Search Results - "Storts, Douglas R"
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Massively parallel sequencing of short tandem repeats—Population data and mixture analysis results for the PowerSeq™ system
Published in Forensic science international : genetics (01-09-2016)“…Highlights • Sequencing of STRs reveals substantial variation in addition to length variation. • Sequence variation of 17 STRs was assessed for three globally…”
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Match criteria for human cell line authentication: Where do we draw the line?
Published in International journal of cancer (01-06-2013)“…Continuous human cell lines have been used extensively as models for biomedical research. In working with these cell lines, researchers are often unaware of…”
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Improved Detection of Microsatellite Instability in Early Colorectal Lesions
Published in PloS one (07-08-2015)“…Microsatellite instability (MSI) occurs in over 90% of Lynch syndrome cancers and is considered a hallmark of the disease. MSI is an early event in colon tumor…”
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Developmental validation of the PowerPlex® Y23 System: A single multiplex Y-STR analysis system for casework and database samples
Published in Forensic science international : genetics (01-02-2013)“…Abstract The PowerPlex® Y23 System combines the seventeen Y-STR loci in current commercially available Y-STR kits (DYS19, DYS385a/b, DYS389I/II, DYS390,…”
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Developmental validation of the PowerPlex® Fusion System for analysis of casework and reference samples: A 24-locus multiplex for new database standards
Published in Forensic science international : genetics (01-09-2014)“…Abstract The original CODIS database based on 13 core STR loci has been overwhelmingly successful for matching suspects with evidence. Yet there remain…”
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Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues
Published in In vitro cellular & developmental biology. Animal (01-10-2010)“…Cell misidentification and cross-contamination have plagued biomedical research for as long as cells have been employed as research tools. Examples of…”
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Developmental validation of the PowerPlex® 16 HS System: An improved 16-locus fluorescent STR multiplex
Published in Forensic science international : genetics (01-07-2010)“…Abstract STR multiplexes remain the cornerstone of genotyping forensic samples. The PowerPlex® 16 HS System contains the core CODIS loci: D3S1358, D5S818,…”
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Developmental validation of a real-time PCR assay for the simultaneous quantification of total human and male DNA
Published in Forensic science international : genetics (01-12-2008)“…Abstract Multiplex human short tandem repeat analysis demands reliable DNA quantification to consistently produce interpretable genotypes. The Plexor® HY…”
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An evaluation of the PowerSeq™ Auto System: A multiplex short tandem repeat marker kit compatible with massively parallel sequencing
Published in Forensic science international : genetics (01-11-2015)“…Highlights • PowerSeq Auto System and MiSeq can generate concordant result with CE-based methods. • Single source full profiles could be obtained using as…”
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A Highly Sensitive Pan-Cancer Test for Microsatellite Instability
Published in The Journal of molecular diagnostics : JMD (01-11-2023)“…Microsatellite instability (MSI) is an evolving biomarker for cancer detection and treatment. MSI was first used to identify patients with Lynch syndrome, a…”
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Alternative Probe-Based Detection Systems in Quantitative PCR
Published in The Journal of molecular diagnostics : JMD (01-11-2014)“…This commentary highlights the article by Murray et al that describes novel probe systems for real-time PCR that provide improvements relative to dual-labeled…”
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High sensitivity multiplex short tandem repeat loci analyses with massively parallel sequencing
Published in Forensic science international : genetics (01-05-2015)“…Highlights • Multiplex STR typing of 17 STRs and the Amelogenin locus is feasible by MPS. • Sensitivity of detection is comparable with that of CE-based…”
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Human DNA quantification and sample quality assessment: Developmental validation of the PowerQuant® system
Published in Forensic science international : genetics (01-07-2016)“…Highlights • The PowerQuant® System was developed to quantify human DNA and assess sample quality. • A developmental validation following SWGDAM guidelines was…”
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Cell Lines as Biological Models: Practical Steps for More Reliable Research
Published in Chemical research in toxicology (16-09-2019)“…Research in toxicology relies on in vitro models such as cell lines. These living models are prone to change and may be described in publications with…”
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Developmental validation of the PowerPlex® Fusion 6C System
Published in Forensic science international : genetics (01-03-2016)“…Highlights • The PowerPlex® Fusion 6C System is a new 6-dye, 27-locus, STR multiplex. • A multisite study following SWGDAM guidelines was completed for the…”
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Rapid multiplex DNA amplification on an inexpensive microdevice for human identification via short tandem repeat analysis
Published in Analytica chimica acta (08-08-2017)“…Forensic DNA analysis requires several steps, including DNA extraction, PCR amplification, and separation of PCR fragments. Intuitively, there are numerous…”
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Tumor aggressiveness is independent of radiation quality in murine hepatocellular carcinoma and mammary tumor models
Published in International journal of radiation biology (03-08-2021)“…Estimating cancer risk associated with interplanetary space travel is complicated. Human exposure data to high atomic number, high-energy (HZE) radiation is…”
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Retraction notice to “Developmental validation of the VersaPlex™ 27PY system” [Forensic Sci. Int. Rep. 2C (2020) 100156]
Published in Forensic Science International. Reports (01-07-2023)“…This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal)…”
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Concordance and population studies along with stutter and peak height ratio analysis for the PowerPlex® ESX 17 and ESI 17 Systems
Published in Forensic science international : genetics (01-08-2011)“…Abstract The PowerPlex® ESX 17 and ESI 17 Systems for short tandem repeat (STR) amplification were developed by the Promega Corporation to meet the European…”
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Protein–protein interaction studies on protein arrays: Effect of detection strategies on signal-to-background ratios
Published in Analytical biochemistry (01-09-2009)“…Protein arrays hold great promise for proteome-scale analysis of protein–protein interaction networks, but the technical challenges have hindered their…”
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