Search Results - "Stowers, S."

Advances in Extracellular Matrix-Mimetic Hydrogels to Guide Stem Cell Fate by Stowers, Ryan S

“…In the fields of regenerative medicine and tissue engineering, stem cells offer vast potential for treating or replacing diseased and damaged tissue. Much…”
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Dynamic phototuning of 3D hydrogel stiffness by Stowers, Ryan S., Allen, Shane C., Suggs, Laura J.

“…Significance Extracellular matrix (ECM) stiffness is an influential factor in many biological processes. Temporal changes in ECM stiffness are observed in…”
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Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility by Stowers, Ryan S., Shcherbina, Anna, Israeli, Johnny, Gruber, Joshua J., Chang, Julie, Nam, Sungmin, Rabiee, Atefeh, Teruel, Mary N., Snyder, Michael P., Kundaje, Anshul, Chaudhuri, Ovijit

“…In breast cancer, the increased stiffness of the extracellular matrix is a key driver of malignancy. Yet little is known about the epigenomic changes that…”
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Identification of cell context-dependent YAP-associated proteins reveals β1 and β4 integrin mediate YAP translocation independently of cell spreading by Lee, Joanna Y., Dominguez, Antonia A., Nam, Sungmin, Stowers, Ryan S., Qi, Lei. S, Chaudhuri, Ovijit

“…Yes-associated protein (YAP) is a transcriptional regulator and mechanotransducer, relaying extracellular matrix (ECM) stiffness into proliferative gene…”
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Engineering hydrogels for personalized disease modeling and regenerative medicine by Tayler, Ian M., Stowers, Ryan S.

“…Technological innovations and advances in scientific understanding have created an environment where data can be collected, analyzed, and interpreted at scale,…”
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Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling by Madl, Christopher M., LeSavage, Bauer L., Dewi, Ruby E., Dinh, Cong B., Stowers, Ryan S., Khariton, Margarita, Lampe, Kyle J., Nguyen, Duong, Chaudhuri, Ovijit, Enejder, Annika, Heilshorn, Sarah C.

“…Neural progenitor cell (NPC) culture within three-dimensional (3D) hydrogels is an attractive strategy for expanding a therapeutically relevant number of stem…”
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Clinical Value of Acute Rest Technetium-99m Tetrofosmin Tomographic Myocardial Perfusion Imaging in Patients With Acute Chest Pain and Nondiagnostic Electrocardiograms by Heller, Gary V, Stowers, Stephen A, Hendel, Robert C, Herman, Steven D, Daher, Edouard, Ahlberg, Alan W, Baron, Jack M, Mendes de Leon, Carlos F, Rizzo, John A, Wackers, Frans J.Th

“…Objectives. We sought to evaluate the clinical use and cost-analysis of acute rest technetium-99m (Tc-99m) tetrofosmin single-photon emission computed…”
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Limits of movement in the human knee. Effect of sectioning the posterior cruciate ligament and posterolateral structures by Grood, E S, Stowers, S F, Noyes, F R

“…We applied specific forces and moments to the knees of fifteen whole lower limbs of cadavera and measured, with a six degrees-of-freedom electrogoniometer, the…”
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Mitochondria are redistributed in Drosophila photoreceptors lacking Milton, a kinesin-associated protein by Górska-Andrzejak, J., Stowers, R.S., Borycz, J., Kostyleva, R., Schwarz, T.L., Meinertzhagen, I.A.

“…Photoreceptors are richly supplied with mitochondria, where they are required to meet the energetic demands, in the soma, of phototransduction and, in the…”
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Technetium-99m sestamibi myocardial perfusion imaging in the emergency room evaluation of chest pain by Hilton, Thomas C., Thompson, Randall C., Williams, Hugh J., Saylors, Robert, Fulmer, Holly, Stowers, Stephen A.

“…Objectives. The purpose of this investigation was to evaluate the practicality and short-term predictive value of acute myocardial perfusion imaging with…”
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Fibrin-based stem cell containing scaffold improves the dynamics of burn wound healing by Chung, Eunna, Rybalko, Viktoriya Y., Hsieh, Pei-Ling, Leal, Shannah L., Samano, Melissa A., Willauer, Alexandra N., Stowers, Ryan S., Natesan, Shanmugasundaram, Zamora, David O., Christy, Robert J., Suggs, Laura J.

“…ABSTRACT For severe burn injuries, successful medical intervention is accomplished by rapidly and safely providing physical barriers that can cover damaged…”
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Extracellular Matrix Stiffening Induces a Malignant Phenotypic Transition in Breast Epithelial Cells by Stowers, Ryan S., Allen, Shane C., Sanchez, Karla, Davis, Courtney L., Ebelt, Nancy D., Van Den Berg, Carla, Suggs, Laura J.

“…Tumors are much stiffer than healthy tissue, and progressively stiffen as the cancer develops. Tumor stiffening is largely the result of extracellular matrix…”
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Potential cost effectiveness of initial myocardial perfusion imaging for assessment of emergency department patients with chest pain by Radensky, Paul W., Hilton, Thomas C., Fulmer, Holly, McLaughlin, Beth A., Stowers, Stephen A.

“…Previous investigations have confirmed the diagnostic and predictive usefulness of initial single-photon emission computed tomography (SPECT) myocardial…”
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A PEGylated fibrin-based wound dressing with antimicrobial and angiogenic activity by Seetharaman, Shanmuganathan, Natesan, Shanmugasundaram, Stowers, Ryan S., Mullens, Conor, Baer, David G., Suggs, Laura J., Christy, Robert J.

“…Wounds sustained under battlefield conditions are considered to be contaminated and their initial treatment should focus on decreasing this contamination and…”
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An economic analysis of an aggressive diagnostic strategy with single photon emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department patients who present with chest pain but nondiagnostic electrocardiograms: Results from a randomized trial by Stowers, Stephen A., Eisenstein, Eric L., Wackers, Frans J.Th, Berman, Daniel S., Blackshear, Joseph L., Jones, Arthur D., Szymanski, Theodore J., Lam, Lai Choi, Simons, Tracey A., Natale, Donna, Paige, Kevin A., Wagner, Galen S.

“…Study Objective: Conventional emergency department testing strategies for patients with chest pain often do not provide unequivocal diagnosis of acute coronary…”
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Activating Mutations of the c-Ha-ras Protooncogene in Chemically Induced Hepatomas of the Male B6C3 F1 Mouse by Wiseman, Roger W., Stowers, Shari J., Miller, Elizabeth C., Anderson, Marshall W., Miller, James A.

“…Activated c-Ha-ras protooncogenes have recently been identified in the DNA of some spontaneous hepatic tumors found in 2-year-old B6C3 F1 mice. Activation of…”
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Multifunctional nanoscale strategies for enhancing and monitoring blood vessel regeneration by Chung, Eunna, Ricles, Laura M., Stowers, Ryan S., Nam, Seung Yun, Emelianov, Stanislav Y., Suggs, Laura J.

“… [Display omitted] ► ECM-mimicking nanoscale scaffolds can enhance vascular cell activities. ► Biomedical imaging with nanocontrast agents allows for…”
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Axonal Transport of Mitochondria to Synapses Depends on Milton, a Novel Drosophila Protein by Stowers, R.Steven, Megeath, Laura J., Górska-Andrzejak, Jolanta, Meinertzhagen, Ian A., Schwarz, Thomas L.

“…A protein required to localize mitochondria to Drosophila nerve terminals has been identified genetically. Photoreceptors mutant for milton show aberrant…”
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Activated Oncogenes in B6C3F1 Mouse Liver Tumors: Implications for Risk Assessment by Reynolds, Steven H., Stowers, Shari J., Patterson, Rachel M., Maronpot, Robert R., Aaronson, Stuart A., Anderson, Marshall W.

“…The validity of mouse liver tumor end points in assessing the potential hazards of chemical exposure to humans is a controversial but important issue, since…”
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Detection and Identification of Activated Oncogenes in Spontaneously Occurring Benign and Malignant Hepatocellular Tumors of the B6C3F1 Mouse by Reynolds, Steven H., Stowers, Shari J., Maronpot, Robert R., Anderson, Marshall W., Aaronson, Stuart A.

“…Species- and strain-specific spontaneously occurring tumors have been observed in rodents maintained under normal laboratory conditions. Elucidation of the…”
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