Search Results - "Stottmann, R.W."

The Impact of CRISPR/Cas9-Based Genomic Engineering on Biomedical Research and Medicine by Go, D E, Stottmann, R W

“…There has been prolonged and significant interest in manipulating the genome for a wide range of applications in biomedical research and medicine. An existing…”
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Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain by Stottmann, R.W., Tran, P.V., Turbe-Doan, A., Beier, D.R.

“…Organizing centers in the developing brain provide an assortment of instructive patterning cues, including Sonic hedgehog ( Shh). Here we characterize the…”
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A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse by Stottmann, R W, Donlin, M, Hafner, A, Bernard, A, Sinclair, D A, Beier, D R

“…Human cortical malformations, including lissencephaly, polymicrogyria and other diseases of neurodevelopment, have been associated with mutations in…”
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Identification of a Van der Woude syndrome mutation in the cleft palate 1 mutant mouse by Stottmann, R.W., Bjork, B.C., Doyle, J.B., Beier, D.R.

“…Mutations in Interferon Regulatory Factor 6 (IRF6) have been identified in two human allelic syndromes with cleft lip and/or palate: Van der Woude (VWS) and…”
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