Search Results - "Strømhaug, P E"

Use of glycyl-L-phenylalanine 2-naphthylamide, a lysosome-disrupting cathepsin C substrate, to distinguish between lysosomes and prelysosomal endocytic vacuoles by BERG, T. O, STRØMHAUG, P. E, LØVDAL, T, SEGLEN, P. O, BERG, T

“…Lysosome-disrupting enzyme substrates have been used to distinguish between lysosomal and prelysosomal compartments along the endocytic pathway in isolated rat…”
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Approaching the Molecular Mechanism of Autophagy by Stromhaug, Per E., Klionsky, Daniel J.

“…Autophagy is a complex cellular process that involves dynamic membrane rearrangements under a range of physiological conditions. It is a highly regulated…”
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Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris by Guan, J, Stromhaug, P E, George, M D, Habibzadegah-Tari, P, Bevan, A, Dunn, Jr, W A, Klionsky, D J

“…Eukaryotic cells have the ability to degrade proteins and organelles by selective and nonselective modes of micro- and macroautophagy. In addition, there exist…”
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The Atg1-Atg13 Complex Regulates Atg9 and Atg23 Retrieval Transport from the Pre-Autophagosomal Structure by Reggiori, Fulvio, Tucker, Katherine A., Stromhaug, Per E., Klionsky, Daniel J.

“…To survive extreme environmental conditions, and in response to certain developmental and pathological situations, eukaryotic organisms employ the catabolic…”
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Separation of lysosomes and autophagosomes by means of glycyl-phenylalanine-naphthylamide, a lysosome-disrupting cathepsin-C substrate by BERG, T. O, STRØMHAUG, P. E, BERG, T, SEGLEN, P. O

“…In density-gradient analyses of autophagic vacuoles from isolated rat hepatocytes, autophagosomes could be recognized by the presence of an autophagically…”
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Evidence for acidity of prelysosomal autophagic/endocytic vacuoles (amphisomes) by STRØMHAUG, P. E, SEGLEN, P. O

“…[14C]Lactose electroinjected into isolated rat hepatocytes is normally autophagocytosed, transferred to lysosomes and degraded by lysosomal beta-galactosidase,…”
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Autophagosome-associated variant isoforms of cytosolic enzymes by Fengsrud, M, Raiborg, C, Berg, T O, Strømhaug, P E, Ueno, T, Erichsen, E S, Seglen, P O

“…In a search for autophagosome-associated proteins, two-dimensional gel separations of proteins from purified autophagosomes, postnuclear supernatant, cytosol,…”
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Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation by Kim, John, Huang, Wei-Pang, Stromhaug, Per E, Klionsky, Daniel J

“…Under starvation conditions, the majority of intracellular degradation occurs at the lysosome or vacuole by the autophagy pathway. The cytoplasmic substrates…”
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Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes by Berg, T O, Fengsrud, M, Strømhaug, P E, Berg, T, Seglen, P O

“…Amphisomes, the autophagic vacuoles (AVs) formed upon fusion between autophagosomes and endosomes, have so far only been characterized in indirect, functional…”
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Cvt9/Gsa9 Functions in Sequestering Selective Cytosolic Cargo Destined for the Vacuole by Kim, John, Kamada, Yoshiaki, Stromhaug, Per E., Guan, Ju, Hefner-Gravink, Ann, Baba, Misuzu, Scott, Sidney V., Ohsumi, Yoshinori, Dunn, William A., Klionsky, Daniel J.

“…Three overlapping pathways mediate the transport of cytoplasmic material to the vacuole in Saccharomyces cerevisiae. The cytoplasm to vacuole targeting (Cvt)…”
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The Ccz1-Mon1 Protein Complex Is Required for the Late Step of Multiple Vacuole Delivery Pathways by Wang, Chao-Wen, Stromhaug, Per E., Shima, Jun, Klionsky, Daniel J.

“…Mon1 and Ccz1 were identified from a gene deletion library as mutants defective in the vacuolar import of aminopeptidase I (Ape1) via the cytoplasm to vacuole…”
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Yeast Homotypic Vacuole Fusion Requires the Ccz1-Mon1 Complex during the Tethering/Docking Stage by Wang, Chao-Wen, Stromhaug, Per E., Kauffman, Emily J., Weisman, Lois S., Klionsky, Daniel J.

“…The function of the yeast lysosome/vacuole is critically linked with the morphology of the organelle. Accordingly, highly regulated processes control vacuolar…”
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Inhibition of Autophagic-Lysosomal Delivery and Autophagic Lactolysis by Asparagine by Høyvik, Henrik, Gordon, Paul B., Berg, Trond Olav, Strømhaug, Per Eivind, Seglen, Per O.

“…Overall autophagy was measured in isolated hepatocytes as the sequestration and lysosomal hydrolysis of electroinjected [14C]lactose, using HPLC to separate…”
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Apg2 Is a Novel Protein Required for the Cytoplasm to Vacuole Targeting, Autophagy, and Pexophagy Pathways by Wang, C W, Kim, J, Huang, W P, Abeliovich, H, Stromhaug, P E, Dunn, Jr, W A, Klionsky, D J

“…To survive starvation conditions, eukaryotes have developed an evolutionarily conserved process, termed autophagy, by which the vacuole/lysosome mediates the…”
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Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein by Yuan, W, Stromhaug, P E, Dunn, Jr, W A

“…Cytosolic and peroxisomal enzymes necessary for methanol assimilation are synthesized when Pichia pastoris is grown in methanol. Upon adaptation from methanol…”
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Purification and characterization of autophagosomes from rat hepatocytes by Strømhaug, P E, Berg, T O, Fengsrud, M, Seglen, P O

“…To investigate the properties and intracellular origin of autophagosomes, a procedure for the purification and isolation of these organelles from rat liver has…”
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Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors by Holen, I, Gordon, P B, Strømhaug, P E, Berg, T O, Fengsrud, M, Brech, A, Roos, N, Berg, T, Seglen, P O

“…In isolated rat hepatocytes, a radiolabelled tyramine-cellobiose conjugate of asialo-orosomucoid, 125I-TC-AOM, was rapidly taken up by receptor-mediated…”
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GSA11 Encodes a Unique 208-kDa Protein Required for Pexophagy and Autophagy in Pichia pastoris by Strømhaug, Per E., Bevan, Andrew, Dunn, William A.

“…Cells are capable of adapting to changes in their environment by synthesizing needed proteins and degrading superfluous ones. Pichia pastoris synthesizes…”
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Role of cAMP in the Regulation of Hepatocytic Autophagy by Holen, Ingunn, Gordon, Paul B., Strømhaug, Per E., Seglen, Per O.

“…To assess the role of cAMP in the regulation of autophagy, we examined the effects of cAMP analogues and cAMP‐elevating agents on freshly isolated rat…”
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Structural aspects of autophagy by Seglen, P O, Berg, T O, Blankson, H, Fengsrud, M, Holen, I, Strømhaug, P E

“…As a first step towards isolation of autophagic sequestering membranes (phagophores), we have purified autophagosomes from rat hepatocytes. Lysosomes were…”
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