Search Results - "Strader, Lillian F"

Glyceraldehyde 3-Phosphate Dehydrogenase-S, a Sperm-Specific Glycolytic Enzyme, Is Required for Sperm Motility and Male Fertility by Miki, Kiyoshi, Qu, Weidong, Goulding, Eugenia H., Willis, William D., Bunch, Donna O., Strader, Lillian F., Perreault, Sally D., Eddy, Edward M., O'Brien, Deborah A., Yanagimachi, Ryuzo

“…Although glycolysis is highly conserved, it is remarkable that several unique isozymes in this central metabolic pathway are found in mammalian sperm…”
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Success and failure in human spermatogenesis as revealed by teratozoospermic RNAs by Platts, Adrian E., Dix, David J., Chemes, Hector E., Thompson, Kary E., Goodrich, Robert, Rockett, John C., Rawe, Vanesa Y., Quintana, Silvina, Diamond, Michael P., Strader, Lillian F., Krawetz, Stephen A.

“…We are coming to appreciate that at fertilization human spermatozoa deliver the paternal genome alongside a suite of structures, proteins and RNAs. Although…”
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Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides by Tully, Douglas B., Bao, Wenjun, Goetz, Amber K., Blystone, Chad R., Ren, Hongzu, Schmid, Judith E., Strader, Lillian F., Wood, Carmen R., Best, Deborah S., Narotsky, Michael G., Wolf, Douglas C., Rockett, John C., Dix, David J.

“…Four triazole fungicides were studied using toxicogenomic techniques to identify potential mechanisms of action. Adult male Sprague-Dawley rats were dosed for…”
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The healthy men study: design and recruitment considerations for environmental epidemiologic studies in male reproductive health by Olshan, Andrew F., Ph.D, Perreault, Sally D., Ph.D, Bradley, Lorrie, B.A, Buus, Rebecca M., Ph.D, Strader, Lillian F., B.S, Jeffay, Susan C., B.S, Lansdell, Lyle, M.S, Savitz, David A., Ph.D, Herring, Amy, Ph.D

“…Objective To describe study design, conduct and response, and participant characteristics. Design Prospective cohort study. Setting Participants were male…”
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Episodic ozone exposure in Long-Evans rats has limited effects on cauda sperm motility and non-coding RNA populations by Chorley, Brian N., Klinefelter, Gary R., Nelson, Gail M., Strader, Lillian F., Nguyen, Helen H., Schladweiler, Mette C., Palmer, Grant, Moore, Makala L., Grindstaff, Rachel D., Padgett, William T., Carswell, Gleta K., Fisher, Anna A., Kodavanti, Urmila P., Dye, Janice A., Miller, Colette N.

“…Epidemiological evidence suggests the potential for air pollutants to induce male reproductive toxicity. In experimental studies, exposure to ozone during…”
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Reproductive toxicity of a mixture of regulated drinking-water disinfection by-products in a multigenerational rat bioassay by Narotsky, Michael G, Klinefelter, Gary R, Goldman, Jerome M, DeAngelo, Anthony B, Best, Deborah S, McDonald, Anthony, Strader, Lillian F, Murr, Ashley S, Suarez, Juan D, George, Michael H, Hunter, E Sidney, Simmons, Jane Ellen

“…Trihalomethanes (THMs) and haloacetic acids (HAAs) are regulated disinfection by-products (DBPs); their joint reproductive toxicity in drinking water is…”
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Disruption of Testosterone Homeostasis as a Mode of Action for the Reproductive Toxicity of Triazole Fungicides in the Male Rat by Goetz, Amber K., Ren, Hongzu, Schmid, Judith E., Blystone, Chad R., Thillainadarajah, Inthirany, Best, Deborah S., Nichols, Harriette P., Strader, Lillian F., Wolf, Douglas C., Narotsky, Michael G., Rockett, John C., Dix, David J.

“…Triazole fungicides associated with a range of reported male reproductive effects in experimental animals were selected to assess potential toxic modes of…”
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Novel molecular targets associated with testicular dysgenesis induced by gestational exposure to diethylhexyl phthalate in the rat: a role for estradiol by Klinefelter, Gary R, Laskey, John W, Winnik, Witold M, Suarez, Juan D, Roberts, Naomi L, Strader, Lillian F, Riffle, Brandy W, Veeramachaneni, D N Rao

“…Significant research has been focused on phthalate-induced alterations in male reproductive development. Studies on rodents have prompted the notion that a…”
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Comprehensive Assessment of a Chlorinated Drinking Water Concentrate in a Rat Multigenerational Reproductive Toxicity Study by Narotsky, Michael G, Klinefelter, Gary R, Goldman, Jerome M, Best, Deborah S, McDonald, Anthony, Strader, Lillian F, Suarez, Juan D, Murr, Ashley S, Thillainadarajah, Inthirany, Hunter, E. Sidney, Richardson, Susan D, Speth, Thomas F, Miltner, Richard J, Pressman, Jonathan G, Teuschler, Linda K, Rice, Glenn E, Moser, Virginia C, Luebke, Robert W, Simmons, Jane Ellen

“…Some epidemiological studies report associations between drinking water disinfection byproducts (DBPs) and adverse reproductive/developmental effects, e.g.,…”
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Method to assess component contribution to toxicity of complex mixtures： Assessment of puberty acquisition in rats exposed to disinfection byproducts by Parvez, Shahid, Rice, Glenn E., Teuschler, Linda K., Simmons, Jane Ellen, Speth, Thomas F., Richardson, Susan D., Miltner, Richard J., Hunter, E. Sidney, Pressman, Jonathan G., Strader, Lillian F., Klinefelter, Gary R., Goldman, Jerome M., Narotsky, Michael G.

“…A method based on regression modeling was developed to discern the contribution of component chemicals to the toxicity of highly complex, environmentally…”
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Continuous Exposure to Dibromoacetic Acid Delays Pubertal Development and Compromises Sperm Quality in the Rat by Klinefelter, Gary R., Strader, Lillian F., Suarez, Juan D., Roberts, Naomi L., Goldman, Jerome M., Murr, Ashley S.

“…Previously our work on the haloacid by-products of drinking water disinfection focused on adult exposures. Herein we evaluate the consequence of continuous…”
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Bromochloroacetic Acid Exerts Qualitative Effects on Rat Sperm: Implications for a Novel Biomarker by Klinefelter, Gary R., Strader, Lillian F., Suarez, Juan D., Roberts, Naomi L.

“…Disubstituted haloacid by-products of drinking water disinfection such as dibromoacetic acid and dichloroacetic acid have been shown to perturb spermatogenesis…”
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Fertility of Rat Epididymal Sperm after Chemically and Surgically Induced Sympathectomy by DE G. KEMPINAS, W, SUAREZ, J. D, KLINEFELTER, G. R, ROBERTS, N. L, STRADER, L. F, FERRELL, J, GOLDMAN, J. M, NAROTSKY, M. G, PERREAULT, S. D, EVENSON, D. P, RICKER, D. D

“…Guanethidine, a chemical that selectively blocks sympathetic noradrenergic neurons, was used to investigate the role of sympathetic innervation in the…”
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Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants by Linder, R E, Strader, L F, Slott, V L, Suarez, J D

“…Multiple endpoints of spermatotoxicity in short duration tests (1-5 days exposure; 2.5-week assay interval) were investigated in a number of chemicals reported…”
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Histopathologic changes in the testes of rats exposed to dibromoacetic acid by Linder, Ralph E., Klinefelter, Gary R., Strader, Lillian F., Veeramachaneni, D.N.Rao, Roberts, Naomi L., Suarez, Juan D.

“…The present report details histopathologic changes in the testis and epididymis of rats gavaged daily for 2 to 79 d with a by-product of water disinfection,…”
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Spermatotoxicity of dibromoacetic acid in rats after 14 daily exposures by Linder, R E, Klinefelter, G R, Strader, L F, Suarez, J D, Roberts, N L, Dyer, C J

“…Halogenated acetic acids are major disinfection by-products of water chlorination and ozonation. Limited data in experimental animals indicate that repeated…”
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Comparison of rat epididymal sperm counts by IVOS HTM-IDENT and hemacytometer by Strader, Lillian F., Linder, Ralph E., Perreault, Sally D.

“…Epididymal sperm counts, a common measurement in male reproductive toxicity studies, are routinely determined using a hemacytometer. Recently, computer…”
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Acute and long-term effects of a single dose of the fungicide carbendazim (methyl 2-benzimidazole carbamate) on the male reproductive system in the rat by Nakai, M, Hess, R. A, Moore, B. J, Guttroff, R. F, Strader, L. F, Linder, R. E

“…The effects of carbendazim (methyl 2‐benzimidazole carbamate) on the testis, efferent ductules, and sperm were determined in the adult rat after a single oral…”
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Acute effects and long-term sequelae of 1,3-dinitrobenzene on male reproduction in the rat. II. Quantitative and qualitative histopathology of the testis by Hess, R. A, Linder, R. E, Strader, L. F, Perreault, S. D

“…This study determined the quantitative and qualitative histopathologic effects of a single oral dose of 1,3‐dinitrobenzene (48 mg/kg) on the rat testis from 1…”
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Effect of acute exposure to boric acid on the male reproductive system of the rat by Linder, R E, Strader, L F, Rehnberg, G L

“…Adult male rats were dosed orally on d 0 with 0 or 2000 mg/kg of boric acid and killed on posttreatment d 2, 14, 28, and 57, or dosed with 0, 250, 500, 1000,…”
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