Search Results - "Stoycheva, Diana"
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Interleukin-7 Modulates Anti-Tumor CD8+ T Cell Responses via Its Action on Host Cells
Published in PloS one (22-07-2016)“…The adoptive transfer of antigen-specific CD8+ T cells is a promising approach for the treatment of chronic viral and malignant diseases. In order to improve…”
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2
Antagonism of interferon signaling by fibroblast growth factors promotes viral replication
Published in EMBO molecular medicine (07-09-2020)“…Fibroblast growth factors (FGFs) play key roles in the pathogenesis of different human diseases, but the cross‐talk between FGFs and other cytokines remains…”
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3
Interferon-γ Receptor Signaling in Dendritic Cells Restrains Spontaneous Proliferation of CD4 + T Cells in Chronic Lymphopenic Mice
Published in Frontiers in immunology (07-02-2019)“…In lymphopenic mice, T cells become activated and undergo lymphopenia-induced proliferation (LIP). However, not all T cells are equally sensitive to…”
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4
External cues to drive B cell function towards immunotherapy
Published in Acta biomaterialia (01-10-2021)“…Immunotherapy stands out as a powerful and promising therapeutic strategy in the treatment of cancer, infections, and autoimmune diseases. Adoptive immune…”
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5
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
Published in The EMBO journal (01-03-2021)“…Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infections. While the diagnostic value of anti‐N antibodies is clear, their role in…”
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6
Non‐neutralizing antibodies protect against chronic LCMV infection by promoting infection of inflammatory monocytes in mice
Published in European journal of immunology (01-06-2021)“…Antibodies play an important role in host defense against microorganisms. Besides direct microbicidal activities, antibodies can also provide indirect…”
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Two sequential layers of antibody‐mediated control of Legionella pneumophila infection
Published in European journal of immunology (01-09-2019)“…Protective immunity against intracellular pathogens, including bacteria, usually relies on cellular immunity. However, antibodies are also implicated in…”
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Nanoconfinement of microvilli alters gene expression and boosts T cell activation
Published in Proceedings of the National Academy of Sciences - PNAS (05-10-2021)“…T cells sense and respond to their local environment at the nanoscale by forming small actin-rich protrusions, called microvilli, which play critical roles in…”
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9
Interleukin-7 Modulates Anti-Tumor CD8.sup.+ T Cell Responses via Its Action on Host Cells
Published in PloS one (22-07-2016)“…The adoptive transfer of antigen-specific CD8.sup.+ T cells is a promising approach for the treatment of chronic viral and malignant diseases. In order to…”
Get full text
Journal Article -
10
IFN-γ regulates CD8+ memory T cell differentiation and survival in response to weak, but not strong, TCR signals
Published in The Journal of immunology (1950) (15-01-2015)“…In response to primary Ag contact, naive mouse CD8(+) T cells undergo clonal expansion and differentiate into effector T cells. After pathogen clearance, most…”
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Engineering T-cell activation for immunotherapy by mechanical forces
Published in Current opinion in biomedical engineering (01-06-2019)“…Adoptive immunotherapy relies on the isolation, modification, activation, and transfer of antigen-specific T-cells. With constant advances in bioengineering,…”
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12
IFN-gamma receptor signaling regulates memory CD8+ T cell differentiation
Published in The Journal of immunology (1950) (15-03-2010)“…IFN-gamma regulates multiple processes in the immune system. Although its antimicrobial effector functions are well described, less is known about the…”
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13
Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation
Published in The Journal of clinical investigation (01-06-2010)“…Identifying the antigens that have the potential to trigger endogenous antitumor responses in an individual cancer patient is likely to enhance the efficacy of…”
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14
IFN-{gamma} Receptor Signaling Regulates Memory CD8+ T Cell Differentiation
Published in The Journal of immunology (1950) (15-03-2010)Get full text
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