Search Results - "Strøm Larsen, Bjarke"

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    Water-soluble chitosan eases development of mucoadhesive buccal films and wafers for children by Korelc, Karin, Larsen, Bjarke Strøm, Gašperlin, Mirjana, Tho, Ingunn

    Published in International journal of pharmaceutics (25-01-2023)
    “…[Display omitted] •Films and wafers from water-soluble chitosan were compared to conventional chitosan.•Different solvents and manufacturing techniques…”
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    Journal Article
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    A unifying approach to drug-in-polymer solubility prediction: Streamlining experimental workflow and analysis by Larsen, Bjarke Strøm, Meiland, Peter, Tzdaka, Eidan, Tho, Ingunn, Rades, Thomas

    “…[Display omitted] This method paper describes currently used experimental methods to predict the drug-in-polymer solubility of amorphous solid dispersions and…”
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    A new method to determine drug-polymer solubility through enthalpy of melting and mixing by Meiland, Peter, Larsen, Bjarke Strøm, Knopp, Matthias Manne, Tho, Ingunn, Rades, Thomas

    Published in International journal of pharmaceutics (15-12-2022)
    “…Through modelling the enthalpy of melting and mixing of a drug with a polymer, it is possible to determine the solubility of the drug in the polymeric matrix…”
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    Co-release of paclitaxel and encequidar from amorphous solid dispersions increase oral paclitaxel bioavailability in rats by Petersen, Emilie Fynbo, Larsen, Bjarke Strøm, Nielsen, Rasmus Blaaholm, Pijpers, Ils, Versweyveld, Dries, Holm, René, Tho, Ingunn, Snoeys, Jan, Nielsen, Carsten Uhd

    Published in International journal of pharmaceutics (10-04-2024)
    “…[Display omitted] •Paclitaxel dissolution rates: ASD in PVP-K30 > ASD in HPMC-5 > ASD in HPMC-4K.•Dissolution from amorphous solid dispersions of paclitaxel…”
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    Journal Article
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    Increased bioavailability of a P-gp substrate: Co-release of etoposide and zosuquidar from amorphous solid dispersions by Nielsen, Rasmus Blaaholm, Larsen, Bjarke Strøm, Holm, René, Pijpers, Ils, Snoeys, Jan, Nielsen, Ulla Gro, Tho, Ingunn, Nielsen, Carsten Uhd

    Published in International journal of pharmaceutics (25-07-2023)
    “…[Display omitted] •Release rates: pure drug ≈ ASD in PVP > ASD in HPMC5 > ASD in HPMC 4k.•Two compounds were co-administered as ASDs for coordinated…”
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    Journal Article
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    Impact of drug load and polymer molecular weight on the 3D microstructure of printed tablets by Larsen, Bjarke Strøm, Kissi, Eric, Nogueira, Liebert Parreiras, Genina, Natalja, Tho, Ingunn

    “…This study investigates the influence of drug load and polymer molecular weight on the structure of tablets three-dimensionally (3D) printed from the binary…”
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    Towards personalized drug delivery via semi-solid extrusion: Exploring poly(vinyl alcohol-co-vinyl acetate) copolymers for hydrochlorothiazide-loaded films by Korelc, Karin, Larsen, Bjarke Strøm, Heintze, Anna-Lena, Henrik-Klemens, Åke, Karlsson, Jakob, Larsson, Anette, Tho, Ingunn

    “…•Different PVA/PVAc copolymers were investigated for their properties.•Film preparation by semi-solid extrusion was suitable for all copolymers.•Properties of…”
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    Using dextran of different molecular weights to achieve faster freeze-drying and improved storage stability of lactate dehydrogenase by Larsen, Bjarke Strøm, Skytte, Jeppe, Svagan, Anna J., Meng-Lund, Helena, Grohganz, Holger, Löbmann, Korbinian

    Published in Pharmaceutical development and technology (16-03-2019)
    “…Freeze-drying of protein formulations is frequently used to maintain protein activity during storage. The freeze-drying process usually requires long primary…”
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    Using dextran of different molecular weights to achieve faster eeze-drying and improved storage stability of lactate dehydrogenase by Larsen, Bjarke Strom, Skytte, Jeppe, Svagan, Anna Justina, Meng-Lund, Helena, Grohganz, Holger, Löbmann, Korbinian

    “…Freeze-drying of protein formulations is frequently used to maintain otein activity during storage. The freeze-drying process usually quires long primary…”
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    Journal Article