Search Results - "Stott, David J"

High-Sensitivity Cardiac Troponin Concentration and Risk of First-Ever Cardiovascular Outcomes in 154,052 Participants by Willeit, Peter, Welsh, Paul, Evans, Jonathan D.W., Tschiderer, Lena, Boachie, Charles, Jukema, J. Wouter, Ford, Ian, Trompet, Stella, Stott, David J., Kearney, Patricia M., Mooijaart, Simon P., Kiechl, Stefan, Di Angelantonio, Emanuele, Sattar, Naveed

“…High-sensitivity assays can quantify cardiac troponins I and T (hs-cTnI, hs-cTnT) in individuals with no clinically manifest myocardial injury. The goal of…”
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Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age by Deelen, Joris, Beekman, Marian, Uh, Hae-Won, Broer, Linda, Ayers, Kristin L, Tan, Qihua, Kamatani, Yoichiro, Bennet, Anna M, Tamm, Riin, Trompet, Stella, Guðbjartsson, Daníel F, Flachsbart, Friederike, Rose, Giuseppina, Viktorin, Alexander, Fischer, Krista, Nygaard, Marianne, Cordell, Heather J, Crocco, Paolina, van den Akker, Erik B, Böhringer, Stefan, Helmer, Quinta, Nelson, Christopher P, Saunders, Gary I, Alver, Maris, Andersen-Ranberg, Karen, Breen, Marie E, van der Breggen, Ruud, Caliebe, Amke, Capri, Miriam, Cevenini, Elisa, Collerton, Joanna C, Dato, Serena, Davies, Karen, Ford, Ian, Gampe, Jutta, Garagnani, Paolo, de Geus, Eco J C, Harrow, Jennifer, van Heemst, Diana, Heijmans, Bastiaan T, Heinsen, Femke-Anouska, Hottenga, Jouke-Jan, Hofman, Albert, Jeune, Bernard, Jonsson, Palmi V, Lathrop, Mark, Lechner, Doris, Martin-Ruiz, Carmen, Mcnerlan, Susan E, Mihailov, Evelin, Montesanto, Alberto, Mooijaart, Simon P, Murphy, Anne, Nohr, Ellen A, Paternoster, Lavinia, Postmus, Iris, Rivadeneira, Fernando, Ross, Owen A, Salvioli, Stefano, Sattar, Naveed, Schreiber, Stefan, Stefánsson, Hreinn, Stott, David J, Tiemeier, Henning, Uitterlinden, André G, Westendorp, Rudi G J, Willemsen, Gonneke, Samani, Nilesh J, Galan, Pilar, Sørensen, Thorkild I A, Boomsma, Dorret I, Jukema, J Wouter, Rea, Irene Maeve, Passarino, Giuseppe, de Craen, Anton J M, Christensen, Kaare, Nebel, Almut, Stefánsson, Kári, Metspalu, Andres, Magnusson, Patrik, Blanché, Hélène, Christiansen, Lene, Kirkwood, Thomas B L, van Duijn, Cornelia M, Franceschi, Claudio, Houwing-Duistermaat, Jeanine J, Slagboom, P Eline

“…The genetic contribution to the variation in human lifespan is ∼ 25%. Despite the large number of identified disease-susceptibility loci, it is not known which…”
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Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis by Chaker, Layal, Baumgartner, Christine, den Elzen, Wendy P. J, Ikram, M. Arfan, Blum, Manuel R, Collet, Tinh-Hai, Bakker, Stephan J. L, Dehghan, Abbas, Drechsler, Christiane, Luben, Robert N, Hofman, Albert, Portegies, Marileen L. P, Medici, Marco, Iervasi, Giorgio, Stott, David J, Ford, Ian, Bremner, Alexandra, Wanner, Christoph, Ferrucci, Luigi, Newman, Anne B, Dullaart, Robin P, Sgarbi, José A, Ceresini, Graziano, Maciel, Rui M. B, Westendorp, Rudi G, Jukema, J. Wouter, Imaizumi, Misa, Franklyn, Jayne A, Bauer, Douglas C, Walsh, John P, Razvi, Salman, Khaw, Kay-Tee, Cappola, Anne R, Völzke, Henry, Franco, Oscar H, Gussekloo, Jacobijn, Rodondi, Nicolas, Peeters, Robin P

“…Objective: The objective was to determine the risk of stroke associated with subclinical hypothyroidism. Data Sources and Study Selection: Published…”
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Outcomes, experiences and palliative care in major stroke: a multicentre, mixed-method, longitudinal study by Kendall, Marilyn, MA PhD, Boyd, Kirsty, PhD, Murray, Scott A., MD, Cowey, Eileen, MN PhD, Mead, Gillian, MD, Barber, Mark, MD, McAlpine, Christine, MBChB, Stott, David J., MD

“…ABSTRACT BACKGROUND Case fatality after total anterior circulation stroke is high. Our objective was to describe the experiences and needs of patients and…”
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Elevated troponin after stroke: a systematic review by Kerr, Gillian, Ray, Gautamananda, Wu, Olivia, Stott, David J, Langhorne, Peter

“…Troponin levels are elevated in some acute stroke patients, but the clinical significance of this is unclear. We conducted a systematic review of studies…”
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Genetic Risk Prediction of Atrial Fibrillation by Lubitz, Steven A, Yin, Xiaoyan, Lin, Henry J, Kolek, Matthew, Smith, J Gustav, Trompet, Stella, Rienstra, Michiel, Rost, Natalia S, Teixeira, Pedro L, Almgren, Peter, Anderson, Christopher D, Chen, Lin Y, Engström, Gunnar, Ford, Ian, Furie, Karen L, Guo, Xiuqing, Larson, Martin G, Lunetta, Kathryn L, Macfarlane, Peter W, Psaty, Bruce M, Soliman, Elsayed Z, Sotoodehnia, Nona, Stott, David J, Taylor, Kent D, Weng, Lu-Chen, Yao, Jie, Geelhoed, Bastiaan, Verweij, Niek, Siland, Joylene E, Kathiresan, Sekar, Roselli, Carolina, Roden, Dan, van der Harst, Pim, Darbar, Dawood, Jukema, J Wouter, Melander, Olle, Rosand, Jonathan, Rotter, Jerome I, Heckbert, Susan R, Ellinor, Patrick T, Alonso, Alvaro, Benjamin, Emelia J

“…BACKGROUND—Atrial fibrillation (AF) has a substantial genetic basis. Identification of individuals at greatest AF risk could minimize the incidence of…”
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Comparative validity of informant tools for assessing pre‐stroke cognitive impairment by Taylor‐Rowan, Martin, McGuire, Lucy, Hafdi, Melanie, Evans, Jonathan, Stott, David J., Wetherall, Kirsty, Elliott, Emma, Drozdowska, Bogna, Quinn, Terence J.

“…Objectives Various informant‐based questionnaires are used in clinical practice to screen for pre‐stroke cognitive problems. However, there is no guidance on…”
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Subclinical Thyroid Dysfunction and the Risk of Heart Failure in Older Persons at High Cardiovascular Risk by Nanchen, David, Gussekloo, Jacobijn, Westendorp, Rudi G. J, Stott, David J, Jukema, J. Wouter, Trompet, Stella, Ford, Ian, Welsh, Paul, Sattar, Naveed, Macfarlane, Peter W, Mooijaart, Simon P, Rodondi, Nicolas, de Craen, Anton J. M, on behalf of the PROSPER Group

“…Context: Subclinical thyroid dysfunction is common in older people. However, its clinical importance is uncertain. Objective: Our objective was to determine…”
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Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis by Chaker, Layal, Baumgartner, Christine, den Elzen, Wendy P. J, Collet, Tinh-Hai, Ikram, M. Arfan, Blum, Manuel R, Dehghan, Abbas, Drechsler, Christiane, Luben, Robert N, Portegies, Marileen L. P, Iervasi, Giorgio, Medici, Marco, Stott, David J, Dullaart, Robin P, Ford, Ian, Bremner, Alexandra, Newman, Anne B, Wanner, Christoph, Sgarbi, José A, Dörr, Marcus, Longstreth, W. T, Psaty, Bruce M, Ferrucci, Luigi, Maciel, Rui M. B, Westendorp, Rudi G, Jukema, J. Wouter, Ceresini, Graziano, Imaizumi, Misa, Hofman, Albert, Bakker, Stephan J. L, Franklyn, Jayne A, Khaw, Kay-Tee, Bauer, Douglas C, Walsh, John P, Razvi, Salman, Gussekloo, Jacobijn, Völzke, Henry, Franco, Oscar H, Cappola, Anne R, Rodondi, Nicolas, Peeters, Robin P, for the Thyroid Studies Collaboration

“…Context: The currently applied reference ranges for thyroid function are under debate. Despite evidence that thyroid function within the reference range is…”
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Resting heart rate, heart rate variability and functional decline in old age by Ogliari, Giulia, Mahinrad, Simin, Stott, David J, Jukema, J Wouter, Mooijaart, Simon P, Macfarlane, Peter W, Clark, Elaine N, Kearney, Patricia M, Westendorp, Rudi G J, de Craen, Anton J M, Sabayan, Behnam

“…Heart rate and heart rate variability, markers of cardiac autonomic function, have been linked with cardiovascular disease. We investigated whether heart rate…”
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Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium by Dehghan, Abbas, Bis, Joshua C, White, Charles C, Smith, Albert Vernon, Morrison, Alanna C, Cupples, L Adrienne, Trompet, Stella, Chasman, Daniel I, Lumley, Thomas, Völker, Uwe, Buckley, Brendan M, Ding, Jingzhong, Jensen, Majken K, Folsom, Aaron R, Kritchevsky, Stephen B, Girman, Cynthia J, Ford, Ian, Dörr, Marcus, Salomaa, Veikko, Uitterlinden, André G, Eiriksdottir, Gudny, Vasan, Ramachandran S, Franceschini, Nora, Carty, Cara L, Virtamo, Jarmo, Demissie, Serkalem, Amouyel, Philippe, Arveiler, Dominique, Heckbert, Susan R, Ferrières, Jean, Ducimetière, Pierre, Smith, Nicholas L, Wang, Ying A, Siscovick, David S, Rice, Kenneth M, Wiklund, Per-Gunnar, Taylor, Kent D, Evans, Alun, Kee, Frank, Rotter, Jerome I, Karvanen, Juha, Kuulasmaa, Kari, Heiss, Gerardo, Kraft, Peter, Launer, Lenore J, Hofman, Albert, Markus, Marcello R P, Rose, Lynda M, Silander, Kaisa, Wagner, Peter, Benjamin, Emelia J, Lohman, Kurt, Stott, David J, Rivadeneira, Fernando, Harris, Tamara B, Levy, Daniel, Liu, Yongmei, Rimm, Eric B, Jukema, J Wouter, Völzke, Henry, Ridker, Paul M, Blankenberg, Stefan, Franco, Oscar H, Gudnason, Vilmundur, Psaty, Bruce M, Boerwinkle, Eric, O'Donnell, Christopher J

“…Data are limited on genome-wide association studies (GWAS) for incident coronary heart disease (CHD). Moreover, it is not known whether genetic variants…”
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Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies by Sattar, Naveed, Prof, McConnachie, Alex, PhD, Shaper, A Gerald, Prof, Blauw, Gerard J, MD, Buckley, Brendan M, Prof, de Craen, Anton J, PhD, Ford, Ian, Prof, Forouhi, Nita G, FFPH, Freeman, Dilys J, PhD, Jukema, J Wouter, Prof, Lennon, Lucy, MSc, Macfarlane, Peter W, Prof, Murphy, Michael B, Prof, Packard, Chris J, Prof, Stott, David J, Prof, Westendorp, Rudi G, Prof, Whincup, Peter H, Prof, Shepherd, James, Prof, Wannamethee, S Goya, PhD

“…Summary Background Clinical use of criteria for metabolic syndrome to simultaneously predict risk of cardiovascular disease and diabetes remains uncertain. We…”
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Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a general practice (primary care) setting by Harrison, Jennifer K, Fearon, Patricia, Noel-Storr, Anna H, McShane, Rupert, Stott, David J, Quinn, Terry J

“…The IQCODE (Informant Questionnaire for Cognitive Decline in the Elderly) is a commonly used questionnaire based tool that uses collateral information to…”
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Pravastatin and cognitive function in the elderly. Results of the PROSPER study by Trompet, Stella, van Vliet, Peter, de Craen, Anton J. M., Jolles, Jelle, Buckley, Brendan M., Murphy, Michael B., Ford, Ian, Macfarlane, Peter W., Sattar, Naveed, Packard, Chris J., Stott, David J., Shepherd, Jim, Bollen, Eduard L. E. M., Blauw, Gerard J., Jukema, J. Wouter, Westendorp, Rudi G. J.

“…Observational studies have given conflicting results about the effect of statins in preventing dementia and cognitive decline. Moreover, observational studies…”
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Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume by Vojinovic, Dina, Adams, Hieab H., Jian, Xueqiu, Yang, Qiong, Smith, Albert Vernon, Bis, Joshua C., Teumer, Alexander, Scholz, Markus, Armstrong, Nicola J., Hofer, Edith, Saba, Yasaman, Luciano, Michelle, Bernard, Manon, Trompet, Stella, Yang, Jingyun, Gillespie, Nathan A., van der Lee, Sven J., Neumann, Alexander, Ahmad, Shahzad, Andreassen, Ole A., Ames, David, Amin, Najaf, Arfanakis, Konstantinos, Bastin, Mark E., Becker, Diane M., Beiser, Alexa S., Beyer, Frauke, Brodaty, Henry, Bryan, R. Nick, Bülow, Robin, Dale, Anders M., De Jager, Philip L., Deary, Ian J., DeCarli, Charles, Fleischman, Debra A., Gottesman, Rebecca F., van der Grond, Jeroen, Gudnason, Vilmundur, Harris, Tamara B., Homuth, Georg, Knopman, David S., Kwok, John B., Lewis, Cora E., Li, Shuo, Loeffler, Markus, Lopez, Oscar L., Maillard, Pauline, El Marroun, Hanan, Mather, Karen A., Mosley, Thomas H., Muetzel, Ryan L., Nauck, Matthias, Nyquist, Paul A., Panizzon, Matthew S., Pausova, Zdenka, Psaty, Bruce M., Rice, Ken, Rotter, Jerome I., Royle, Natalie, Satizabal, Claudia L., Schmidt, Reinhold, Schofield, Peter R., Schreiner, Pamela J., Sidney, Stephen, Stott, David J., Thalamuthu, Anbupalam, Uitterlinden, Andre G., Valdés Hernández, Maria C., Vernooij, Meike W., Wen, Wei, White, Tonya, Witte, A. Veronica, Wittfeld, Katharina, Wright, Margaret J., Yanek, Lisa R., Tiemeier, Henning, Kremen, William S., Bennett, David A., Jukema, J. Wouter, Paus, Tomas, Wardlaw, Joanna M., Schmidt, Helena, Sachdev, Perminder S., Villringer, Arno, Grabe, Hans Jörgen, Longstreth, W T, van Duijn, Cornelia M., Launer, Lenore J., Seshadri, Sudha, Ikram, M Arfan, Fornage, Myriam

“…The volume of the lateral ventricles (LV) increases with age and their abnormal enlargement is a key feature of several neurological and psychiatric diseases…”
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Impaired Endogenous Thrombolysis in Acute Coronary Syndrome Patients Predicts Cardiovascular Death and Nonfatal Myocardial Infarction by Saraf, Smriti, MB BS, MPhil, Christopoulos, Christos, LRCP&SI, MB, BCh, BAO, Salha, Imen Ben, MB BS, Stott, David J., DPhil, MSc, Gorog, Diana A., MD, PhD

“…Objectives Our objective was to assess endogenous thrombolytic activity in acute coronary syndrome (ACS) patients and relate this to their likelihood of future…”
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Do vascular risk factors explain the association between socioeconomic status and stroke incidence: a meta-analysis by Kerr, Gillian D, Slavin, Helen, Clark, Donna, Coupar, Fiona, Langhorne, Peter, Stott, David J

“…Reduced socioeconomic status (SES) is associated with an increased risk of stroke, although the mechanism is not clear. It may be that those with lower SES…”
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A smartphone-based test for the assessment of attention deficits in delirium: A case-control diagnostic test accuracy study in older hospitalised patients by Tieges, Zoë, Stott, David J, Shaw, Robert, Tang, Elaine, Rutter, Lisa-Marie, Nouzova, Eva, Duncan, Nikki, Clarke, Caoimhe, Weir, Christopher J, Assi, Valentina, Ensor, Hannah, Barnett, Jennifer H, Evans, Jonathan, Green, Samantha, Hendry, Kirsty, Thomson, Meigan, McKeever, Jenny, Middleton, Duncan G, Parks, Stuart, Walsh, Tim, Weir, Alexander J, Wilson, Elizabeth, Quasim, Tara, MacLullich, Alasdair M J

“…Delirium is a common and serious acute neuropsychiatric syndrome which is often missed in routine clinical care. Inattention is the core cognitive feature…”
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Cerebral Microbleeds Are Predictive of Mortality in the Elderly by ALTMANN-SCHNEIDER, Irmhild, TROMPET, Stella, DE CRAEN, Anton J. M, VAN ES, Adriaan C. G. M, WOUTER JUKEMA, J, STOTT, David J, SATTAR, Naveed, WESTENDORP, Rudi G. J, VAN BUCHEM, Mark A, VAN DER GROND, Jeroen

“…To investigate the prognostic value of cerebral microbleeds (CMB) regarding overall, cardiovascular-related, and stroke-related mortality and to investigate…”
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The association of kidney function and cognitive decline in older patients at risk of cardiovascular disease: a longitudinal data analysis by Zijlstra, Laurien E, Trompet, Stella, Mooijaart, Simon P, van Buren, Marjolijn, Sattar, Naveed, Stott, David J, Jukema, J Wouter

“…Chronic kidney disease (CKD) has been identified as a significant direct marker for cognitive decline, but controversy exists regarding the magnitude of the…”
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