Search Results - "Storm, J. F."

General Anesthesia Disrupts Complex Cortical Dynamics in Response to Intracranial Electrical Stimulation in Rats by Arena, A., Comolatti, R., Thon, S., Casali, A. G., Storm, J. F.

“…The capacity of human brain to sustain complex cortical dynamics appears to be strongly associated with conscious experience and consistently drops when…”
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Cerebellar Ataxia and Purkinje Cell Dysfunction Caused by Ca2+-Activated K+Channel Deficiency by Sausbier, M., Hu, H., Arntz, C., Feil, S., Kamm, S., Adelsberger, H., Sausbier, U., Sailer, C. A., Feil, R., Hofmann, F., Korth, M., Shipston, M. J., H.-G. Knaus, Wolfer, D. P., Pedroarena, C. M., Storm, J. F., Ruth, P., Andersen, Per O.

“…Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance…”
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Kv7/KCNQ/M-channels in rat glutamatergic hippocampal axons and their role in regulation of excitability and transmitter release by Vervaeke, K., Gu, N., Agdestein, C., Hu, H., Storm, J. F.

“…M-current ( I M ) plays a key role in regulating neuronal excitability. Mutations in Kv7/KCNQ subunits, the molecular correlates of I M , are associated with a…”
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Two distinct pools of large-conductance calcium-activated potassium channels in the somatic plasma membrane of central principal neurons by Kaufmann, W.A, Kasugai, Y, Ferraguti, F, Storm, J.F

“…Abstract Although nerve cell membranes are often assumed to be uniform with respect to electrical properties, there is increasing evidence for…”
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Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells by Storm, J F

“…1. The repolarization of the action potential, and a fast after-hyperpolarization (a.h.p.) were studied in CA1 pyramidal cells (n = 76) in rat hippocampal…”
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Interaction between synaptic excitation and slow afterhyperpolarization current in rat hippocampal pyramidal cells by Lancaster, B., Hu, H., Ramakers, G. M. J., Storm, J. F.

“…Whole cell recordings from CA1 pyramidal cells were performed to investigate the interaction between excitatory postsynaptic potentials (EPSPs) or currents…”
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BK channel activity determines the extent of cell degeneration after oxygen and glucose deprivation: a study in organotypical hippocampal slice cultures by Rundén-Pran, E., Haug, F.M., Storm, J.F., Ottersen, O.P.

“…BK channels are voltage- and calcium-dependent potassium channels whose activation tends to reduce cellular excitability. In hippocampal pyramidal cells, BK…”
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An after-hyperpolarization of medium duration in rat hippocampal pyramidal cells by Storm, J F

“…1. In hippocampal pyramidal cells, action potentials are followed by three after-hyperpolarizations (AHPs): a fast AHP (fAHP) lasting 2-5 ms, a medium AHP…”
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Potassium currents in hippocampal pyramidal cells by Storm, J F

“…The hippocampal pyramidal cells provide an example of how multiple potassium (K) currents co-exist and function in central mammalian neurones. The data come…”
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PKA mediates the effects of monoamine transmitters on the K+ current underlying the slow spike frequency adaptation in hippocampal neurons by Pedarzani, P, Storm, J F

“…The Ca(2+)-activated K+ current IAHP, which underlies spike frequency adaptation in cortical pyramidal cells, can be modulated by multiple transmitters and…”
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Temporal integration by a slowly inactivating K + current in hippocampal neurons by Storm, Johan F

“…A central aspect of neuronal function is how each nerve cell translated synaptic input into a sequence of action potentials that carry information along the…”
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Capacity for consciousness under ketamine anaesthesia is selectively associated with activity in posteromedial cortex in rats by Arena, A, Juel, B E, Comolatti, R, Thon, S, Storm, J F

“…Abstract It remains unclear how specific cortical regions contribute to the brain’s overall capacity for consciousness. Clarifying this could help distinguish…”
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Protein Kinase A-Independent Modulation of Ion Channels in the Brain by Cyclic AMP by Pedarzani, Paola, Storm, Johan F.

“…Ion channels underlying the electrical activity of neurons can be regulated by neurotransmitters via two basic mechanisms: ligand binding and covalent…”
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K+ channels and their distribution in large cortical pyramidal neurones by Storm, J. F.

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Presynaptic Ca2+-Activated K+ Channels in Glutamatergic Hippocampal Terminals and Their Role in Spike Repolarization and Regulation of Transmitter Release by Hu, Hua, Shao, Li-Rong, Chavoshy, Sorush, Gu, Ning, Trieb, Maria, Behrens, Ralf, Laake, Petter, Pongs, Olaf, Knaus, Hans Gunther, Ottersen, Ole Petter, Storm, Johan F

“…Large-conductance Ca(2+)-activated K(+) channels (BK, also called Maxi-K or Slo channels) are widespread in the vertebrate nervous system, but their functional…”
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SK channels and the varieties of slow after-hyperpolarizations in neurons by Vogalis, Fivos, Storm, Johan F., Lancaster, Barrie

“…Action potentials and associated Ca2+ influx can be followed by slow after‐hyperpolarizations (sAHPs) caused by a voltage‐insensitive, Ca2+‐dependent K+…”
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Specificity of Protein Kinase Inhibitor Peptides and Induction of Long-Term Potentiation by Hvalby, Oivind, Hemmings, Hugh C., Paulsen, Ole, Czernik, Andrew J., Nairn, Angus C., Godfraind, Jean-Marie, Jensen, Vidar, Raastad, Morten, Storm, Johan F., Andersen, Per, Greengard, Paul

“…Previous studies have used synthetic peptide analogs, corresponding to sequences within the pseudosubstrate domain of protein kinase C (PKC) or the…”
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The role of BK-type Ca2+-dependent K+ channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells by Shao, Li‐Rong, Halvorsrud, Ragnhild, Borg‐Graham, Lyle, Storm, Johan F.

“…The role of large-conductance Ca 2+ -dependent K + channels (BK-channels; also known as maxi-K- or slo- channels) in spike broadening during repetitive firing…”
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Dopamine modulates the slow Ca(2+)-activated K+ current IAHP via cyclic AMP-dependent protein kinase in hippocampal neurons by Pedarzani, P, Storm, J F

“…1. The effects of dopamine on the slow Ca(2+)-dependent K+ current (IAHP; AHP, afterhyperpolarization) and spike frequency adaptation were studied by whole…”
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Functional and Molecular Aspects of Voltage-Gated K+ Channel β Subunits by PONGS, OLAF, LEICHER, THORSTEN, BERGER, MICHAELA, ROEPER, JOCHEN, BÄHRING, ROBERT, WRAY, DENNIS, GIESE, KARL PETER, SILVA, ALCINO J., STORM, JOHAN F.

“…Voltage‐gated potassium channels (Kv) of the Shaker‐related superfamily are assembled from membrane‐integrated α subunits and auxiliary β subunits. The β…”
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