Search Results - "Stone, PJ"

Crosslinked α-elastin biomaterials: towards a processable elastin mimetic scaffold by Leach, Jennie B., Wolinsky, Jesse B., Stone, Phillip J., Wong, Joyce Y.

“…Elastin is a critical biochemical and biomechanical component of vascular tissue. However, elastin is also highly insoluble and therefore difficult to process…”
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Effect of soil temperature on phenology, canopy development, biomass and yield of maize in a cool-temperate climate by Stone, P.J., Sorensen, I.B., Jamieson, P.D.

“…The effect of soil temperature on maize phenology, canopy development, biomass and yield was examined by applying three treatments that altered soil…”
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Elastase Mediates the Release of Growth Factors from Lung In Vivo by Buczek-Thomas, Jo Ann, Lucey, Edgar C, Stone, Phillip J, Chu, Chia L, Rich, Celeste B, Carreras, Isabel, Goldstein, Ronald H, Foster, Judith A, Nugent, Matthew A

“…Uncontrolled elastase activity is involved in the development of several types of lung disease. Previous reports demonstrated that growth factors are liberated…”
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INTRACELLULAR COLONIZATION OF ROOTS OF ARABIDOPSIS AND CROP PLANTS BY GLUCONACETOBACTER DIAZOTROPHICUS by COCKING, EDWARD C., STONE, PHILIP J., DAVEY, MICHAEL R.

“…We have investigated the interaction of Gluconacetobacter diazotrophicus, a non-nodulating endophytic nitrogen-fixing bacterium isolated from the intercellular…”
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Elastase-released Epidermal Growth Factor Recruits Epidermal Growth Factor Receptor and Extracellular Signal-regulated Kinases to Down-regulate Tropoelastin mRNA in Lung Fibroblasts by DiCamillo, Sandra J., Carreras, Isabel, Panchenko, Maria V., Stone, Phillip J., Nugent, Matthew A., Foster, Judith A., Panchenko, Mikhail P.

“…Elastase/anti-elastase imbalance is a hallmark of emphysema, a chronic obstructive pulmonary disease associated with the rupture and inefficient repair of…”
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Effects of elastase on the mechanical and failure properties of engineered elastin-rich matrices by Black, Lauren D, Brewer, Kelly K, Morris, Shirley M, Schreiber, Barbara M, Toselli, Paul, Nugent, Matthew A, Suki, Bela, Stone, Phillip J

“…1 Department of Biomedical Engineering, Boston University, Boston; and 2 Department of Biochemistry, Boston University School of Medicine, Boston,…”
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Remodeling of alveolar walls after elastase treatment of hamsters: Results of elastin and collagen mRNA in situ hybridization by LUCEY, E. C, GOLDSTEIN, R. H, STONE, P. J, SNIDER, G. L

“…Treatment of hamster lungs with porcine pancreatic elastase (PPE) causes emphysema and a decrease in lung elastin content, which returns to control level by…”
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A(3) adenosine receptor deficiency does not influence atherogenesis by Jones, Matthew R, Zhao, Zhihui, Sullivan, Christopher P, Schreiber, Barbara M, Stone, Phillip J, Toselli, Paul A, Kagan, Herbert M, Cohen, Richard A, Ravid, Katya

“…Atherosclerosis is a multifactorial disease, the progression of which is modulated by several factors, including inflammation and hypercholesterolemia. The…”
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Hypoxia suppresses elastin repair by rat lung fibroblasts by Berk, John L, Hatch, Christine A, Morris, Shirley M, Stone, Phillip J, Goldstein, Ronald H

“…Macrophage and neutrophil proteinases damage lung elastin, disrupting alveolar epithelium and filling alveoli with inflammatory exudate. Alveolar collapse and…”
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Potential use of collagen and elastin degradation markers for monitoring liver fibrosis in schistosomiasis by Stone, Phillip J

“…Liver fibrosis is a serious complication of schistosomiasis infection, is associated with increased amounts of collagen and the collagen cross-link,…”
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Urinary desmosine excretion in smokers with and without rapid decline of lung function: the Normative Aging Study by Gottlieb, D J, Stone, P J, Sparrow, D, Gale, M E, Weiss, S T, Snider, G L, O'Connor, G T

“…It is hypothesized that smoking-related chronic obstructive pulmonary disease (COPD) results in part from excess lung elastin degradation. Taking advantage of…”
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Effects of glucosinolates and flavonoids on colonization of the roots of Brassica napus by Azorhizobium caulinodans ORS571 by O'CALLAGHAN, K. J, STONE, P. J, XIAOJIA HU, GRIFFITHS, D. W, DAVEY, M. R, COCKING, E. C

“…Plants of Brassica napus were assessed quantitatively for their susceptibility to lateral root crack colonization by Azorhizobium caulinodans ORS571(pXLGD4) (a…”
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Heparan sulfate depletion within pulmonary fibroblasts: Implications for elastogenesis and repair by Buczek-Thomas, Jo Ann, Chu, Chia L., Rich, Celeste B., Stone, Phillip J., Foster, Judith A., Nugent, Matthew A.

“…We investigated the role of sulfated proteoglycans in regulating extracellular matrix (ECM) deposition in pulmonary fibroblast cultures. Fibroblast cultures…”
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B-Myb Represses Elastin Gene Expression in Aortic Smooth Muscle Cells by Hofmann, Claudia S, Wang, Xiaobo, Sullivan, Christopher P, Toselli, Paul, Stone, Phillip J, McLean, Sean E, Mecham, Robert P, Schreiber, Barbara M, Sonenshein, Gail E

“…B-Myb represses collagen gene transcription in vascular smooth muscle cells (SMCs) in vitro and in vivo . Here we sought to determine whether elastin is…”
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B-Myb Represses Vascular Smooth Muscle Cell Collagen Gene Expression and Inhibits Neointima Formation After Arterial Injury by Hofmann, Claudia S, Sullivan, Christopher P, Jiang, Hao-Yuan, Stone, Phillip J, Toselli, Paul, Reis, Ernane D, Chereshnev, Igor, Schreiber, Barbara M, Sonenshein, Gail E

“…OBJECTIVES—The function of B-Myb, a negative regulator of vascular smooth muscle cell (SMC) matrix gene transcription, was analyzed in the vasculature. METHODS…”
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Building Elastin . Incorporation of Recombinant Human Tropoelastin into Extracellular Matrices using Nonelastogenic Rat-1 Fibroblasts as a Source for Lysyl Oxidase by Stone, Phillip J, Morris, Shirley M, Griffin, Susan, Mithieux, Suzanne, Weiss, Anthony S

“…The purpose of this study was to assess the feasibility of crosslinking exogenously produced tropoelastin, the precursor of insoluble elastin, into existing…”
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Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease by Stone, P J, Gottlieb, D J, O'Connor, G T, Ciccolella, D E, Breuer, R, Bryan-Rhadfi, J, Shaw, H A, Franzblau, C, Snider, G L

“…It has been hypothesized that emphysema results from damage to the elastic fiber network of the lungs as a result of elastase-antielastase imbalance. We used a…”
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Yield response to nutrient supply across a wide range of conditions: 2. Analysis of maize yields by Reid, J.B, Stone, P.J, Pearson, A.J, Wilson, D.R

“…This paper tests PARJIB, a simple but powerful model to analyse and forecast yield responses to nutrients in annual crops. The model was calibrated for maize…”
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Azorhizobium caulinodans ORS571 colonizes the xylem of Arabidopsis thaliana by STONE, Philip J, O'CALLAGHAN, Kenneth J, DAVEY, Michael R, COCKING, Edward C

“…Improved conditions were used for the aseptic growth of Arabidopsis thaliana to investigate whether xylem colonization of A. thaliana by Azorhizobium…”
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Elastin and collagen degradation products in urine of patients with cystic fibrosis by Stone, P J, Konstan, M W, Berger, M, Dorkin, H L, Franzblau, C, Snider, G L

“…Elastin degradation has been reported to be increased in patients with cystic fibrosis (CF). In order to further explore evidence for elastin degradation in a…”
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