Search Results - "Stoner, Matthew A."

Multicomponent folate-targeted magnetoliposomes: design, characterization, and cellular uptake by Bothun, Geoffrey D., PhD, Lelis, Alline, BS, Chen, Yanjing, PhD, Scully, Kyle, BS, Anderson, Linnea E., MS, Stoner, Matthew A., PhD

“…Abstract Folate-targeted cationic magnetoliposomes (FTMLs) have been prepared with coencapsulated doxorubicin (DOX) and anionic superparamagnetic iron oxide…”
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Rational quantitative structure–activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands by Dring, Ann M., Anderson, Linnea E., Qamar, Saima, Stoner, Matthew A.

“…▶ CAR1 and CAR3 isoform-specific ligand effects are shown in the context of their activities with PXR. ▶ Identified 31 compounds with different ligand effects…”
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Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR) by Anderson, Linnea E., Dring, Ann M., Hamel, Laura D., Stoner, Matthew A.

“…► Benzothiazepine ligands of the mitochondrial PBR also modulate CAR and PXR ► The benzothiazepine, NF49, is a selective agonist of CAR3, versus CAR1 or PXR ►…”
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Estrogenic chemicals often leach from BPA-free plastic products that are replacements for BPA-containing polycarbonate products by Bittner, George D, Yang, Chun Z, Stoner, Matthew A

“…Xenobiotic chemicals with estrogenic activity (EA), such as bisphenol A (BPA), have been reported to have potential adverse health effects in mammals,…”
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Chemicals having estrogenic activity can be released from some bisphenol A-free, hard and clear, thermoplastic resins by Bittner, George D, Denison, Michael S, Yang, Chun Z, Stoner, Matthew A, He, Guochun

“…Chemicals that have estrogenic activity (EA) can potentially cause adverse health effects in mammals including humans, sometimes at low doses in fetal through…”
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Hepatoma Cell Uptake of Cationic Multifluorescent Quantum Dot Liposomes by Bothun, Geoffrey D., Rabideau, Amy E., Stoner, Matthew A.

“…Cationic multifluorescent quantum dot liposomes (QD-Ls) have been prepared with both hydrophobic and hydrophilic CdSe/ZnS quantum dots by reverse phase…”
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A robotic BG1Luc reporter assay to detect estrogen receptor agonists by Stoner, Matthew A., Yang, Chun Z., Bittner, George D.

“…•Chemicals with estogenic activity (EA) potentially have adverse health effects.•A robotic BG1Luc assay was developed to detect EA in chemicals or chemical…”
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Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3) by Auerbach, Scott S, Stoner, Matthew A, Su, Shengzhong, Omiecinski, Curtis J

“…The constitutive androstane receptor (CAR) mediates the hepatic induction of various xenobiotic metabolizing enzymes and transporters after specific chemical…”
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A robotic MCF-7:WS8 cell proliferation assay to detect agonist and antagonist estrogenic activity by Yang, Chun Z, Casey, Warren, Stoner, Matthew A, Kollessery, Gayathri J, Wong, Amy W, Bittner, George D

“…Endocrine-disrupting chemicals with estrogenic activity (EA) or anti-EA (AEA) have been extensively reported to possibly have many adverse health effects. We…”
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Alternatively spliced isoforms of the human constitutive androstane receptor by Auerbach, Scott S., Ramsden, Richard, Stoner, Matthew A., Verlinde, Christophe, Hassett, Christopher, Omiecinski, Curtis J.

“…The nuclear receptor CAR (NR1I3) regulates transcription of genes encoding xenobiotic‐ and steroid‐metabolizing enzymes. Regulatory processes that are mediated…”
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CAR2 displays unique ligand binding and RXRα heterodimerization characteristics by AUERBACH, Scott S, DEKEYSER, Joshua G, STONER, Matthew A, OMIECINSKI, Curtis J

“…The constitutive androstane receptor (CAR; NR1I3) regulates the expression of genes involved in xenobiotic metabolism. Alternative splicing of the human CAR…”
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Transactivation of a DR-1 PPRE by a human constitutive androstane receptor variant expressed from internal protein translation start sites by Stoner, Matthew A., Auerbach, Scott S., Zamule, Stephanie M., Strom, Stephen C., Omiecinski, Curtis J.

“…Downstream in-frame start codons produce amino-terminal-truncated human constitutive androstane receptor protein isoforms (ΔNCARs). The ΔNCARs are expressed in…”
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CAR2 displays unique ligand binding and RXRα heterodimerization characteristics by Dekeyser, Joshua Gordon, Auerbach, Scott S., Stoner, Matthew A., Omiecinski, Curtis J.

“…The constitutive androstane receptor (CAR, NR1I3) regulates the expression of genes involved in all phases of xenobiotic metabolism. Alternative splicing of…”
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CAR2 Displays Unique Ligand Binding and RXRα Heterodimerization Characteristics by Scott S. Auerbach, Joshua G. DeKeyser, Matthew A. Stoner, Curtis J. Omiecinski

“…The constitutive androstane receptor (CAR; NR1I3) regulates the expression of genes involved in xenobiotic metabolism. Alternative splicing of the human CAR…”
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CAR2 displays unique ligand binding and RXRalpha heterodimerization characteristics by Auerbach, Scott S, Dekeyser, Joshua G, Stoner, Matthew A, Omiecinski, Curtis J

“…The constitutive androstane receptor (CAR; NR1I3) regulates the expression of genes involved in xenobiotic metabolism. Alternative splicing of the human CAR…”
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Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo2,1-d1,5benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR) by Anderson, Linnea E, Dring, Ann M, Hamel, Laura D, Stoner, Matthew A

“…Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) regulate xenobiotic sensing and metabolism through interactions with multiple exogenous…”
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