Search Results - "Stovicek, Olivia"

Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets by Dugan, Haley L., Stamper, Christopher T., Li, Lei, Changrob, Siriruk, Asby, Nicholas W., Halfmann, Peter J., Zheng, Nai-Ying, Huang, Min, Shaw, Dustin G., Cobb, Mari S., Erickson, Steven A., Guthmiller, Jenna J., Stovicek, Olivia, Wang, Jiaolong, Winkler, Emma S., Madariaga, Maria Lucia, Shanmugarajah, Kumaran, Jansen, Maud O., Amanat, Fatima, Stewart, Isabelle, Utset, Henry A., Huang, Jun, Nelson, Christopher A., Dai, Ya-Nan, Hall, Paige D., Jedrzejczak, Robert P., Joachimiak, Andrzej, Krammer, Florian, Diamond, Michael S., Fremont, Daved H., Kawaoka, Yoshihiro, Wilson, Patrick C.

“…Dissecting the evolution of memory B cells (MBCs) against SARS-CoV-2 is critical for understanding antibody recall upon secondary exposure. Here, we used…”
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Broadly neutralizing antibodies target a haemagglutinin anchor epitope by Guthmiller, Jenna J., Han, Julianna, Utset, Henry A., Li, Lei, Lan, Linda Yu-Ling, Henry, Carole, Stamper, Christopher T., McMahon, Meagan, O’Dell, George, Fernández-Quintero, Monica L., Freyn, Alec W., Amanat, Fatima, Stovicek, Olivia, Gentles, Lauren, Richey, Sara T., de la Peña, Alba Torrents, Rosado, Victoria, Dugan, Haley L., Zheng, Nai-Ying, Tepora, Micah E., Bitar, Dalia J., Changrob, Siriruk, Strohmeier, Shirin, Huang, Min, García-Sastre, Adolfo, Liedl, Klaus R., Bloom, Jesse D., Nachbagauer, Raffael, Palese, Peter, Krammer, Florian, Coughlan, Lynda, Ward, Andrew B., Wilson, Patrick C.

“…Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential to provide near universal protection against…”
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Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses by Guthmiller, Jenna J., Lan, Linda Yu-Ling, Fernández-Quintero, Monica L., Han, Julianna, Utset, Henry A., Bitar, Dalia J., Hamel, Natalie J., Stovicek, Olivia, Li, Lei, Tepora, Micah, Henry, Carole, Neu, Karlynn E., Dugan, Haley L., Borowska, Marta T., Chen, Yao-Qing, Liu, Sean T.H., Stamper, Christopher T., Zheng, Nai-Ying, Huang, Min, Palm, Anna-Karin E., García-Sastre, Adolfo, Nachbagauer, Raffael, Palese, Peter, Coughlan, Lynda, Krammer, Florian, Ward, Andrew B., Liedl, Klaus R., Wilson, Patrick C.

“…Polyreactivity is the ability of a single antibody to bind to multiple molecularly distinct antigens and is a common feature of antibodies induced upon…”
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SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike by Guthmiller, Jenna J, Stovicek, Olivia, Wang, Jiaolong, Changrob, Siriruk, Li, Lei, Halfmann, Peter, Zheng, Nai-Ying, Utset, Henry, Stamper, Christopher T, Dugan, Haley L, Miller, William D, Huang, Min, Dai, Ya-Nan, Nelson, Christopher A, Hall, Paige D, Jansen, Maud, Shanmugarajah, Kumaran, Donington, Jessica S, Krammer, Florian, Fremont, Daved H, Joachimiak, Andrzej, Kawaoka, Yoshihiro, Tesic, Vera, Madariaga, Maria Lucia, Wilson, Patrick C

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently causing a global pandemic. The antigen specificity of the antibody response mounted…”
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Improved integration of single-cell transcriptome and surface protein expression by LinQ-View by Li, Lei, Dugan, Haley L., Stamper, Christopher T., Lan, Linda Yu-Ling, Asby, Nicholas W., Knight, Matthew, Stovicek, Olivia, Zheng, Nai-Ying, Madariaga, Maria Lucia, Shanmugarajah, Kumaran, Jansen, Maud O., Changrob, Siriruk, Utset, Henry A., Henry, Carole, Nelson, Christopher, Jedrzejczak, Robert P., Fremont, Daved H., Joachimiak, Andrzej, Krammer, Florian, Huang, Jun, Khan, Aly A., Wilson, Patrick C.

“…Multimodal advances in single-cell sequencing have enabled the simultaneous quantification of cell surface protein expression alongside unbiased…”
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Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair by Zhu, Chenxu, Lu, Lining, Zhang, Jun, Yue, Zongwei, Song, Jinghui, Zong, Shuai, Liu, Menghao, Stovicek, Olivia, Gao, Yi Qin, Yi, Chengqi

“…NEIL1 (Nei-like 1) is a DNA repair glycosylase guarding the mammalian genome against oxidized DNA bases. As the first enzymes in the base-excision repair…”
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Stability of nitroxide biradical TOTAPOL in biological samples by McCoy, Kelsey M., Rogawski, Rivkah, Stovicek, Olivia, McDermott, Ann E.

“…[Display omitted] •TOTAPOL is quickly reduced in E. coli cell pellets, suspensions, and lysates.•4 mM and 8 mM N-ethylmaleimide treatment of cells prevents…”
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Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans by Dugan, Haley L, Guthmiller, Jenna J, Arevalo, Philip, Huang, Min, Chen, Yao-Qing, Neu, Karlynn E, Henry, Carole, Zheng, Nai-Ying, Lan, Linda Yu-Ling, Tepora, Micah E, Stovicek, Olivia, Bitar, Dalia, Palm, Anna-Karin E, Stamper, Christopher T, Changrob, Siriruk, Utset, Henry A, Coughlan, Lynda, Krammer, Florian, Cobey, Sarah, Wilson, Patrick C

“…Humans are repeatedly exposed to variants of influenza virus throughout their lifetime. As a result, preexisting influenza-specific memory B cells can dominate…”
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First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes by Guthmiller, Jenna J, Han, Julianna, Li, Lei, Freyn, Alec W, Liu, Sean T H, Stovicek, Olivia, Stamper, Christopher T, Dugan, Haley L, Tepora, Micah E, Utset, Henry A, Bitar, Dalia J, Hamel, Natalie J, Changrob, Siriruk, Zheng, Nai-Ying, Huang, Min, Krammer, Florian, Nachbagauer, Raffael, Palese, Peter, Ward, Andrew B, Wilson, Patrick C

“…Broadly neutralizing antibodies are critical for protection against both drifted and shifted influenza viruses. Here, we reveal that first exposure to the 2009…”
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Librator: a platform for the optimized analysis, design, and expression of mutable influenza viral antigens by Li, Lei, Changrob, Siriruk, Fu, Yanbin, Stovicek, Olivia, Guthmiller, Jenna J, McGrath, Joshua J C, Dugan, Haley L, Stamper, Christopher T, Zheng, Nai-Ying, Huang, Min, Wilson, Patrick C

“…Abstract Artificial mutagenesis and protein engineering have laid the foundation for antigenic characterization and universal vaccine design for influenza…”
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