Search Results - "Strøm Larsen, Bjarke"
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Co-administration of Intravenous Drugs: Rapidly Troubleshooting the Solid Form Composition of a Precipitate in a Multi-drug Mixture Using On-Site Raman Spectroscopy
Published in Molecular pharmaceutics (05-06-2023)“…Intravenous drugs are often co-administrated in the same intravenous catheter line due to which compatibility issues, such as complex precipitation processes…”
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Water-soluble chitosan eases development of mucoadhesive buccal films and wafers for children
Published in International journal of pharmaceutics (25-01-2023)“…[Display omitted] •Films and wafers from water-soluble chitosan were compared to conventional chitosan.•Different solvents and manufacturing techniques…”
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A unifying approach to drug-in-polymer solubility prediction: Streamlining experimental workflow and analysis
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2024)“…[Display omitted] This method paper describes currently used experimental methods to predict the drug-in-polymer solubility of amorphous solid dispersions and…”
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A new method to determine drug-polymer solubility through enthalpy of melting and mixing
Published in International journal of pharmaceutics (15-12-2022)“…Through modelling the enthalpy of melting and mixing of a drug with a polymer, it is possible to determine the solubility of the drug in the polymeric matrix…”
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Co-release of paclitaxel and encequidar from amorphous solid dispersions increase oral paclitaxel bioavailability in rats
Published in International journal of pharmaceutics (10-04-2024)“…[Display omitted] •Paclitaxel dissolution rates: ASD in PVP-K30 > ASD in HPMC-5 > ASD in HPMC-4K.•Dissolution from amorphous solid dispersions of paclitaxel…”
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Increased bioavailability of a P-gp substrate: Co-release of etoposide and zosuquidar from amorphous solid dispersions
Published in International journal of pharmaceutics (25-07-2023)“…[Display omitted] •Release rates: pure drug ≈ ASD in PVP > ASD in HPMC5 > ASD in HPMC 4k.•Two compounds were co-administered as ASDs for coordinated…”
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Impact of drug load and polymer molecular weight on the 3D microstructure of printed tablets
Published in European journal of pharmaceutical sciences (01-01-2024)“…This study investigates the influence of drug load and polymer molecular weight on the structure of tablets three-dimensionally (3D) printed from the binary…”
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Towards personalized drug delivery via semi-solid extrusion: Exploring poly(vinyl alcohol-co-vinyl acetate) copolymers for hydrochlorothiazide-loaded films
Published in European journal of pharmaceutical sciences (01-01-2024)“…•Different PVA/PVAc copolymers were investigated for their properties.•Film preparation by semi-solid extrusion was suitable for all copolymers.•Properties of…”
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Shifting the Focus from Dissolution to Permeation: Introducing the Meso-fluidic Chip for Permeability Assessment (MCPA)
Published in Journal of pharmaceutical sciences (01-05-2024)“…In response to the growing ethical and environmental concerns associated with animal testing, numerous in vitro tools of varying complexity and biorelevance…”
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Using dextran of different molecular weights to achieve faster freeze-drying and improved storage stability of lactate dehydrogenase
Published in Pharmaceutical development and technology (16-03-2019)“…Freeze-drying of protein formulations is frequently used to maintain protein activity during storage. The freeze-drying process usually requires long primary…”
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Using dextran of different molecular weights to achieve faster eeze-drying and improved storage stability of lactate dehydrogenase
Published in Pharmaceutical development and technology (2019)“…Freeze-drying of protein formulations is frequently used to maintain otein activity during storage. The freeze-drying process usually quires long primary…”
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