Search Results - "Storci, G."

basal-like breast carcinoma phenotype is regulated by SLUG gene expression by Storci, G, Sansone, P, Trere, D, Tavolari, S, Taffurelli, M, Ceccarelli, C, Guarnieri, T, Paterini, P, Pariali, M, Montanaro, L, Santini, D, Chieco, P, Bonafé, M

“…Basal-like breast carcinoma is an aggressive form of breast cancer, characterized by the absence of oestrogen receptor and HER2 expression, the presence of…”
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Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells by Papi, A, Guarnieri, T, Storci, G, Santini, D, Ceccarelli, C, Taffurelli, M, De Carolis, S, Avenia, N, Sanguinetti, A, Sidoni, A, Orlandi, M, Bonafé, M

“…Recent literature highlights the importance of pro-inflammatory cytokines in the biology of breast cancer stem cells (CSCs), unraveling differences with…”
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Predicting ICANS by means of plasma CAR‐T cell derived extracellular vesicles in patients undergoing infusion of anti‐CD19 CAR‐T cells by Felice, F., Storci, G., Ricci, F., Tazzari, P. L., Matteis, S., Bertuccio, S. N., Rossini, L., Tomassini, E., Dicataldo, M., Laprovitera, N., Barbato, F., Ursi, M., Messelodi, D., Cortelli, P., Guarino, M., Maffini, E., Roberto, M., Dan, E., Sinigaglia, B., Santi, S., Ferracin, M., Pellegrini, C., Stefoni, V., Guadagnuolo, S., Casadei, B., Zinzani, P. L., Bonafe, M., Bonifazi, F.

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Isolation of stem/progenitor cells from normal lung tissue of adult humans by Tesei, A. , Zoli, W. , Arienti, C. , Storci, G. , Granato, A. M. , Pasquinelli, G. , Valente, S. , Orrico, C. , Rosetti, M. , Vannini, I. , Dubini, A. , Dell'Amore, D. , Amadori, D. , Bonafè, M. 

“…Objectives:  This study aimed to isolate and characterize stem/progenitor cells, starting from normal airway epithelia, obtained from human adults. Materials…”
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The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death by Bonafé, M, Salvioli, S, Barbi, C, Trapassi, C, Tocco, F, Storci, G, Invidia, L, Vannini, I, Rossi, M, Marzi, E, Mishto, M, Capri, M, Olivieri, F, Antonicelli, R, Memo, M, Uberti, D, Nacmias, B, Sorbi, S, Monti, D, Franceschi, C

“…A common arginine to proline polymorphism is harboured at codon 72 of the human p53 gene. In this investigation, we found that fibroblasts and lymphocytes…”
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The p53 codon 72 proline allele is endowed with enhanced cell-death inducing potential in cancer cells exposed to hypoxia by SANSONE, P, STORCI, G, PANDOLFI, S, MONTANARO, L, CHIECO, P, BONAFE, M

“…The preferential retention of the arginine allele at the p53 codon 72 locus is commonly observed in tumours from arginine/proline heterozygotes. Considering…”
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Role of p53 codon 72 arginine allele in cell survival in vitro and in the clinical outcome of patients with advanced breast cancer by Vannini, I, Zoli, W, Tesei, A, Rosetti, M, Sansone, P, Storci, G, Passardi, A, Massa, I, Ricci, M, Gusolfino, D, Fabbri, F, Ulivi, P, Brigliadori, G, Amadori, D, Bonafe, M

“…The p53 codon 72 polymorphism, which results in either an arginine or proline residue, plays a different role in vitro and in vivo in cell survival and drug…”
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Apoptosis-resistant phenotype in HL-60-derived cells HCW-2 is related to changes in expression of stress-induced proteins that impact on redox status and mitochondrial metabolism by Salvioli, S, Storci, G, Pinti, M, Quaglino, D, Moretti, L, Merlo-Pich, M, Lenaz, G, Filosa, S, Fico, A, Bonafè, M, Monti, D, Troiano, L, Nasi, M, Cossarizza, A, Franceschi, C

“…The onset of resistance to drug-induced apoptosis of tumour cells is a major problem in cancer therapy. We studied a drug-selected clone of promyelocytic HL-60…”
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The role of extracellular DNA in COVID-19: Clues from inflamm-aging by Storci, Gianluca, Bonifazi, Francesca, Garagnani, Paolo, Olivieri, Fabiola, Bonafè, Massimiliano

“…•The concept of inflamm-aging can help to better understand the potent inflammatory response produced by COVID-19.•The age associated imbalance between…”
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Aging and Caloric Restriction Modulate the DNA Methylation Profile of the Ribosomal RNA Locus in Human and Rat Liver by Gensous, Noémie, Ravaioli, Francesco, Pirazzini, Chiara, Gramignoli, Roberto, Ellis, Ewa, Storci, Gianluca, Capri, Miriam, Strom, Stephen, Laconi, Ezio, Franceschi, Claudio, Garagnani, Paolo, Marongiu, Fabio, Bacalini, Maria Giulia

“…A growing amount of evidence suggests that the downregulation of protein synthesis is an adaptive response during physiological aging, which positively…”
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Glutathione transferase-A2 S112T polymorphism predicts survival, transplant-related mortality, busulfan and bilirubin blood levels after allogeneic stem cell transplantation by Bonifazi, Francesca, Storci, Gianluca, Bandini, Giuseppe, Marasco, Elena, Dan, Elisa, Zani, Elena, Albani, Fiorenzo, Bertoni, Sara, Bontadini, Andrea, De Carolis, Sabrina, Sapienza, Maria Rosaria, Rizzi, Simonetta, Motta, Maria Rosa, Ferioli, Martina, Garagnani, Paolo, Cavo, Michele, Mantovani, Vilma, Bonafè, Massimiliano

“…Busulfan liver metabolism depends on glutathione, a crucial mediator of cellular and systemic stress. Here we investigated 40 polymorphisms at 27 loci involved…”
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Retention of the p53 Codon 72 Arginine Allele Is Associated with a Reduction of Disease-Free and Overall Survival in Arginine/Proline Heterozygous Breast Cancer Patients by BONAFE, Massimiliano, CECCARELLI, Claudio, FRANCESCHI, Claudio, FARABEGOLI, Fulvia, SANTINI, Donatella, TAFFURELLI, Mario, BARBI, Cristiana, MARZI, Erika, TRAPASSI, Chiara, STORCI, Gianluca, OLIVIERI, Fabiola

“…Purpose: The arginine to proline substitution at codon 72 represents a common aminoacidic polymorphism of the p53 protein. Recent data suggest that p53 codon…”
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p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes by Bonafè, Massimiliano, Salvioli, Stefano, Barbi, Cristiana, Mishto, Michele, Trapassi, Chiara, Gemelli, Claudia, Storci, Gianluca, Olivieri, Fabiola, Monti, Daniela, Franceschi, Claudio

“…A wide difference in the susceptibility to undergo in vitro apoptosis exists among individuals, and this fact has potential implications in predicting the in…”
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What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians by Bonafè, Massimiliano, Barbi, Cristiana, Storci, Gianluca, Salvioli, Stefano, Capri, Miriam, Olivieri, Fabiola, Valensin, Silvana, Monti, Daniela, Gonos, Efstathios S, De Benedictis, Giovanna, Franceschi, Claudio

“…Centenarians are people who escaped from major common diseases, including cancer, and reached the extreme limits of human life-span. The analysis of…”
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