Search Results - "Stoneman, Rhys G"

Sequence and Structural Duality:  Designing Peptides to Adopt Two Stable Conformations by Pandya, Maya J, Cerasoli, Eleonora, Joseph, Abbey, Stoneman, Rhys G, Waite, Eleanor, Woolfson, Derek N

“…To improve our understanding of conformational transitions in proteins, we are attempting the de novo design of peptides that switch structural state. Here, we…”
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Protein-Small Molecule Interactions in Neocarzinostatin, the Prototypical Enediyne Chromoprotein Antibiotic by Baker, James R., Woolfson, Derek N., Muskett, Frederick W., Stoneman, Rhys G., Urbaniak, Michael D., Caddick, Stephen

“…The enediyne chromoproteins are a class of potent antitumour antibiotics comprising a 1:1 complex of a protein and a noncovalently bound chromophore. The…”
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Synthetic Ligands for Apo-Neocarzinostatin by Caddick, Stephen, Muskett, Frederick W, Stoneman, Rhys G, Woolfson, Derek N

“…Neocarzinostatin (NCS) is a 1:1 complex of an enediyne chromophore (NCSChrom), non-covalently bound to an 11 kDa protein (apoNCS). We are exploring apoNCS as a…”
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