Search Results - "Stoppelli, M P"

Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma by ZANNETTI, A, DEL VECCHIO, S, CARRIERO, M. V, FONTI, R, FRANCO, P, BOTTI, G, D'AIUTO, G, STOPPELLI, M. P, SALVATORE, M

“…The regulatory mechanisms underlying the overexpression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in highly invasive breast…”
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The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases by Appella, E., Robinson, E.A., Ullrich, S.J., Stoppelli, M.P., Corti, A., Cassani, G., Blasi, F.

“…Previous studies have shown that the region of human urokinase-type plasminogen activator (uPA) responsible for receptor binding resides in the amino-terminal…”
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Differentiation-Enhanced Binding of the Amino-Terminal Fragment of Human Urokinase Plasminogen Activator to a Specific Receptor on U937 Monocytes by Stoppelli, M. Patrizia, Corti, Angelo, Soffientini, Adolfo, Cassani, Giovanni, Blasi, Francesco, Assoian, Richard K.

“…The purified amino-terminal fragment (ATF) of human urokinase plasminogen activator (residues 1-135), which is not required for activation of plasminogen,…”
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Identification and Primary Sequence of an Unspliced Human Urokinase Poly(A)+RNA by Verde, Pasquale, Stoppelli, M. Patrizia, Galeffi, Patrizia, Di Nocera, Pierpaolo, Blasi, Francesco

“…Human urokinase cDNA clones have been identified from a cDNA library prepared from total RNA of human fibroblasts transformed by simian virus 40 [Okayama, H. &…”
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Vitronectin binding to urokinase receptor in human breast cancer by Carriero, M V, Del Vecchio, S, Franco, P, Potena, M I, Chiaradonna, F, Botti, G, Stoppelli, M P, Salvatore, M

“…Functional assembly of the plasminogen-dependent proteolytic system on the cell surface requires multiple interactions involving urokinase (uPA), urokinase…”
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Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography : comparison with urokinase levels by DEL VECCHIO, S, STOPPELLI, M. P, SALVATORE, M, CARRIERO, M. V, FONTI, R, MASSA, O, PEI YONG LI, BOTTI, G, CERRA, M, D'AIUTO, G, ESPOSITO, G

“…We measured the tissue concentration of human urokinase receptor (uPAR) in 22 breast carcinomas and 9 benign breast lesions using in vitro quantitative…”
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Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies by CARRIERO, M. V, FRANCO, P, DEL VECCHIO, S, MASSA, O, BOTTI, G, D'AIUTO, G, STOPPELLI, M. P, SALVATORE, M

“…Current evidence regarding the regulation of urokinase-dependent extracellular proteolysis indicates that plasminogen activation is a surface-associated…”
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Regulation of Urokinase Receptors in Monocytelike U937 Cells by Phorbol Ester Phorbol Myristate Acetate by Picone, R., Kajtaniak, E. L., Nielsen, L. S., Behrendt, N., Mastronicola, M. R., Cubellis, M. V., Stoppelli, M. P., Pedersen, S., Danø, K., Blasi, F.

“…A specific surface receptor for urokinase plasminogen activator (uPA) recognizes the amino-terminal growth factor-like sequence of uPA, a region independent…”
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The soluble form of urokinase receptor promotes angiogenesis through its Ser88‐Arg‐Ser‐Arg‐Tyr92 chemotactic sequence by BIFULCO, K., LONGANESI‐CATTANI, I., GALA, M., DI CARLUCCIO, G., MASUCCI, M. T., PAVONE, V., LISTA, L., ARRA, C., STOPPELLI, M. P., CARRIERO, M. V.

“…Background: The urokinase plasminogen activator receptor (u‐PAR) focuses the proteolytic activity of the urokinase plasminogen activator (u‐PA) on the…”
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Separation and characterization of nonphosphorylated and serine-phosphorylated urokinase. Catalytic properties and sensitivity to plasminogen activator inhibitor type 1 by Franco, P, Mastronicola, M R, De Cesare, D, Nolli, M L, Wun, T C, Verde, P, Blasi, F, Stoppelli, M P

“…Urokinase synthesized by human A431 epidermoid carcinoma cells is phosphorylated on serine (Mastronicola, M. R., Stoppelli, M. P., Migliaccio, A., Auricchio,…”
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Increase in Urokinase Plasminogen Activator mRNA Synthesis in Human Carcinoma Cells Is a Primary Effect of the Potent Tumor Promoter, Phorbol Myristate Acetate by Stoppelli, M. Patrizia, Verde, Pasquale, Grimaldi, Giovanna, Locatelli, Elzbieta K., Blasi, Francesco

“…The effect of tumor promoters and growth factors on the synthesis of urokinase and urokinase mRNA in human carcinoma cells has been investigated. In…”
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Developmental regulation of an insulin-degrading enzyme from Drosophila melanogaster by Stoppelli, M.P, Garcia, J.V, Decker, S.J, Rosner, M.R

“…The precise mechanism by which insulin is degraded in mammalian cells is not presently known. Several lines of evidence suggest that degradation is initiated…”
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An Insulin Epidermal Growth Factor-Binding Protein from Drosophila Has Insulin-Degrading Activity by Garcia, J. Victor, Stoppelli, M. Patrizia, Decker, Stuart J., Rosner, Marsha Rich

“…We have recently described the purification and characterization of an insulin-degrading enzyme (IDE) from Drosophila melanogaster that can cleave porcine…”
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Urokinase receptor-dependent and -independent p56/59(hck) activation state is a molecular switch between myelomonocytic cell motility and adherence by Chiaradonna, F, Fontana, L, Iavarone, C, Carriero, M V, Scholz, G, Barone, M V, Stoppelli, M P

“…Anchorage-independent myelomonocytic cells acquire adherence within minutes of differentiation stimuli, such as the proteolytically inactive N-terminal…”
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Characterization of a Drosophila protein that binds both epidermal growth factor and insulin-related growth factors by Garcia, J.V, Stoppelli, M.P, Thompson, K.L, Decker, S.J, Rosner, M.R

“…The identification of a novel protein from Drosophila melanogaster that binds both mammalian epidermal growth factor (EGF) and insulin has been reported…”
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Serine phosphorylation of biosynthetic pro-urokinase from human tumor cells by Mastronicola, M.Rosaria, Stoppelli, M.Patrizia, Migliaccio, Antimo, Auricchio, Ferdinando, Blasi, Francesco

“…Phosphorylation is a potent mechanism regulating the activity of many intracellular enzymes. We have discovered that the product of the human urokinase…”
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Autocrine saturation of pro-urokinase receptors on human A431 cells by Stoppelli, M P, Tacchetti, C, Cubellis, M V, Corti, A, Hearing, V J, Cassani, G, Appella, E, Blasi, F

“…Single-chain pro-urokinase (pro-uPA) is present both in the medium and lysate of the A431 epidermoid carcinoma cell line. Most of the cell-associated pro-uPA…”
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In vitro receptor imaging for characterization of human solid tumors by Del Vecchio, S, Stoppelli, M P, Carriero, M V, Fonti, R, Massa, O, Li, P Y, Botti, G, Cerra, M, D'Aiuto, G, Esposito, G

“…Since many of the factors involved in tumor growth and progression act through a receptor-mediated mechanism, we applied in vitro receptor imaging techniques…”
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Transcriptional induction of urokinase in cultured human kidney carcinoma cells by tetradecanoyl-phorbol-acetate by Ferraiuolo, R, Stoppelli, M P, Verde, P, Bullock, S, Lazzaro, P, Blasi, F, Pietropaolo, T C

“…A cell line derived from a human kidney carcinoma produces in vitro the urinary type of plasminogen activator (urokinase). The synthesis of plasminogen…”
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Protein kinase C-dependent in vivo phosphorylation of prourokinase leads to the formation of a receptor competitive antagonist by Franco, P, Massa, O, Garcia-Rocha, M, Chiaradonna, F, Iaccarino, C, Correas, I, Mendez, E, Avila, J, Blasi, F, Stoppelli, M P

“…We recently reported that in vivo phosphorylation of urokinase-type plasminogen activator on Ser138/303 prevents its catalytic-independent ability to promote…”
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