Search Results - "Stonelake, Paul S"

The hypercoagulable state of malignancy: pathogenesis and current debate by Caine, Graham J, Stonelake, Paul S, Lip, Gregory Y H, Kehoe, Sean T

“…A hypercoagulable or prothrombotic state of malignancy occurs due to the ability of tumor cells to activate the coagulation system. It has been estimated that…”
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Circulating Endothelial Cells and Circulating Progenitor Cells in Breast Cancer: Relationship to Endothelial Damage/Dysfunction/ Apoptosis, Clinicopathologic Factors, and the Nottingham Prognostic Index by Goon, Patrick K.Y., Lip, Gregory Y.H., Stonelake, Paul S., Blann, Andrew D.

“…BACKGROUND AND METHODS: Abnormal circulating endothelial cell (CEC) and circulating progenitor cell (CPC) numbers are present in cancer, but their relationship…”
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Detection and quantification of mature circulating endothelial cells using flow cytometry and immunomagnetic beads: a methodological comparison by Goon, Patrick K Y, Boos, Christopher J, Stonelake, Paul S, Blann, Andrew D, Lip, Gregory Y H

“…Mature circulating endothelial cells (CECs) are novel cellular markers of endothelial damage/dysfunction. The two main techniques of CEC enumeration are flow…”
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Platelet activation, coagulation and angiogenesis in breast and prostate carcinoma by Caine, Graham J, Lip, Gregory Y H, Stonelake, Paul S, Ryan, Peter, Blann, Andrew D

“…In health, haemostasis and angiogenesis are tightly regulated processes, but may become deregulated in cancer. Recent evidence suggests that platelet…”
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Coagulopathic complications in breast cancer by Caine, Graham J., Stonelake, Paul S., Rea, Daniel, Lip, Gregory Y. H.

“…Patients with cancer are highly susceptible to thromboembolic complications, which account for a significant percentage of the morbidity and mortality of the…”
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Angiogenin outperforms VEGF, EPCs and CECs in predicting Dukes' and AJCC stage in colorectal cancer by Ramcharan, Sean K., Lip, Gregory Y. H., Stonelake, Paul S., Blann, Andrew D.

“…Background Circulating endothelial cells (CECs), endothelial progenitor cells (EPCs), Willebrand factor (vWf), soluble E‐selectin, vascular endothelial growth…”
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Use of Multiple Drains After Mastectomy Is Associated With More Patient Discomfort and Longer Postoperative Stay by Saratzis, Athanasios, Soumian, Soni, Willetts, Rachel, Sarah Rastall, Sarah, Stonelake, Paul S

“…Abstract Background Seromas constitute a common complication following surgery for breast cancer, and closed drainage is used routinely to reduce its…”
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The endotheliome: A new concept in vascular biology by Ramcharan, Khedar S, Lip, Gregory Y.H, Stonelake, Paul S, Blann, Andrew D

“…Abstract As the importance of the endothelium is becoming increasingly recognised, additional tools are needed to assess its functions. Separate studies have…”
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Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer by Caine, Graham J, Stonelake, Paul S, Lip, Gregory Y.H, Blann, Andrew D

“…Abstract Background Vascular endothelial growth factor (VEGF), a major angiogenic growth factor, is involved in the pathogenesis of cancer. Plasma VEGF is…”
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Hypertension, anti-hypertensive therapy and neoplasia by Goon, Patrick K Y, Stonelake, Paul S, Lip, Gregory Y H

“…The link between cancer, hypertension and anti-hypertensive drug treatment is controversial. Despite numerous studies looking either directly or indirectly at…”
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A comparison of plasma versus histologic indices of angiogenic markers in breast cancer by Caine, Graham J, Lip, Gregory, Zanetto, Ulyses, Maheshwari, Mahwandra, Stonelake, Paul S, Blann, Andrew D

“…Over-expression of angiogenic growth factors and their receptors, and high levels of these molecules in the blood, are a common feature of cancer although the…”
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Circulating endothelial cells in malignant disease by Goon, Patrick K Y, Boos, Christopher J, Stonelake, Paul S, Lip, Gregory Y H

“…Cancer is a disease largely dependent on neoangiogenesis. Cancer neoangiogenesis is often disordered and abnormal, with evidence of coexisting vascular…”
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The quest for circulating endothelial cell standardization: The peril of platelets by Goon, Patrick K. Y., Watson, Timothy, Stonelake, Paul S., Lip, Gregory Y. H.

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Tamoxifen for breast-cancer prevention by Caine, Graham J, Blann, Andrew D, Stonelake, Paul S, Kehoe, Sean T, Lip, Gregory YH

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Platelet adhesion in breast cancer: development and application of a novel assay by Caine, Graham J, Nadar, Sunil K, Lip, Gregory YH, Stonelake, Paul S, Blann, Andrew D

“…The increased risk of thromboembolism in cancer may be related to a prothrombotic or hypercoagulable state, with abnormalities of haemostasis and platelet…”
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Tamoxifen for breast-cancer prevention by Cykert, Samuel

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Angiogenin outperforms VEGF , EPC s and CEC s in predicting D ukes' and AJCC stage in colorectal cancer by Ramcharan, Sean K., Lip, Gregory Y. H., Stonelake, Paul S., Blann, Andrew D.

“…Abstract Background Circulating endothelial cells ( CEC s), endothelial progenitor cells ( EPC s), W illebrand factor (v W f), soluble E ‐selectin, vascular…”
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A prospective study of the value of axillary node sampling in addition to sentinel lymph node biopsy in patients with breast cancer by Hoar, F.J., Stonelake, P.S.

“…Aims: Limitations of sentinel lymph node biopsy (SLNB) include the occurrence of false negative (FN) results and the need to further treat SLNB positive…”
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The Hypercoagulable State of Malignancy: Pathogenesis and Current Debate1 by Caine, Graham J, Stonelake, Paul S, Lip, Gregory YH, Kehoe, Sean T

“…A hypercoagulable or prothrombotic state of malignancy occurs due to the ability of tumor cells to activate the coagulation system. It has been estimated that…”
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