Search Results - "Stover, D. G."

Homologous recombination deficiency and host anti-tumor immunity in triple-negative breast cancer by Telli, M. L., Stover, D. G., Loi, S., Aparicio, S., Carey, L. A., Domchek, S. M., Newman, L., Sledge, G. W., Winer, E. P.

“…Purpose Triple-negative breast cancer (TNBC) is associated with worse outcomes relative to other breast cancer subtypes. Chemotherapy remains the…”
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Prognostic value of plasma circulating tumor DNA fraction across four common cancer types: a real-world outcomes study by Reichert, Z.R., Morgan, T.M., Li, G., Castellanos, E., Snow, T., Dall’Olio, F.G., Madison, R.W., Fine, A.D., Oxnard, G.R., Graf, R.P., Stover, D.G.

“…Genomic analysis of circulating tumor DNA (ctDNA) is increasingly incorporated into the clinical management of patients with advanced cancer. Beyond tumor…”
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Long-term impact of prior rituximab therapy and early lymphocyte recovery on auto-SCT outcome for diffuse large B-cell lymphoma by Stover, D G, Reddy, V K, Shyr, Y, Savani, B N, Reddy, N

“…Early lymphocyte recovery following auto-SCT for non-Hodgkin's lymphoma (NHL) has been reported to be associated with improved outcome. The significance of…”
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Chemotherapy-induced gut microbiome disruption, inflammation, and cognitive decline in female patients with breast cancer by Otto-Dobos, L.D., Grant, C.V., Lahoud, A.A., Wilcox, O.R., Strehle, L.D., Loman, B.R., Adarkwah Yiadom, S., Seng, M.M., Halloy, N.R., Russart, K.L.G., Carpenter, K.M., Dawson, E., Sardesai, S.D., Williams, N.O., Gatti-Mays, M.E., Stover, D.G., Sudheendra, P.K., Wesolowski, R., Kiecolt-Glaser, J.K., Bailey, M.T., Andridge, R.R., Pyter, L.M.

“…•Chemotherapy induces microbiome disruption, inflammation, and cognitive decline.•The resulting microbiome disruption relates to cognitive decline and…”
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Clinical outcomes of early-stage triple-negative breast cancer after neoadjuvant chemotherapy according to HER2-low status by Raghavendra, A.S., Zakon, D.B., Jin, Q., Strahan, A., Grimm, M., Hughes, M.E., Cherian, M., Vincuilla, J., Parker, T., Tarantino, P., Mittendorf, E.A., King, T.A., Valero, V., Tripathy, D., Tolaney, S.M., Tayob, N., Lin, N.U., Stover, D.G., Barcenas, C.H., Garrido-Castro, A.C.

“…The impact of human epidermal growth factor receptor 2 (HER2) expression determined by immunohistochemistry (IHC) on outcomes in early-stage triple-negative…”
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Mutational status of overexpressed p16 in head and neck cancer: evidence for germline mutation of p16/p14ARF by Lang, J C, Borchers, J, Danahey, D, Smith, S, Stover, D G, Agrawal, A, Malone, J P, Schuller, D E, Weghorst, C M, Holinga, A J, Lingam, K, Patel, C R, Esham, B

“…Inactivation of the p16 tumor suppressor gene is a common phenomenon in squamous cell carcinoma of the head and neck (SCCHN). Less commonly described is the…”
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Simultaneous metastasis of melanoma and lung adenocarcinoma to hilar lymph nodes and pleural effusion after renal transplantation by Tse, J. Y., Stover, D. G., Chebib, I.

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The community and preclinical education: the mock epidemic by Walker, R B, Savory, L, Stover, G D

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Analysis of BRAF and KRAS mutations in colorectal cancer and rectal carcinogenesis via fluorescent allele-specific PCR by Stover, D. G., Cushman-Vokoun, A. M., Vnencak-Jones, C. L., Berlin, J.

“…Abstract only 436 Background: Molecular analysis has become increasingly relevant in the evaluation of colorectal carcinomas. Mutations in Ras-MAPK pathway…”
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Abstract P1-09-06: Gene-set enrichment analysis (GSEA) of breast tissue from healthy women with less than six months history of breastfeeding shows enrichment in Hedgehog signaling, notch signaling and luminal progenitor gene signatures by Basree, MM, Shinde, N, Palettas, M, Weng, D, Stover, DG, Sizemore, GM, Shields, P, Majumder, S, Ramaswamy, B

“…Abstract Introduction: Multiple epidemiological studies have shown that prolonged breastfeeding is associated with a reduced risk of developing triple…”
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Abstract P3-07-07: Withdrawn by Jiang, Y-Z, Ma, D, Suo, C, Shi, J, Xue, M, Stover, DG, Verschraegen, C, Kaklamani, V, Wang, P, Shi, L, Huang, W, Shao, Z-M

“…Abstract This abstract was withdrawn by the authors. Citation Format: Jiang Y-Z, Ma D, Suo C, Shi J, Xue M, Stover DG, Verschraegen C, Kaklamani V, Wang P, Shi…”
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Abstract P1-07-05: Integrated transcriptional analysis of the triple negative 'proliferation paradox': High proliferation, chemosensitivity, and poor prognosis by Stover, DG, Selfors, LM, Winer, EP, Partridge, AH, Barry, WT

“…Abstract Background: In triple-negative breast cancers (TNBC), high proliferation is associated with greater chemosensitivity but, paradoxically, also…”
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Abstract P4-01-17: Aggressive subgroups of metastatic triple-negative breast cancer: Inflammatory breast cancer and young patients in the Dana-Farber cell-free DNA cohort by Singh, J, Asad, S, Nock, W, Zhang, Y, Adams, E, Damicis, A, Parsons, HA, Adalsteinsson, VA, Winer, EP, Lin, NU, Partridge, AH, Overmoyer, B, Stover, DG

“…Abstract Background: Relative to other metastatic breast cancer subtypes, metastatic triple-negative breast cancer (mTNBC) has a shorter duration of response…”
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Abstract P3-07-08: Multi-omic predictor of rapid and late relapse in primary triple negative breast cancer by Zhang, Y, Nock, W, Asad, S, Adams, E, Singh, J, Damicis, A, Lustberg, MB, Noonan, A, Reinbolt, R, Sardesai, S, VanDeusen, J, Wesolowski, R, Williams, N, Ramaswamy, B, Stover, DG

“…Abstract Background: Triple-negative breast cancer (TNBC) is a heterogeneous disease. Clinically, we observe three distinct TNBC outcomes: 1) rapid relapse…”
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Abstract PD6-09: The immune microenvironment in hormone receptor-positive breast cancer patients and relationship to treatment outcome following preoperative chemotherapy plus bevacizumab by Waks, AG, Stover, DG, Barry, W, Dillon, D, Gjini, E, Rodig, SJ, Brock, J, Baltay, M, Savoie, J, Winer, EP, Krop, I, Tolaney, SM

“…Abstract Background: Hormone receptor-positive (HR+) tumors have fewer tumor-infiltrating lymphocytes (TILs) and lower response rates to immune checkpoint…”
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Abstract P1-09-01: CD8+ T-cell gene expression and signatures in breast cancer and adjacent normal breast tissue: Association with body mass index, alcohol intake, and age at diagnosis by Damicis, A, Heng, YJ, Kensler, K, Asad, S, Adams, E, Singh, J, Zhang, Y, Nock, W, Wesolowski, R, Williams, N, Reinbolt, R, Sardesai, S, VanDeusen, J, Noonan, A, Lustberg, MB, Ramaswamy, B, Eliassen, AH, Hankinson, SE, Tamimi, R, Stover, DG

“…Abstract Background: Our understanding of mediators of immune infiltration in breast cancer and normal breast tissue remains limited. We hypothesize that…”
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Abstract P3-07-31: Immune activation signatures identify a subset of ER+ breast cancers with increased pathologic complete response to neoadjuvant chemotherapy by Stover, DG, Waks, AG, Erica, ML, Brugge, JS, Winer, EP, Selfors, LM

“…Abstract Background: Proliferation is the strongest predictor of response to neoadjuvant chemotherapy in estrogen receptor-positive (ER+) breast cancer…”
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Abstract PD5-02: Not presented by Guerrero-Zotano, AL, Stricker, TP, Hutchinson, KE, Stover, DG, Formisano, L, Lee, K-M, Schwarz, LJ, Giltnane, JM, Jansen, VM, Gavila, J, Perez-Fidalgo, A, Lluch, A, Llombart, A, Bayar, MA, Michiels, S, André, F, Arnedos, M, Ruiz, A, Arteaga, CL

“…Abstract This abstract was not presented at the symposium…”
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Abstract P5-21-10: Phase 2 study and correlative analyses of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic, triple-negative breast cancer by Stover, DG, Gil Del Alcazar, CR, Tolaney, SM, Bardia, A, Guo, H, Balko, JM, Overmoyer, BA, Gelman, RS, Lloyd, M, Wang, V, Brock, JE, Winer, EP, Polyak, K, Lin, NU

“…Abstract Background: Preclinical data supports a role for the IL-6/JAK2/STAT3 signaling pathway in breast cancer (BC). Ruxolitinib is an orally bioavailable…”
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Abstract GS3-07: Genome-wide copy number analysis of chemotherapy-resistant metastatic triple-negative breast cancer from cell-free DNA by Stover, DG, Parsons, HA, Ha, G, Freeman, S, Barry, B, Guo, H, Choudhury, A, Gydush, G, Reed, S, Rhoades, J, Rotem, D, Hughes, ME, Dillon, DA, Partridge, AH, Wagle, N, Krop, IE, Getz, G, Golub, TA, Love, JC, Winer, EP, Tolaney, SM, Lin, NU, Adalsteinsson, VA

“…Abstract Introduction: Triple-negative breast cancer (TNBC) is a poor prognosis breast cancer subset characterized by relatively few mutations but extensive…”
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