Search Results - "Stow, J. L."

Recycling endosome-dependent and -independent mechanisms for IL-10 secretion in LPS-activated macrophages by Stanley, A. C., Lieu, Z. Z., Wall, A. A., Venturato, J., Khromykh, T., Hamilton, N. A., Gleeson, P. A., Stow, J. L.

“…Two post‐Golgi pathways where IL‐10 is trafficked, ensures its secretion from activated macrophages under different physiological conditions. IL‐10 is a key…”
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Protein trafficking and polarity in kidney epithelium: from cell biology to physiology by Brown, D, Stow, J L

“…The transepithelial movement of fluids, electrolytes, and larger molecules is achieved by the activity of a host of specialized transporting proteins,…”
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Actin filaments regulate epithelial Na+ channel activity by Cantiello, H F, Stow, J L, Prat, A G, Ausiello, D A

“…The functional role of the cytoskeleton in the control of ion channel activity is unknown. In the present study, immunocolocalization of Na+ channels with…”
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Identification of human intestinal trefoil factor. Goblet cell-specific expression of a peptide targeted for apical secretion by Podolsky, D.K, Lynch-Devaney, K, Stow, J.L, Oates, P, Murgue, B, DeBeaumont, M, Sands, B.E, Mahida, Y.R

“…Trefoil peptides are a recently recognized group of small peptides abundantly produced at mucosal surfaces that offer the opportunity to define mechanisms of…”
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A Heterotrimeric G Protein, Gα i-3, on Golgi Membranes Regulates the Secretion of a Heparan Sulfate Proteoglycan in LLC-PK1 Epithelial Cells by Stow, Jennifer L., de Almeida, J. Bruno, Narula, Navneet, Holtzman, Eliezer J., Ercolani, Louis, Ausiello, Dennis A.

“…A heterotrimeric Gαi subunit, α i-3, is localized on Golgi membranes in LLC-PK1 and NRK epithelial cells where it colocalizes with mannosidase II by…”
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Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles by Beaumont, Kimberley A., Shekar, Sri L., Newton, Richard A., James, Michael R., Stow, Jennifer L., Duffy, David L., Sturm, Richard A.

“…The human melanocortin-1 receptor (MC1R) is a G-protein coupled receptor involved in the regulation of pigmentation. Several MC1R variant alleles are…”
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Acute epithelial injury in the rat small intestine in vivo is associated with expanded expression of transforming growth factor alpha and beta by Dignass, A U, Stow, J L, Babyatsky, M W

“…BACKGROUND--Previous studies have shown the importance of transforming growth factors alpha and beta (TGF alpha and TGF beta) in modulating epithelial cell…”
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Entry of cholera toxin into polarized human intestinal epithelial cells : identification of an early brefeldin A sensitive event required for A1-peptide generation by LENCER, W. I, DE ALMEIDA, J. B, MOE, S, STOW, J. L, AUSIELLO, D. A, MADARA, J. L

“…The effect of brefeldin-A (BFA), a reversible inhibitor of vesicular transport, on cholera toxin (CT)-induced Cl- secretion (Isc) was examined in the polarized…”
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Heterologous expression of delta F508 CFTR results in decreased sialylation of membrane glycoconjugates by Dosanjh, A, Lencer, W, Brown, D, Ausiello, D A, Stow, J L

“…The cystic fibrosis transmembrane conductance regulator (CFTR) is commonly mutated in cystic fibrosis to the delta F508 CFTR. CFTR has been shown to function…”
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Recycling of E-Cadherin: A Potential Mechanism for Regulating Cadherin Dynamics by Le, Tam Luan, Yap, Alpha S., Stow, Jennifer L.

“…E-Cadherin plays critical roles in many aspects of cell adhesion, epithelial development, and the establishment and maintenance of epithelial polarity. The…”
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Distinct Coated Vesicles Labeled for p200 Bud from Trans-Golgi Network Membranes by Narula, Navneet, Stow, Jennifer L.

“…Golgi-associated cytoplasmic proteins, such as the coatomer protein complex, are required for vesicle budding and trafficking. We have previously described a…”
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Basement Membrane Heparan Sulfate Proteoglycans are Concentrated in the Laminae Rarae and in Podocytes of the Rat Renal Glomerulus by Stow, Jennifer L., Sawada, Hajime, Farquhar, Marilyn Gist

“…A polyclonal antibody was raised against a proteoglycan fraction purified from extracts of isolated rat renal glomeruli. The antibody was characterized by…”
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Identification of a 200-kD, Brefeldin-Sensitive Protein on Golgi Membranes by Narula, Navneet, McMorrow, Isabel, Plopper, George, Doherty, Joanne, Matlin, Karl S., Burke, Brian, Stow, Jennifer L.

“…A mAb AD7, raised against canine liver Golgi membranes, recognizes a novel, 200-kD protein (p200) which is found in a wide variety of cultured cell lines…”
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Binding of the cytosolic p200 protein to Golgi membranes is regulated by heterotrimeric G proteins by DE ALMEIDA, J. B, DOHERTY, J, AUSIELLO, D. A, STOW, J. L

“…The formation of vesicles for protein trafficking requires the dynamic binding of cytosolic coat proteins onto Golgi membranes and this binding is regulated by…”
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Hyaluronate is a component of crescents in rat autoimmune glomerulonephritis by Nishikawa, K, Andres, G, Bhan, A K, McCluskey, R T, Collins, A B, Stow, J L, Stamenkovic, I

“…Crescent formation is a major feature of rapidly progressive glomerulonephritis and is generally associated with a poor prognosis. Crescents are formed by…”
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Distinctive Populations of Basement Membrane and Cell Membrane Heparan Sulfate Proteoglycans Are Produced by Cultured Cell Lines by Stow, Jennifer L., Farquhar, Marilyn Gist

“…We have investigated the nature and distribution of different populations of heparan sulfate proteoglycans (HSPGs) in several cell lines in culture. Clone 9…”
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Purified epithelial Na+ channel complex contains the pertussis toxin-sensitive G alpha i-3 protein by Ausiello, D A, Stow, J L, Cantiello, H F, de Almeida, J B, Benos, D J

“…We have recently demonstrated that the amiloride-sensitive Na+ channel in the apical membrane of the renal epithelial cell line, A6, is modulated by the alpha…”
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Dependence on pH of polarized sorting of secreted proteins by CAPLAN, M. J, STOW, J. L, NEWMAN, A. P, MADRI, J, ANDERSON, H. C, FARQUHAR, M. G, PALADE, G. E, JAMIESON, J. D

“…The plasma membranes of epithelial cells are divided into apical and basolateral domains. These two surfaces are characterized by markedly different protein…”
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A Dileucine Motif Targets E-cadherin to the Basolateral Cell Surface in Madin-Darby Canine Kidney and LLC-PK1 Epithelial Cells by Miranda, Kevin C., Khromykh, Tatiana, Christy, Perpetina, Le, Tam Luan, Gottardi, Cara J., Yap, Alpha S., Stow, Jennifer L., Teasdale, Rohan D.

“…E-cadherin is a major adherens junction protein of epithelial cells, with a central role in cell-cell adhesion and cell polarity. Newly synthesized E-cadherin…”
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Role of myristoylation in membrane attachment and function of G alpha i-3 on Golgi membranes by Brand, S H, Holtzman, E J, Scher, D A, Ausiello, D A, Stow, J L

“…Heterotrimeric G protein alpha-subunits localized on the cytoplasmic face of Golgi membranes are involved in regulating vesicle trafficking and protein…”
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