Search Results - "Storm, Nadia J"

Hexosamine Pathway Metabolites Enhance Protein Quality Control and Prolong Life by Denzel, Martin S., Storm, Nadia J., Gutschmidt, Aljona, Baddi, Ruth, Hinze, Yvonne, Jarosch, Ernst, Sommer, Thomas, Hoppe, Thorsten, Antebi, Adam

“…Aging entails a progressive decline in protein homeostasis, which often leads to age-related diseases. The endoplasmic reticulum (ER) is the site of…”
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Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome by Bourdenx, Mathieu, Martín-Segura, Adrián, Scrivo, Aurora, Rodriguez-Navarro, Jose A., Kaushik, Susmita, Tasset, Inmaculada, Diaz, Antonio, Storm, Nadia J., Xin, Qisheng, Juste, Yves R., Stevenson, Erica, Luengo, Enrique, Clement, Cristina C., Choi, Se Joon, Krogan, Nevan J., Mosharov, Eugene V., Santambrogio, Laura, Grueninger, Fiona, Collin, Ludovic, Swaney, Danielle L., Sulzer, David, Gavathiotis, Evripidis, Cuervo, Ana Maria

“…Components of the proteostasis network malfunction in aging, and reduced protein quality control in neurons has been proposed to promote neurodegeneration…”
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A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy by Hernandez, Israel, Luna, Gabriel, Rauch, Jennifer N, Reis, Surya A, Giroux, Michel, Karch, Celeste M, Boctor, Daniel, Sibih, Youssef E, Storm, Nadia J, Diaz, Antonio, Kaushik, Susmita, Zekanowski, Cezary, Kang, Alexander A, Hinman, Cassidy R, Cerovac, Vesna, Guzman, Elmer, Zhou, Honjun, Haggarty, Stephen J, Goate, Alison M, Fisher, Steven K, Cuervo, Ana M, Kosik, Kenneth S

“…Tau inclusions are a shared feature of many neurodegenerative diseases, among them frontotemporal dementia caused by tau mutations. Treatment approaches for…”
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Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia by Geier, Ethan G., Bourdenx, Mathieu, Storm, Nadia J., Cochran, J. Nicholas, Sirkis, Daniel W., Hwang, Ji-Hye, Bonham, Luke W., Ramos, Eliana Marisa, Diaz, Antonio, Van Berlo, Victoria, Dokuru, Deepika, Nana, Alissa L., Karydas, Anna, Balestra, Maureen E., Huang, Yadong, Russo, Silvia P., Spina, Salvatore, Grinberg, Lea T., Seeley, William W., Myers, Richard M., Miller, Bruce L., Coppola, Giovanni, Lee, Suzee E., Cuervo, Ana Maria, Yokoyama, Jennifer S.

“…Pathogenic variation in MAPT , GRN , and C9ORF72 accounts for at most only half of frontotemporal lobar degeneration (FTLD) cases with a family history of…”
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Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype? by Ungvari, Zoltan, Sosnowska, Danuta, Mason, Jeffrey B, Gruber, Heike, Lee, Star W, Schwartz, Tonia S, Brown, Marishka K, Storm, Nadia J, Fortney, Kristen, Sowa, Jessica, Byrne, Alexandra B, Kurz, Tino, Levy, Erik, Sonntag, William E, Austad, Steven N, Csiszar, Anna, Ridgway, Iain

“…Bivalve molluscs are newly discovered models of successful aging. Here, we test the hypothesis that extremely long-lived bivalves are not uniquely resistant to…”
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