Search Results - "Stoorvogel, W."

Dendritic cells release exosomes together with phagocytosed pathogen; potential implications for the role of exosomes in antigen presentation by Lindenbergh, Marthe F. S., Wubbolts, Richard, Borg, Ellen G. F., van 'T Veld, Esther M., Boes, Marianne, Stoorvogel, W.

“…Dendritic cells (DC) have the unique capacity to activate naïve T cells by presenting T cell receptor specific peptides from exogenously acquired antigens…”
Get full text

Exosome: from internal vesicle of the multivesicular body to intercellular signaling device by Denzer, K, Kleijmeer, M J, Heijnen, H F, Stoorvogel, W, Geuze, H J

“…Exosomes are small membrane vesicles that are secreted by a multitude of cell types as a consequence of fusion of multivesicular late endosomes/lysosomes with…”
Get full text

B lymphocytes secrete antigen-presenting vesicles by Raposo, G, Nijman, H W, Stoorvogel, W, Liejendekker, R, Harding, C V, Melief, C J, Geuze, H J

“…Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II-enriched compartment), that…”
Get full text

Identification of genes targeted by FSH and oocytes in porcine granulosa cells by Verbraak, E.J.C, van 't Veld, E.M, Groot Koerkamp, M, Roelen, B.A.J, van Haeften, T, Stoorvogel, W, Zijlstra, C

“…Abstract In the mammalian ovarian follicle maturing oocytes are nurtured and supported by surrounding somatic cells, the mural granulosa cells and the cumulus…”
Get full text

A method for immediate comparative assessment of microinjected mammalian oocytes by Hölzenspies, J.J., Stoorvogel, W., Colenbrander, B., Roelen, B.A.J., Haeften, T.van

“…Manipulation of mammalian oocytes at the molecular level is hampered by low transcriptional activity and the presence of large stores of mRNA and protein…”
Get full text

Insulin recruits GLUT4 from specialized VAMP2-carrying vesicles as well as from the dynamic endosomal/trans-Golgi network in rat adipocytes by Ramm, G, Slot, J W, James, D E, Stoorvogel, W

“…Insulin treatment of fat cells results in the translocation of the insulin-responsive glucose transporter type 4, GLUT4, from intracellular compartments to the…”
Get full text

MHC class II antigen presentation by dendritic cells regulated through endosomal sorting by ten Broeke, Toine, Wubbolts, Richard, Stoorvogel, Willem

“…For the initiation of adaptive immune responses, dendritic cells present antigenic peptides in association with major histocompatibility complex class II…”
Get full text

Differences in the Endosomal Distributions of the Two Mannose 6-Phosphate Receptors by Klumperman, Judith, Hille, Annette, Veenendaal, Tineke, Oorschot, Viola, Stoorvogel, Willem, von Figura, Kurt, Geuze, Hans J.

“…Multiple immunolabeling of cryosections was performed to compare the subcellular distributions of the two mannose 6-phosphate receptors (MPRs) involved in the…”
Get full text

Differential effects of brefeldin A on transport of secretory and lysosomal proteins by STROUS, G. J, VAN KERKHOF, P, VAN MEER, G, RIJNBOUTT, S, STOORVOGEL, W

“…Brefeldin A (BFA) rapidly blocks anterograde exocytotic transport through the Golgi complex. Sustained retrograde traffic induced by brefeldin A causes…”
Get full text

Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation by Kalra, Hina, Simpson, Richard J, Ji, Hong, Aikawa, Elena, Altevogt, Peter, Askenase, Philip, Bond, Vincent C, Borràs, Francesc E, Breakefield, Xandra, Budnik, Vivian, Buzas, Edit, Camussi, Giovanni, Clayton, Aled, Cocucci, Emanuele, Falcon-Perez, Juan M, Gabrielsson, Susanne, Gho, Yong Song, Gupta, Dwijendra, Harsha, H C, Hendrix, An, Hill, Andrew F, Inal, Jameel M, Jenster, Guido, Krämer-Albers, Eva-Maria, Lim, Sai Kiang, Llorente, Alicia, Lötvall, Jan, Marcilla, Antonio, Mincheva-Nilsson, Lucia, Nazarenko, Irina, Nieuwland, Rienk, Nolte-'t Hoen, Esther N M, Pandey, Akhilesh, Patel, Tushar, Piper, Melissa G, Pluchino, Stefano, Prasad, T S Keshava, Rajendran, Lawrence, Raposo, Graca, Record, Michel, Reid, Gavin E, Sánchez-Madrid, Francisco, Schiffelers, Raymond M, Siljander, Pia, Stensballe, Allan, Stoorvogel, Willem, Taylor, Douglas, Thery, Clotilde, Valadi, Hadi, van Balkom, Bas W M, Vázquez, Jesús, Vidal, Michel, Wauben, Marca H M, Yáñez-Mó, María, Zoeller, Margot, Mathivanan, Suresh

“…Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of…”
Get full text

Sorting of Mannose 6-Phosphate Receptors and Lysosomal Membrane Proteins in Endocytic Vesicles by Geuze, Hans J., Stoorvogel, Willem, Strous, Ger J., Slot, Jan W., Bleekemolen, Jos E., Mellman, Ira

“…The intracellular distributions of the cation-independent mannose 6-phosphate receptor (MPR) and a 120-kD lysosomal membrane glycoprotein (lgp120) were studied…”
Get full text

Identification of subcellular compartments involved in biosynthetic processing of cathepsin D by RIJNBOUTT, S, STOORVOGEL, W, GEUZE, H. J, STROUS, G. J

“…We have assigned the biosynthetic processing steps of cathepsin D to intracellular compartments which are involved in its transport to lysosomes in HepG2…”
Get full text

Arguments in favour of endosome maturation by Stoorvogel, W

Get more information

Sphingomyelin synthase is absent from endosomes by van Helvoort, A, Stoorvogel, W, van Meer, G, Burger, N J

“…Both the Golgi and the endosomes have recently been proposed as the main site of SM-synthase, the enzyme responsible for sphingomyelin (SM) biosynthesis. To…”
Get full text

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation by Wubbolts, Richard, Leckie, Rachel S, Veenhuizen, Peter T M, Schwarzmann, Guenter, Möbius, Wiebke, Hoernschemeyer, Joerg, Slot, Jan-Willem, Geuze, Hans J, Stoorvogel, Willem

“…Exosomes are 60-100-nm membrane vesicles that are secreted into the extracellular milieu as a consequence of multivesicular body fusion with the plasma…”
Get full text

Relations between the Intracellular Pathways of the Receptors for Transferrin, Asialoglycoprotein, and Mannose 6-Phosphate in Human Hepatoma Cells by Stoorvogel, Willem, Geuze, Hans J., Griffith, Janice M., Schwartz, Alan L., Strous, Ger J.

“…We compared the intracellular pathways of the transferrin receptor (TfR) with those of the asialoglycoprotein receptor (ASGPR) and the cation-independent…”
Get full text

Sorting of Endocytosed Transferrin and Asialoglycoprotein Occurs Immediately after Internalization in HepG2 Cells by Stoorvogel, Willem, Geuze, Hans J., Strous, Ger J.

“…After receptor-mediated uptake, asialoglycoproteins are routed to lysosomes, while transferrin is returned to the medium as apotransferrin. This sorting…”
Get full text

The Biogenesis and Functions of Exosomes by Stoorvogel, Willem, Kleijmeer, Monique J., Geuze, Hans J., Raposo, Graça

“…Exosomes are membrane vesicles with a diameter of 40–100 nm that are secreted by many cell types into the extracellular milieu. They correspond to the internal…”
Get full text

The Pathways of Endocytosed Transferrin and Secretory Protein Are Connected in the trans-Golgi Reticulum by Stoorvogel, Willem, Geuze, Hans J., Griffith, Janice M., Strous, G. J.

“…We used a conjugate of transferrin and horseradish peroxidase (Tf/HRP) to label the intracellular transferrin receptor route in the human hepatoma cell line…”
Get full text

Exosomes contain ubiquitinated proteins by Buschow, Sonja I., Liefhebber, Jolanda M.P., Wubbolts, Richard, Stoorvogel, Willem

“…Multivesicular bodies (MVB) are endosomal compartments that contain multiple vesicles, which derive from a delimiting membrane by inward budding. Incorporation…”
Get full text