Search Results - "Storti, Paola"

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target by Bolzoni, Marina, Chiu, Martina, Accardi, Fabrizio, Vescovini, Rosanna, Airoldi, Irma, Storti, Paola, Todoerti, Katia, Agnelli, Luca, Missale, Gabriele, Andreoli, Roberta, Bianchi, Massimiliano G., Allegri, Manfredi, Barilli, Amelia, Nicolini, Francesco, Cavalli, Albertina, Costa, Federica, Marchica, Valentina, Toscani, Denise, Mancini, Cristina, Martella, Eugenia, Dall'Asta, Valeria, Donofrio, Gaetano, Aversa, Franco, Bussolati, Ovidio, Giuliani, Nicola

“…The importance of glutamine (Gln) metabolism in multiple myeloma (MM) cells and its potential role as a therapeutic target are still unknown, although it has…”
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Role of Galectins in Multiple Myeloma by Storti, Paola, Marchica, Valentina, Giuliani, Nicola

“…Galectins are a family of lectins that bind β-galactose-containing glycoconjugates and are characterized by carbohydrate-recognition domains (CRDs). Galectins…”
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Oncolytic viruses: a potential breakthrough immunotherapy for multiple myeloma patients by Raimondi, Vincenzo, Vescovini, Rosanna, Dessena, Mattia, Donofrio, Gaetano, Storti, Paola, Giuliani, Nicola

“…Oncolytic virotherapy represents an innovative and promising approach for the treatment of cancer, including multiple myeloma (MM), a currently incurable…”
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ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma by Marchesini, Matteo, Ogoti, Yamini, Fiorini, Elena, Aktas Samur, Anil, Nezi, Luigi, D'Anca, Marianna, Storti, Paola, Samur, Mehmet Kemal, Ganan-Gomez, Irene, Fulciniti, Maria Teresa, Mistry, Nipun, Jiang, Shan, Bao, Naran, Marchica, Valentina, Neri, Antonino, Bueso-Ramos, Carlos, Wu, Chang-Jiun, Zhang, Li, Liang, Han, Peng, Xinxin, Giuliani, Nicola, Draetta, Giulio, Clise-Dwyer, Karen, Kantarjian, Hagop, Munshi, Nikhil, Orlowski, Robert, Garcia-Manero, Guillermo, DePinho, Ronald A., Colla, Simona

“…Amplification of 1q21 occurs in approximately 30% of de novo and 70% of relapsed multiple myeloma (MM) and is correlated with disease progression and drug…”
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CD14+CD16+ monocytes are involved in daratumumab‐mediated myeloma cells killing and in anti‐CD47 therapeutic strategy by Storti, Paola, Vescovini, Rosanna, Costa, Federica, Marchica, Valentina, Toscani, Denise, Dalla Palma, Benedetta, Craviotto, Luisa, Malavasi, Fabio, Giuliani, Nicola

“…Summary A deep elucidation of the mechanisms of action of anti‐CD38 monoclonal antibodies (mAbs), such as daratumumab (DARA), is required to identify patients…”
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Molecular Features of the Mesenchymal and Osteoblastic Cells in Multiple Myeloma by Iannozzi, Nicolas Thomas, Marchica, Valentina, Toscani, Denise, Burroughs Garcìa, Jessica, Giuliani, Nicola, Storti, Paola

“…Multiple myeloma (MM) is a monoclonal gammopathy characterized by biological heterogeneity and unregulated proliferation of plasma cells (PCs) in bone marrow…”
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Identification of PSMB4 and PSMD4 as novel target genes correlated with 1q21 amplification in patients with smoldering myeloma and multiple myeloma by Garcia, Jessica Burroughs, Storti, Paola, Iannozzi, Nicolas Thomas, Marchica, Valentina, Agnelli, Luca, Toscani, Denise, Franceschi, Valentina, Todaro, Giannalisa, Sammarelli, Gabriella, Notarfranchi, Laura, Scita, Matteo, Palma, Benedetta Dalla, Raimondi, Vincenzo, Lungu, Oxana, Pruneri, Giancarlo, Donofrio, Gaetano, Giuliani, Nicola

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Metabolic features of myeloma cells in the context of bone microenvironment: Implication for the pathophysiology and clinic of myeloma bone disease by Raimondi, Vincenzo, Toscani, Denise, Marchica, Valentina, Burroughs-Garcia, Jessica, Storti, Paola, Giuliani, Nicola

“…Multiple myeloma (MM) is a hematological malignancy characterized by the accumulation of malignant plasma cells (PCs) into the bone marrow (BM). The complex…”
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CD38 expression by plasma cells in extramedullary multiple myeloma by Notarfranchi, Laura, Accardi, Fabrizio, Mancini, Cristina, Martella, Eugenia, Bonomini, Sabrina, Segreto, Roberta, Vescovini, Rosanna, Palma, Anna Benedetta Dalla, Sammarelli, Gabriella, Todaro, Giannalisa, Storti, Paola, Burroughs-Garcia, Jessica, Iannozzi, Nicolas Thomas, Raimondi, Vincenzo, Lungu, Oxana, Ricci, Stefania, Craviotto, Luisa, Giuliani, Nicola

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Mechanisms of Action of the New Antibodies in Use in Multiple Myeloma by Romano, Alessandra, Storti, Paola, Marchica, Valentina, Scandura, Grazia, Notarfranchi, Laura, Craviotto, Luisa, Di Raimondo, Francesco, Giuliani, Nicola

“…Monoclonal antibodies (mAbs) directed against antigen-specific of multiple myeloma (MM) cells have Fc-dependent immune effector mechanisms, such as…”
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Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma by Thongon, Natthakan, Ma, Feiyang, Baran, Natalia, Lockyer, Pamela, Liu, Jintan, Jackson, Christopher, Rose, Ashley, Furudate, Ken, Wildeman, Bethany, Marchesini, Matteo, Marchica, Valentina, Storti, Paola, Todaro, Giannalisa, Ganan-Gomez, Irene, Adema, Vera, Rodriguez-Sevilla, Juan Jose, Qing, Yun, Ha, Min Jin, Fonseca, Rodrigo, Stein, Caleb, Class, Caleb, Tan, Lin, Attanasio, Sergio, Garcia-Manero, Guillermo, Giuliani, Nicola, Berrios Nolasco, David, Santoni, Andrea, Cerchione, Claudio, Bueso-Ramos, Carlos, Konopleva, Marina, Lorenzi, Philip, Takahashi, Koichi, Manasanch, Elisabet, Sammarelli, Gabriella, Kanagal-Shamanna, Rashmi, Viale, Andrea, Chesi, Marta, Colla, Simona

“…DNA damage resistance is a major barrier to effective DNA-damaging therapy in multiple myeloma (MM). To discover mechanisms through which MM cells overcome DNA…”
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Immune response to SARS-CoV-2 mRNA vaccination and booster dose in patients with multiple myeloma and monoclonal gammopathies: impact of Omicron variant on the humoral response by Storti, Paola, Marchica, Valentina, Vescovini, Rosanna, Franceschi, Valentina, Russo, Luca, Notarfranchi, Laura, Raimondi, Vincenzo, Toscani, Denise, Burroughs Garcia, Jessica, Costa, Federica, Dalla Palma, Benedetta, Iannozzi, Nicolas Thomas, Sammarelli, Gabriella, Donofrio, Gaetano, Giuliani, Nicola

“…The humoral and cellular response to SARS-CoV-2 mRNA full vaccination and booster dose as well as the impact of the spike variants, including Omicron, are…”
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PD-L1/PD-1 Pattern of Expression Within the Bone Marrow Immune Microenvironment in Smoldering Myeloma and Active Multiple Myeloma Patients by Costa, Federica, Vescovini, Rosanna, Marchica, Valentina, Storti, Paola, Notarfranchi, Laura, Dalla Palma, Benedetta, Toscani, Denise, Burroughs-Garcia, Jessica, Catarozzo, Maria Teresa, Sammarelli, Gabriella, Giuliani, Nicola

“…The PD-1/PD-L1 axis has recently emerged as an immune checkpoint that controls antitumor immune responses also in hematological malignancies. However, the use…”
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The transcriptomic profile of CD138 + cells from patients with early progression from smoldering to active multiple myeloma remains substantially unchanged by Storti, Paola, Agnelli, Luca, Palma, Benedetta Dalla, Todoerti, Katia, Marchica, Valentina, Accardi, Fabrizio, Sammarelli, Gabriella, Deluca, Federica, Toscani, Denise, Costa, Federica, Vicario, Emanuela, Todaro, Giannalisa, Martella, Eugenia, Neri, Antonino, Giuliani, Nicola

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Interleukin-27 Acts as Multifunctional Antitumor Agent in Multiple Myeloma by COCCO, Claudia, GIULIANI, Nicola, DI CARLO, Emma, OGNIO, Emanuela, STORTI, Paola, ABELTINO, Manuela, SORRENTINO, Carlo, PONZONI, Maurilio, RIBATTI, Domenico, AIROLDI, Irma

“…Multiple myeloma (MM) derives from plasmablast/plasma cells that accumulate in the bone marrow. Different microenvironmental factors may promote metastatic…”
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Role of 1q21 in Multiple Myeloma: From Pathogenesis to Possible Therapeutic Targets by Burroughs Garcìa, Jessica, Eufemiese, Rosa Alba, Storti, Paola, Sammarelli, Gabriella, Craviotto, Luisa, Todaro, Giannalisa, Toscani, Denise, Marchica, Valentina, Giuliani, Nicola

“…Multiple myeloma (MM) is characterized by an accumulation of malignant plasma cells (PCs) in the bone marrow (BM). The amplification of 1q21 is one of the most…”
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IL21R expressing CD14 + CD16 + monocytes expand in multiple myeloma patients leading to increased osteoclasts by Bolzoni, Marina, Ronchetti, Domenica, Storti, Paola, Donofrio, Gaetano, Marchica, Valentina, Costa, Federica, Agnelli, Luca, Toscani, Denise, Vescovini, Rosanna, Todoerti, Katia, Bonomini, Sabrina, Sammarelli, Gabriella, Vecchi, Andrea, Guasco, Daniela, Accardi, Fabrizio, Palma, Benedetta Dalla, Gamberi, Barbara, Ferrari, Carlo, Neri, Antonino, Aversa, Franco, Giuliani, Nicola

“…Bone marrow monocytes are primarily committed to osteoclast formation. It is, however, unknown whether potential primary alterations are specifically present…”
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Bovine pestivirus is a new alternative virus for multiple myeloma oncolytic virotherapy by Marchica, Valentina, Franceschi, Valentina, Vescovini, Rosanna, Storti, Paola, Vicario, Emanuela, Toscani, Denise, Zorzoli, Alessia, Airoldi, Irma, Dalla Palma, Benedetta, Campanini, Nicoletta, Martella, Eugenia, Mancini, Cristina, Costa, Federica, Donofrio, Gaetano, Giuliani, Nicola

“…The oncolytic viruses have shown promising results for the treatment of multiple myeloma. However, the use of human viruses is limited by the patients'…”
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P830: IDENTIFICATION OF NOVEL TARGET GENES CORRELATED WITH 1Q21 AMPLIFICATION IN PATIENTS WITH SMOLDERING MYELOMA AND MULTIPLE MYELOMA by Thomas Iannozzi, Nicolas, Burroughs Garcia, Jessica, Storti, Paola, Toscani, Denise, Marchica, Valentina, Franceschi, Valentina, Agnelli, Luca, Raimondi, Vincenzo, Todaro, Giannalisa, Lungu, Oxana, Bernardi, Matia, Sammarelli, Gabriella, Donofrio, Gaetano, Dalla Palma, Benedetta, Giuliani, Nicola

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A personalized molecular approach in multiple myeloma: the possible use of RAF/RAS/MEK/ERK and BCL-2 inhibitors by Raimondi, Vincenzo, Iannozzi, Nicolas Thomas, Burroughs-Garcìa, Jessica, Toscani, Denise, Storti, Paola, Giuliani, Nicola

“…Multiple myeloma (MM) is a blood cancer that derives from plasma cells (PCs), which will accumulate in the bone marrow (BM). Over time, several drugs have been…”
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