Search Results - "Stout, Julie C."
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Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data
Published in Lancet neurology (01-07-2013)“…Summary Background TRACK-HD is a multinational prospective observational study of Huntington's disease (HD) that examines clinical and biological findings of…”
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Intensity Matters: High-intensity Interval Exercise Enhances Motor Cortex Plasticity More Than Moderate Exercise
Published in Cerebral cortex (New York, N.Y. 1991) (10-01-2020)“…Abstract A single bout of cardiovascular exercise can enhance plasticity in human cortex; however, the intensity required for optimal enhancement is debated…”
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Huntington disease: natural history, biomarkers and prospects for therapeutics
Published in Nature reviews. Neurology (01-04-2014)“…Key Points No disease-modifying treatments are currently available for Huntington disease (HD), but clinical trials of potential compounds are imminent;…”
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Oxytocin Attenuates Amygdala Reactivity to Fear in Generalized Social Anxiety Disorder
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2010)“…Patients with generalized social anxiety disorder (GSAD) exhibit heightened activation of the amygdala in response to social cues conveying threat (eg,…”
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Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
Published in Lancet neurology (2011)“…Summary Background TRACK-HD is a prospective observational study of Huntington's disease (HD) that examines disease progression in premanifest individuals…”
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Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data
Published in Lancet neurology (2012)“…Summary Background TRACK-HD is a prospective observational biomarker study in premanifest and early Huntington's disease (HD). In this report we define a…”
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Psychiatric Symptoms in Huntington’s Disease before Diagnosis: The Predict-HD Study
Published in Biological psychiatry (1969) (15-12-2007)“…Background Psychiatric disturbances are relatively common in manifest Huntington’s disease (HD), but less is known about these symptoms in the earliest phase…”
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Gut dysbiosis in Huntington’s disease: associations among gut microbiota, cognitive performance and clinical outcomes
Published in Brain communications (01-01-2020)“…Abstract Huntington’s disease is characterized by a triad of motor, cognitive and psychiatric impairments, as well as unintended weight loss. Although much of…”
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Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data
Published in Lancet neurology (01-09-2009)“…Summary Background Huntington's disease (HD) is an autosomal dominant, fully penetrant, neurodegenerative disease that most commonly affects adults in…”
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Motor cortex plasticity response to acute cardiorespiratory exercise and intermittent theta-burst stimulation is attenuated in premanifest and early Huntington’s disease
Published in Scientific reports (20-01-2022)“…Huntington’s disease (HD) mouse models suggest that cardiovascular exercise may enhance neuroplasticity and delay disease signs, however, the effects of…”
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Iron accumulation in the basal ganglia in Huntington's disease: cross-sectional data from the IMAGE-HD study
Published in Journal of neurology, neurosurgery and psychiatry (01-05-2016)“…ObjectivesTo measure iron accumulation in the basal ganglia in Huntington's disease (HD) using quantitative susceptibility mapping (QSM), and to ascertain its…”
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Longitudinal change in white matter microstructure in Huntington's disease: The IMAGE-HD study
Published in Neurobiology of disease (01-02-2015)“…Abstract Objective To quantify 18-month changes in white matter microstructure in premanifest (pre-HD) and symptomatic Huntington's disease (symp-HD). To…”
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Optokinetic nystagmus reflects perceptual directions in the onset binocular rivalry in Parkinson's disease
Published in PloS one (13-03-2017)“…Optokinetic nystagmus (OKN), the reflexive eye movements evoked by a moving field, has recently gained interest among researchers as a useful tool to assess…”
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Hippocampal 5-HT1A Receptor and Spatial Learning and Memory
Published in Frontiers in pharmacology (10-12-2015)“…Spatial cognition is fundamental for survival in the topographically complex environments inhabited by humans and other animals. The hippocampus, which has a…”
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Operationalizing compensation over time in neurodegenerative disease
Published in Brain (London, England : 1878) (01-04-2017)“…In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensation. Gregory, Long et al …”
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White matter connectivity reflects clinical and cognitive status in Huntington's disease
Published in Neurobiology of disease (01-05-2014)“…Abstract Objective To investigate structural connectivity and the relationship between axonal microstructure and clinical, cognitive, and motor functions in…”
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Strategic and non-strategic problem gamblers differ on decision-making under risk and ambiguity
Published in Addiction (Abingdon, England) (01-07-2014)“…Aims To analyse problem gamblers' decision‐making under conditions of risk and ambiguity, investigate underlying psychological factors associated with their…”
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Using Cognitive Models to Map Relations between Neuropsychological Disorders and Human Decision-Making Deficits
Published in Psychological science (01-12-2005)“…Findings from a complex decision-making task (the Iowa gambling task) show that individuals with neuropsychological disorders are characterized by…”
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A Contribution of Cognitive Decision Models to Clinical Assessment: Decomposing Performance on the Bechara Gambling Task
Published in Psychological assessment (01-09-2002)“…The Bechara simulated gambling task is a popular method of examining decision-making deficits exhibited by people with brain damage, psychopathology,…”
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Multi-modal neuroimaging in premanifest and early Huntington's disease: 18 month longitudinal data from the IMAGE-HD study
Published in PloS one (16-09-2013)“…IMAGE-HD is an Australian based multi-modal longitudinal magnetic resonance imaging (MRI) study in premanifest and early symptomatic Huntington's disease…”
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