following mitogenic…”
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Highly Resolving Two-Dimensional Gels for Protein Sequencing by Hanash, S. M., Strahler, J. R., Neel, J. V., Hailat, N., Melhem, R., Keim, D., Zhu, X. X., Wagner, D., Gage, D. A., Watson, J. T.

“…Two-dimensional (2D) PAGE, using carrier ampholytes for the first-dimension separation, has provided a tool for the simultaneous analysis of cellular proteins…”
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Involvement of OP18 in cell proliferation by Melhem, R F, Strahler, J R, Hailat, N, Zhu, X X, Hanash, S M

“…Op18 is a highly conserved major cytosolic phosphoprotein that is expressed at high levels in acute leukemia and in neuroblastoma. In this study we present…”
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Molecular cloning of a novel human leukemia-associated gene. Evidence of conservation in animal species by XIAO-XIANG ZHU, KOZARSKY, K, STRAHLER, J. R, ECKERSKORN, C, LOTTSPEICH, F, MELHEM, R, LOWE, J, FOX, D. A, HANASH, S. M, ATWEH, G. F

“…We have recently described an 18-kilodalton polypeptide (p18) that is present in much greater abundance in acute leukemic blast cells (myeloid and lymphoid)…”
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Phorbol 12-myristate 13-acetate-induced phosphorylation of Op18 in Jurkat T cells. Identification of phosphorylation sites by matrix-assisted laser desorption ionization mass spectrometry by WANG, Y. K, PAO-CHI LIAO, ALLISON, J, GAGE, D. A, ANDREWS, P. C, LUBMAN, D. M, HANASH, S. M, STRAHLER, J. R

“…Op18 is a widely expressed, cell cycle-regulated, phosphoprotein involved in signal transduction of a variety of stimuli. In actively proliferating Jurkat T…”
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Maturation Stage and Proliferation-Dependent Expression of dUTPase in Human T Cells by Strahler, John R., Zhu, Xiao-Xiang, Hora, Nivedita, Wang, Y. Karen, Andrews, Philip C., Roseman, Nancy A., Neel, James V., Turka, Laurence, Hanash, Samir M.

“…We have developed a database of lymphoid polypeptides detected by two-dimensional polyacrylamide gel electrophoresis to aid in studies of leukemogenesis and of…”
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Data Base Analysis of Protein Expression Patterns During T-Cell Ontogeny and Activation by Hanash, S. M., Strahler, J. R., Chan, Y., Kuick, R., Teichroew, D., Neel, J. V., Hailat, N., Keim, D. R., Gratiot-Deans, J., Ungar, D., Melhem, R., Zhu, X. X., Andrews, P., Lottspeich, F., Eckerskorn, C., Chu, E., Ali, I., Fox, D. A., Richardson, B. C., Turka, L. A.

“…We have developed a data base of lymphoid proteins detectable by two-dimensional polyacrylamide gel electrophoresis. The data base contains two-dimensional…”
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Hsp27 expression in neuroblastoma: correlation with disease stage by Ungar, D R, Hailat, N, Strahler, J R, Kuick, R D, Brodeur, G M, Seeger, R C, Reynolds, C P, Hanash, S M

“…The 27-kd heat shock protein (Hsp27) is differentially expressed in some malignancies, including breast carcinoma, leukemia, and malignant fibrous…”
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Similarity of Spontaneous Germinal and in vitro Somatic Cell Mutation Rates in Humans: Implications for Carcinogenesis and for the Role of Exogenous Factors in "Spontaneous" Germinal Mutagenesis by Kuick, R. D., Neel, J. V., Strahler, J. R., Chu, E. H. Y., Bargal, R., Fox, D. A., Hanash, S. M.

“…The rate of spontaneous mutation resulting in electrophoretic variants per cell generation in a human lymphoblastoid cell line, on the basis of experiments…”
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Diminished phosphorylation of a heat shock protein (HSP 27) in infant acute lymphoblastic leukemia by Strahler, J R, Kuick, R, Hanash, S M

“…We have previously reported lack of expression of a polypeptide designated L3 in infant acute lymphoblastic leukemia (ALL). Expression of L3 occurred…”
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Identification of lamin B and histones as 1,25-dihydroxyvitamin D3-regulated nuclear phosphoproteins in HL-60 cells by MARTELL, R. E, STRAHLER, J. R, SIMPSON, R. U

“…1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3)-induced differentiation of HL-60 leukemia cells is accompanied by a number of cellular changes including regulation of…”
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High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification by HAILAT, N, KEIM, D. R, HANASH, S. M, MELHEM, R. F, XIAO-XIANG ZHU, ECKERSKORN, C, BRODEUR, G. M, REYNOLDS, C. P, SEEGER, R. C, LOTTSPEICH, F, STRAHLER, J. R

“…The gene encoding a novel protein designated nm23-H1, which was recently identified as identical to the A subunit of nucleotide diphosphate kinase from human…”
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Activation of resting peripheral blood lymphocytes through the T cell receptor induces rapid phosphorylation of Op18 by Strahler, JR, Hailat, N, Lamb, BJ, Rogers, KP, Underhill, JA, Melhem, RF, Keim, DR, Zhu, X, Kuick, RD, Fox, DA

“…Op18 is a highly conserved major cytosolic phosphoprotein that has been implicated in signal transduction in a wide variety of cell types. Freshly isolated…”
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Hsp27 is a mediator of sustained smooth muscle contraction in response to bombesin by Bitar, K N, Kaminski, M S, Hailat, N, Cease, K B, Strahler, J R

“…We have identified the low MW 27 kD heat shock protein as a major phosphoprotein constituent of smooth muscle and have investigated its potential role in…”
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Expression of a novel nuclear protein in activated and in tat-I expressing T cells by Bielinska, A, Baier, L, Hailat, N, Strahler, JR, Nabel, GJ, Hanash, S

“…The intracellular events that occur in T lymphoid cells after activation or after infection with HIV-1 are not well defined. In the case of HIV-1 infection, it…”
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A Silent, Neutral Substitution Detected by Reverse-Phase High-Performance Liquid Chromatography: Hemoglobin Beirut by Strahler, John R., Rosenbloom, Barnett B., Hanash, Samir M.

“…A substitution of alanine for valine at position 126 in the β -chain of hemoglobin was discovered in a hematologically normal adult male of Lebanese…”
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Temperature-dependent spot positional variability in two-dimensional polypeptide patterns by Görg, A, Postel, W, Friedrich, C, Kuick, R, Strahler, J R, Hanash, S M

“…The effect of temperature, at which isoelectric focusing with immobilized pH gradients is performed, on spot positions and pattern quality in two-dimensional…”
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Cell cycle progression is associated with distinct patterns of phosphorylation of Op18 by Strahler, J R, Lamb, B J, Ungar, D R, Fox, D A, Hanash, S M

“…Op18 is a highly conserved major cytosolic phosphoprotein which has been implicated in signal transduction in a wide variety of cell types. Freshly isolated…”
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