Search Results - "Stothers, L."

MyD88-dependent signaling drives toll-like receptor-induced trained immunity in macrophages by Owen, Allison M, Luan, Liming, Burelbach, Katherine R, McBride, Margaret A, Stothers, Cody L, Boykin, Olivia A, Sivanesam, Kalkena, Schaedel, Jessica F, Patil, Tazeen K, Wang, Jingbin, Hernandez, Antonio, Patil, Naeem K, Sherwood, Edward R, Bohannon, Julia K

“…Immunocompromised populations are highly vulnerable to developing life-threatening infections. Strategies to protect patients with weak immune responses are…”
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The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma by McBride, Margaret A, Owen, Allison M, Stothers, Cody L, Hernandez, Antonio, Luan, Liming, Burelbach, Katherine R, Patil, Tazeen K, Bohannon, Julia K, Sherwood, Edward R, Patil, Naeem K

“…Critically ill, severely injured and high-risk surgical patients are vulnerable to secondary infections during hospitalization and after hospital discharge…”
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Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection by Hernandez, Antonio, Patil, Naeem K., Stothers, Cody L., Luan, Liming, McBride, Margaret A., Owen, Allison M., Burelbach, Katherine R., Williams, David L., Sherwood, Edward R., Bohannon, Julia K.

“…[Display omitted] Infectious diseases remain a threat to critically ill patients, particularly with the rise of antibiotic-resistant bacteria. Septic shock…”
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unique covalent bond in basement membrane is a primordial innovation for tissue evolution by Fidler, Aaron L., Vanacore, Roberto M., Chetyrkin, Sergei V., Pedchenko, Vadim K., Bhave, Gautam, Yin, Viravuth P., Stothers, Cody L., Rose, Kristie Lindsey, McDonald, W. Hayes, Clark, Travis A., Borz, Dorin-Bogdan, Steele, Robert E., Ivy, Michael T., Aspirnauts, The, Hudson, Julie K., Hudson, Billy G.

“…Basement membrane, a specialized ECM that underlies polarized epithelium of eumetazoans, provides signaling cues that regulate cell behavior and function in…”
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Cranberry juice for the prevention of pediatric urinary tract infection: a randomized controlled trial by Afshar, K, Stothers, L, Scott, H, MacNeily, A E

“…Proanthocyanidins found in cranberry have been reported to have in vitro and in vivo antibacterial activity. We determined the effectiveness of cranberry juice…”
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Traumatic spinal cord injury in Uganda: a prevention strategy and mechanism to improve home care by Stothers, L, Macnab, A J, Mukisa, R, Mutabazi, S, Bajunirwe, F

“…In low- and middle-income countries (LMICs), the burden of traumatic spinal cord injury (TSCI) is largely unknown. The estimated incidence of TSCI in LMICs is…”
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The burden of bladder outlet obstruction in men in rural Uganda by Stothers, L, Mutabazi, S, Mukisa, R, Macnab, A J

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An integrative review of standardized clinical evaluation tool utilization in anticholinergic drug trials for neurogenic lower urinary tract dysfunction by Stothers, L, Tsang, B, Nigro, M, Lazare, D, Macnab, A

“…Study design: To review prospective and randomized trials studying anticholinergic therapy for neurogenic bladder in SCI to identify whether trials included…”
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Hypoxia-inducible factor-1α regulation of myeloid cells by Stothers, C. L., Luan, L., Fensterheim, B. A., Bohannon, J. K.

“…Hematopoietic myeloblasts give rise to macrophages, dendritic cells, and neutrophils. Circulating myeloid cells detect invading microbes using pattern…”
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A systematic review and comparison of questionnaires in the management of spinal cord injury, multiple sclerosis and the neurogenic bladder by Tsang, B., Stothers, L., Macnab, A., Lazare, D., Nigro, M.

“…Aims Validated questionnaires are increasingly the preferred method used to obtain historical information. Specialized questionnaires exist validated for…”
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Loss of Sirtuin 1 (SIRT1) potentiates endothelial dysfunction via impaired glycolysis during infectious challenge by Stark, Ryan J., Koch, Stephen R., Stothers, Cody L., Pourquoi, Allison, Lamb, Celia K., Miller, Michael R., Choi, Hyehun

“…Dear editor Sepsis is an exaggerated host response to infection that despite advances in early recognition and intervention, remains a common cause of…”
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Community-based provision of direct-acting antiviral therapy for hepatitis C: study protocol and challenges of a randomized controlled trial by Wade, A J, Doyle, J S, Gane, E, Stedman, C, Draper, B, Iser, D, Roberts, S K, Kemp, W, Petrie, D, Scott, N, Higgs, P, Agius, P A, Roney, J, Stothers, L, Thompson, A J, Hellard, M E

“…To achieve the World Health Organization hepatitis C virus (HCV) elimination targets, it is essential to increase access to treatment. Direct-acting antiviral…”
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Mid-YouTube Slings: A Systematic Appraisal pf Social Media on Information Quality, Surgical Content and Bias about Mid-urethral Slings by Larouche, M, Stothers, L, Geoffrion, R, Lazare, D, Clancy, A, Koenig, N, Cundiff, G.W

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Tolerability of solifenacin and oxybutynin immediate release in older (>65 years) and younger ( 65 years) patients with overactive bladder: sub-analysis from a Canadian, randomized, double-blind study by Herschorn, S., Pommerville, P., Stothers, L., Egerdie, B., Gajewski, J., Carlson, K., Radomski, S., Drutz, H., Schulz, J., Barkin, J., Hirshberg, E., Corcos, J.

“…Abstract Objective: Overactive bladder (OAB) is a common condition whose prevalence increases with age. Antimuscarinic agents are the pharmacologic treatment…”
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β-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages by Stothers, Cody L, Burelbach, Katherine R, Owen, Allison M, Patil, Naeem K, McBride, Margaret A, Bohannon, Julia K, Luan, Liming, Hernandez, Antonio, Patil, Tazeen K, Williams, David L, Sherwood, Edward R

“…Bacterial infections are a common and deadly threat to vulnerable patients. Alternative strategies to fight infection are needed. β-Glucan, an immunomodulator…”
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Innate Immune Memory and the Host Response to Infection by Sherwood, Edward R, Burelbach, Katherine R, McBride, Margaret A, Stothers, Cody L, Owen, Allison M, Hernandez, Antonio, Patil, Naeem K, Williams, David L, Bohannon, Julia K

“…Unlike the adaptive immune system, the innate immune system has classically been characterized as being devoid of memory functions. However, recent research…”
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MP-10.20: Receiver operator curves describing near infrared spectroscopy (NIRS) changes during pressure flow studies in men with obstruction by McNab, A, Stothers, L

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The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism by Fensterheim, Benjamin A, Young, Jamey D, Luan, Liming, Kleinbard, Ruby R, Stothers, Cody L, Patil, Naeem K, McAtee-Pereira, Allison G, Guo, Yin, Trenary, Irina, Hernandez, Antonio, Fults, Jessica B, Williams, David L, Sherwood, Edward R, Bohannon, Julia K

“…Monophosphoryl lipid A (MPLA) is a clinically used TLR4 agonist that has been found to drive nonspecific resistance to infection for up to 2 wk. However, the…”
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Bacteria- and fungus-derived PAMPs induce innate immune memory via similar functional, metabolic, and transcriptional adaptations by McBride, Margaret A, Stothers, Cody L, Fensterheim, Benjamin A, Caja, Katherine R, Owen, Allison M, Hernandez, Antonio, Bohannon, Julia K, Patil, Naeem K, Ali, Sabah, Dalal, Sujata, Rahim, Mohsin, Trenary, Irina A, Young, Jamey D, Williams, David L, Sherwood, Edward R

“…Exposure to pathogen-associated molecular patterns (PAMPs) induces an augmented, broad-spectrum antimicrobial response to subsequent infection, a phenomenon…”
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Immunoresponsive Gene 1 Facilitates TLR4-agonist-Induced Augmentation of Innate Antimicrobial Immunity by McBride, Margaret A, Caja, Katherine R, Patil, Tazeen K, Owen, Allison M, Luan, Liming, Bohannon, Julia K, Hernandez, Antonio, Stothers, Cody L, Trenary, Irina A, Rahim, Mohsin, Young, Jamey D, Calcutt, M Wade, Stephens, Victoria R, Davis, Xenia, Oliver, Mary A, Hao, Dan, Si, Clara, McRae, Malik, Nguyen, Kenny K, Davis, Nicholas S, Wang, Jingbin, Patil, Naeem K, Sherwood, Edward R

“…Treatment with the toll-like receptor (TLR) 4 agonist monophosphoryl lipid A (MPLA) conditions innate immunocytes to respond robustly to subsequent infection,…”
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