Search Results - "Stonecypher, Mark S"

Human gastrin- releasing peptide receptor expression in women with uterine cervix cancer by Kunos, Charles A, Fabian, Denise, Napier, Dana, Stonecypher, Mark S, Duncan, Ravyn M, Hurt, Jason

“…Pb-DOTAM-GRPR1 is a pharmaceutical radioimmunoconjugate consisiting of an α-particle-emitting radionuclide lead-212 ( Pb), a metal chelator DOTAM…”
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Activation of the neuregulin-1 ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors by STONECYPHER, Mark S, BYER, Stephanie J, GRIZZLE, William E, CARROLL, Steven L

“…Patients with neurofibromatosis type 1 develop aggressive Schwann cell neoplasms known as malignant peripheral nerve sheath tumors (MPNSTs). Although tumor…”
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Tumor Suppressor Mutations and Growth Factor Signaling in the Pathogenesis of NF1-Associated Peripheral Nerve Sheath Tumors. I. The Role of Tumor Suppressor Mutations by CARROLL, STEVEN L, STONECYPHER, MARK S

“…Patients with neurofibromatosis type 1 (NF1), a common autosomal dominant tumor predisposition syndrome, develop benign cutaneous, intraneural, and plexiform…”
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Neuregulin Growth Factors and Their ErbB Receptors Form a Potential Signaling Network for Schwannoma Tumorigenesis by Stonecypher, Mark S, Chaudhury, Abhik Ray, Byer, Stephanie J, Carroll, Steven L

“…Sporadic and neurofibromatosis type 2-associated schwannomas contain a glial growth factor (GGF)-like activity that has been hypothesized to promote neoplastic…”
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Tumor Suppressor Mutations and Growth Factor Signaling in the Pathogenesis of NF1-Associated Peripheral Nerve Sheath Tumors: II. The Role of Dysregulated Growth Factor Signaling by Carroll, Steven L, Stonecypher, Mark S

“…Patients with neurofibromatosis type 1 (NF1), one of the most common genetic disease affecting the nervous system, develop multiple neurofibromas that can…”
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Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line by Frohnert, Paul W., Stonecypher, Mark S., Carroll, Steven L.

“…Neuregulin‐1 (NRG‐1) proteins promote Schwann cell survival, differentiation and proliferation during development. High levels of an NRG‐like activity are also…”
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Lysophosphatidic Acid Promotes the Proliferation of Adult Schwann Cells Isolated from Axotomized Sciatic Nerve by FROHNERT, PAUL W, STONECYPHER, MARK S, CARROLL, STEVEN L

“…We have previously found that adult Schwann cells express receptors for lysophosphatidic acid (EDG2, EDG7) and sphingosine-1-phosphate (EDG5) and that…”
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The prolyl isomerase Pin1 regulates the NF-κB signaling pathway and interleukin-8 expression in glioblastoma by Atkinson, G P, Nozell, S E, Harrison, D K, Stonecypher, M S, Chen, D, Benveniste, E N

“…The brain tumor glioblastoma (GBM) remains one of the most aggressive and devastating tumors despite decades of effort to find more effective treatments. A…”
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Activation of neuregulin -1/ErbB signaling promotes proliferation in human Schwann cell neoplasia by Stonecypher, Mark S

“…Neurofibromas, malignant peripheral nerve sheath tumors (MPNSTs), and schwannomas are three distinct types of peripheral nerve sheath tumors derived from…”
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