Search Results - "Stower, Michael J."

Prospective identification of tumorigenic prostate cancer stem cells by COLLINS, Anne T, BERRY, Paul A, HYDE, Catherine, STOWER, Michael J, MAITLAND, Norman J

“…Existing therapies for prostate cancer eradicates the bulk of cells within a tumor. However, most patients go on to develop androgen-independent disease that…”
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JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells by KROON, Paula, BERRY, Paul A, MAITLAND, Norman J, COLLINS, Anne T, STOWER, Michael J, RODRIGUES, Greta, MANN, Vincent M, SIMMS, Matthew, BHASIN, Deepak, CHETTIAR, Somsundaram, CHENGLONG LI, LI, Pui-Kai

“…Interleukin (IL)-6 overexpression and constitutive STAT3 activation occur in many cancers, including prostate cancer. However, their contribution to prostate…”
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Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells by Ulukaya, Engin, Frame, Fiona M, Cevatemre, Buse, Pellacani, Davide, Walker, Hannah, Mann, Vincent M, Simms, Matthew S, Stower, Michael J, Yilmaz, Veysel T, Maitland, Norman J

“…The outcome for patients with advanced metastatic and recurrent prostate cancer is still poor. Therefore, new chemotherapeutics are required, especially for…”
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Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer by Pellacani, Davide, Packer, Richard J, Frame, Fiona M, Oldridge, Emma E, Berry, Paul A, Labarthe, Marie-Christine, Stower, Michael J, Simms, Matthew S, Collins, Anne T, Maitland, Norman J

“…Epigenetic control is essential for maintenance of tissue hierarchy and correct differentiation. In cancer, this hierarchical structure is altered and…”
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Enhanced expression of vimentin in motile prostate cell lines and in poorly differentiated and metastatic prostate carcinoma by Lang, Shona H., Hyde, Catherine, Reid, Ian N., Hitchcock, Ian S., Hart, Claire A., Gordon Bryden, A. A., Villette, Jean-Marie, Stower, Michael J., Maitland, Norman J.

“…BACKGROUND The metastatic potential of a series of prostate cell lines was analysed by measuring motility and invasiveness, and further correlated to the…”
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Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions by Birnie, Richard, Bryce, Steven D, Roome, Claire, Dussupt, Vincent, Droop, Alastair, Lang, Shona H, Berry, Paul A, Hyde, Catherine F, Lewis, John L, Stower, Michael J, Maitland, Norman J, Collins, Anne T

“…The tumor-initiating capacity of many cancers is considered to reside in a small subpopulation of cells (cancer stem cells). We have previously shown that rare…”
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Monoallelic expression of TMPRSS2/ERG in prostate cancer stem cells by Polson, Euan S., Lewis, John L., Celik, Hamza, Mann, Vincent M., Stower, Michael J., Simms, Matthew S., Rodrigues, Greta, Collins, Anne T., Maitland, Norman J.

“…While chromosomal translocations have a fundamental role in the development of several human leukaemias, their role in solid tumour development has been…”
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Re: A pilot study of the tolerability of two BCG maintenance regimens in the treatment of high risk superficial bladder cancer by Taylor, Joby, Stower, Michael J

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The prevalence of chronic kidney disease requiring nephrological referral in patients with non-visible haematuria by Taylor, Joby, Wilson, J. Russell, Chan, Koon H, Urwin, Graeme H, Stower, Michael J

“…Abstract Objective To quantify the proportion of patients attending for urological investigation of non-visible haematuria who meet criteria for referral to…”
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Three-year outcomes of a visible haematuria clinic—No initial role for urine cytology? by Munro, Nicholas. P, Stower, Michael J, Urwin, Graeme H, Chan, Koon. H, Wilson, J. Russell

“…Summary Objective To review patients presenting in a specialist macroscopic (visible) haematuria clinic during 2005, incorporating 3 years of follow-up, and to…”
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Abstract B25: DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation by Pellacani, Davide, Kestoras, Dimitra, Droop, Alastair P., Frame, Fiona M., Berry, Paul A., Lawrence, Mitchell G., Stower, Michael J., Simms, Matthew S., Mann, Vincent M., Collins, Anne T., Risbridger, Gail P., Maitland, Norman J.

“…Prostate cancer (CaP) is mostly composed of differentiated luminal cells, but contains a small subpopulation of undifferentiated basal cells (including…”
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Abstract 5198: Elucidation of dynamic prostate epithelial hierarchy: Insights into transcriptional and epigenetic regulatory mechanisms by Rane, Jayant K., Pellacani, Davide, Droop, Alastair P., Ylipää, Antti, Stower, Michael J., Simms, Matthew S., Mann, Vincet M., Visakorpi, Tapio, Collins, Anne T., Maitland, Norman J.

“…The aim of present investigation is to elucidate the complex stem cell dynamics within prostate cancer, which can be utilized to design novel diagnostic and…”
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Abstract 5209: Prostate cancer progenitor cells have distinct DNA methylation profile which changes upon differentiation by Pellacani, Davide, Kestoras, Dimitra, Droop, Alastair P., Wilson, Katherine M., Polson, Euan S., Hager, Stefanie, Frame, Fiona M., Berry, Paul A., Stower, Michael J., Simms, Matthew S., Mann, Vincent M., Collins, Anne T., Maitland, Norman J.

“…Prostate cancer is phenotypically, genetically and epigenetically heterogeneous. In the present study we have dissected the epigenetic heterogeneity of…”
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Experimental prostate epithelial morphogenesis in response to stroma and three-dimensional matrigel culture by LANG, Shona H, STARK, Meg, COLLINS, Anne, PAUL, Alan B, STOWER, Michael J, MAITLAND, Norman J

“…To reproduce the structural and functional differentiation of human prostatic acini in vivo, prostatic epithelial and stromal cells derived from human primary…”
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Differential Cytotoxic Activity of a Novel Palladium-Based Compound on Prostate Cell Lines, Primary Prostate Epithelial Cells and Prostate Stem Cells. e64278 by Ulukaya, Engin, Frame, Fiona M, Cevatemre, Buse, Pellacani, Davide, Walker, Hannah, Mann, Vincent M, Simms, Matthew S, Stower, Michael J, Yilmaz, Veysel T, Maitland, Norman J

“…The outcome for patients with advanced metastatic and recurrent prostate cancer is still poor. Therefore, new chemotherapeutics are required, especially for…”
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Letter to the Editor by Taylor, Joby, Stower, Michael J.

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