Search Results - "Storm, D. R."

Constitutive μ-Opioid Receptor Activity Leads to Long-Term Endogenous Analgesia and Dependence by Corder, G., Doolen, S., Donahue, R. R., Winter, M. K., Jutras, B. L., He, Y., Hu, X., Wieskopf, J. S., Mogil, J. S., Storm, D. R., Wang, Z. J., McCarson, K. E., Taylor, B. K.

“…Opioid receptor antagonists increase hyperalgesia in humans and animals, which indicates that endogenous activation of opioid receptors provides relief from…”
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Inactivation of the Mouse Adenylyl Cyclase 3 Gene Disrupts Male Fertility and Spermatozoon Function by Livera, G, Xie, F, Garcia, M. A, Jaiswal, B, Chen, J, Law, E, Storm, D. R, Conti, M

“…Mammalian spermatids and spermatozoa express functional G protein-coupled receptors. However, bicarbonate-regulated soluble adenylyl cyclase (AC), the major AC…”
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Inactivation of Pde8b enhances memory, motor performance, and protects against age‐induced motor coordination decay by Tsai, L.‐C. L., Chan, G. C.‐K., Nangle, S. N., Shimizu‐Albergine, M., Jones, G. L., Storm, D. R., Beavo, J. A., Zweifel, L. S.

“…Phosphodiesterase 8B is enriched in select brain regions and regulates learning, memory, and motor coordination. Phosphodiesterases (PDEs) are critical…”
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Ca2+/calmodulin binds to and modulates P/Q-type calcium channels by LEE, A, WONG, S. T, GALLAGHER, D, BIN LI, STORM, D. R, SCHEUER, T, CATTERALL, W. A

“…Neurotransmitter release at many central synapses is initiated by an influx of calcium ions through P/Q-type calcium channels, which are densely localized in…”
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Bidirectional synaptic plasticity and spatial memory flexibility require Ca2+-stimulated adenylyl cyclases by Zhang, Ming, Storm, Daniel R, Wang, Hongbing

“…When certain memory becomes obsolete, effective suppression of the previously established memory is essential for animals to adapt to the changing environment…”
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The diurnal oscillation of MAP (mitogen-activated protein) kinase and adenylyl cyclase activities in the hippocampus depends on the suprachiasmatic nucleus by Phan, Trongha X, Phan, Trongha H, Chan, Guy C-K, Sindreu, Carlos B, Eckel-Mahan, Kristin L, Storm, Daniel R

“…Consolidation of hippocampus-dependent memory is dependent on activation of the cAMP/Erk/MAPK (mitogen-activated protein kinase) signal transduction pathway in…”
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Altered Behavior and Long-Term Potentiation in Type I Adenylyl Cyclase Mutant Mice by Wu, Zhi-Liang, Thomas, Steven A., Villacres, Enrique C., Xia, Zhengui, Simmons, Michele L., Chavkin, Charles, Palmiter, Richard D., Storm, Daniel R.

“…The murine Ca2+-stimulated adenylyl cyclase (type I) (EC 4.6.1.1), which is expressed predominantly in brain, was inactivated by targeted mutagenesis…”
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Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex by Schalkwyk, Leonard C, Neumann, Paul E, Guernsey, Duane L, Smallman, Donald S, Wong, Scott T, Storm, Daniel R, Fine, Alan, Leong, Wey L, Abdel-Majid, Raja M, Dobson, Melanie J

“…The somatosensory (SI) cortex of mice displays a patterned, nonuniform distribution of neurons in layer IV called the 'barrelfield' (ref. 1). Thalamocortical…”
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Identification and characterization of the calmodulin-binding domain of neuromodulin, a neurospecific calmodulin-binding protein by Alexander, K A, Wakim, B T, Doyle, G S, Walsh, K A, Storm, D R

“…Neuromodulin (formerly designated P-57) is an abundant, neural specific, calmodulin-binding protein which exhibits higher affinity for calmodulin in the…”
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Characterization of the calmodulin binding domain of neuromodulin. Functional significance of serine 41 and phenylalanine 42 by Chapman, E R, Au, D, Alexander, K A, Nicolson, T A, Storm, D R

“…Neuromodulin (also designated P-57, GAP-43, B-50) is a major presynaptic substrate for protein kinase C. Phosphorylation of neuromodulin decreases its affinity…”
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Dephosphorylation of Neuromodulin by Calcineurin by Liu, Y C, Storm, D R

“…Neuromodulin (p57, GAP-43, F1, B-50) is a major neural-specific, calmodulin binding protein found in brain, spinal cord, and retina that is associated with…”
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Regulation of calmodulin binding to P-57. A neurospecific calmodulin binding protein by Alexander, K.A., Cimler, B.M., Meier, K.E., Storm, D.R.

“…P-57 is a neural-specific calmodulin binding protein with novel calmodulin binding properties. P-57 exhibits higher affinity for calmodulin-Sepharose in the…”
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Stimulation of the type III olfactory adenylyl cyclase by calcium and calmodulin by Choi, Eui-Ju, Xia, Zhengui, Storm, Daniel R

“…Characterization of adenylyl cyclases has been facilitated by the isolation of cDNA clones for distinct adenylyl cyclases including the type I and type III…”
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Oxidation of critical cysteine residues of type I adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin by DUHE, R. J, NIELSEN, M. D, DITTMAN, A. H, VILLACRES, E. C, EUI-JU CHOI, STORM, D. R

“…The calmodulin binding domain of the type I adenylyl cyclase has recently been identified as an amino acid sequence (residues 495-522) that contains 2 cysteine…”
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Making New Connections: Role of ERK/MAP Kinase Signaling in Neuronal Plasticity by Impey, Soren, Obrietan, Karl, Storm, Daniel R

“…One of the most intriguing questions in neurobiology is how neurons and synapses encode the long-term changes in synaptic efficacy that underlie memory…”
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Regulation of type I adenylyl cyclase by calmodulin kinase IV in vivo by Wayman, Gary A., Wei, Jia, Wong, Scott, Storm, Daniel R.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Calcium and muscarinic agonist stimulation of type I adenylylcyclase in whole cells by EUI-JU CHOI, WONG, S. T, HINDS, T. R, STORM, D. R

“…The type I adenylylcyclase which was originally purified and cloned from bovine brain is stimulated by Ca2+ and calmodulin in vitro. Although it has been…”
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Distribution of mRNA for the calmodulin-sensitive adenylate cyclase in rat brain: expression in areas associated with learning and memory by Xia, Z G, Refsdal, C D, Merchant, K M, Dorsa, D M, Storm, D R

“…The Drosophila learning mutant, rutabaga, is deficient in the calmodulin-sensitive adenylate cyclase, and studies of associative learning in Aplysia have…”
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Intracellular sorting of neuromodulin (GAP-43) mutants modified in the membrane targeting domain by Liu, Y, Fisher, DA, Storm, DR

“…Neuromodulin (GAP-43) is a neurospecific calmodulin binding protein that is targeted to neuronal growth cones via fast axonal transport by an undefined…”
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Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei by Storm, Daniel R, Obrietan, Karl, Impey, Soren

“…Although the circadian time-keeping properties of the suprachiasmatic nuclei (SCN) require gene expression, little is known about the signal transduction…”
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