Search Results - "Stone, P J"

Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells by Song, L L, Peng, Y, Yun, J, Rizzo, P, Chaturvedi, V, Weijzen, S, Kast, W M, Stone, P J B, Santos, L, Loredo, A, Lendahl, U, Sonenshein, G, Osborne, B, Qin, J-Z, Pannuti, A, Nickoloff, B J, Miele, L

“…Notch-1 inhibits apoptosis in some transformed cells through incompletely understood mechanisms. Notch-1 can increase nuclear factor-kappa B (NF-κB) activity…”
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Normothermic ex vivo perfusion of the limb allograft depletes donor leukocytes prior to transplantation by Amin, KR, Stone, JP, Kerr, JC, Wong, JK, Fildes, JE

“…The donor immune compartment plays a central role in graft rejection of the vascularised composite allograft (VCA) by contributing to ‘direct presentation’…”
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Desmosine as a biomarker of elastin degradation in COPD: current status and future directions by Luisetti, M, Ma, S, Iadarola, P, Stone, P. J, Viglio, S, Casado, B, Lin, Y. Y, Snider, G. L, Turino, G. M

“…Desmosine (DES) and isodesmosine (IDES) are two unusual, tetrafunctional, pyridinium ring-containing amino acids involved in elastin cross-linking. Being amino…”
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Randomized preclinical study of machine perfusion in vascularized composite allografts by Amin, K R, Stone, J P, Kerr, J, Geraghty, A, Joseph, L, Montero-Fernandez, A, Wong, J K, Fildes, J E

“…Attempts to improve limb preservation for transplantation using ex vivo perfusion have yielded promising results. However, metabolic acidosis, aberrant…”
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Altered Immunogenicity of Donor Lungs via Removal of Passenger Leukocytes Using Ex Vivo Lung Perfusion by Stone, J. P., Critchley, W. R., Major, T., Rajan, G., Risnes, I., Scott, H., Liao, Q., Wohlfart, B., Sjöberg, T., Yonan, N., Steen, S., Fildes, J. E.

“…Passenger leukocyte transfer from the donor lung to the recipient is intrinsically involved in acute rejection. Direct presentation of alloantigen expressed on…”
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Recurarization in the recovery room following the use of magnesium sulphate by Fawcett, W. J., Stone, J. P.

“…A 67-yr-old man weighing 104 kg, with a history of hypertension, underwent laparoscopic cholecystectomy. His preoperative serum potassium was 3.4 mmol litre−1…”
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P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer by STONE, J. P, WAGNER, D. D

“…Activated platelets and stimulated endothelial cells express P-selectin, an integral membrane protein receptor that binds monocytes and neutrophils. P-selectin…”
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Remodeling of alveolar walls after elastase treatment of hamsters: Results of elastin and collagen mRNA in situ hybridization by LUCEY, E. C, GOLDSTEIN, R. H, STONE, P. J, SNIDER, G. L

“…Treatment of hamster lungs with porcine pancreatic elastase (PPE) causes emphysema and a decrease in lung elastin content, which returns to control level by…”
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Urinary desmosine excretion in smokers with and without rapid decline of lung function: the Normative Aging Study by Gottlieb, D J, Stone, P J, Sparrow, D, Gale, M E, Weiss, S T, Snider, G L, O'Connor, G T

“…It is hypothesized that smoking-related chronic obstructive pulmonary disease (COPD) results in part from excess lung elastin degradation. Taking advantage of…”
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Effects of glucosinolates and flavonoids on colonization of the roots of Brassica napus by Azorhizobium caulinodans ORS571 by O'CALLAGHAN, K. J, STONE, P. J, XIAOJIA HU, GRIFFITHS, D. W, DAVEY, M. R, COCKING, E. C

“…Plants of Brassica napus were assessed quantitatively for their susceptibility to lateral root crack colonization by Azorhizobium caulinodans ORS571(pXLGD4) (a…”
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Robotic Radical Trachelectomy for Preservation of Fertility in Early Cervical Cancer: Case Series and Description of Technique by Burnett, A.F., MD, Stone, P.J., MD, Duckworth, L.A., MD, Roman, J.J., MD

“…Abstract Study Objective To present a case series of robotic radical trachelectomy for preservation of fertility in early cervical cancer. Design Descriptive…”
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Building Elastin . Incorporation of Recombinant Human Tropoelastin into Extracellular Matrices using Nonelastogenic Rat-1 Fibroblasts as a Source for Lysyl Oxidase by Stone, Phillip J, Morris, Shirley M, Griffin, Susan, Mithieux, Suzanne, Weiss, Anthony S

“…The purpose of this study was to assess the feasibility of crosslinking exogenously produced tropoelastin, the precursor of insoluble elastin, into existing…”
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Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease by Stone, P J, Gottlieb, D J, O'Connor, G T, Ciccolella, D E, Breuer, R, Bryan-Rhadfi, J, Shaw, H A, Franzblau, C, Snider, G L

“…It has been hypothesized that emphysema results from damage to the elastic fiber network of the lungs as a result of elastase-antielastase imbalance. We used a…”
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Human Neutrophil Elastase Releases Cell Surface Mucins from Primary Cultures of Hamster Tracheal Epithelial Cells by Kim, Kwang C., Wasano, Kojiro, Niles, Richard M., Schuster, Jonathan E., Stone, Phillip J., Brody, Jerome S.

“…Primary hamster tracheal epithelial cells growing on a collagen gel matrix produce high molecular weight mucins indistinguishable from mucins produced in vivo…”
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Immunocytochemical study of the degradation of elastic fibers in a living extracellular matrix by Morris, SM, Stone, PJ

“…We used ultrastructural and immunocytochemical technique to follow the movement of human neutrophil elastase (HNE) and porcine pancreatic elastase (PPE)…”
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Azorhizobium caulinodans ORS571 colonizes the xylem of Arabidopsis thaliana by STONE, Philip J, O'CALLAGHAN, Kenneth J, DAVEY, Michael R, COCKING, Edward C

“…Improved conditions were used for the aseptic growth of Arabidopsis thaliana to investigate whether xylem colonization of A. thaliana by Azorhizobium…”
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Elastin and collagen degradation products in urine of patients with cystic fibrosis by Stone, P J, Konstan, M W, Berger, M, Dorkin, H L, Franzblau, C, Snider, G L

“…Elastin degradation has been reported to be increased in patients with cystic fibrosis (CF). In order to further explore evidence for elastin degradation in a…”
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Heat-shock protein 70 and dough-quality changes resulting from heat stress during grain filling in wheat by Blumenthal, C. (CSIRO Plant Industry, North Ryde, NSW, Australia.), Stone, P.J, Gras, P.W, Bekes, F, Clarke, B, Barlow, E.W.R, Appels, R, Wrigley, C.W

“…In an attempt to further elucidate the molecular mechanisms that determine the loss of dough strength associated with heat stress of growing wheat, the roles…”
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The preparation and storage of anaesthetic drugs for obstetric emergencies: a survey of UK practice by Stone, J.P, Fenner, L.B, Christmas, T.R

“…Abstract Background Traditionally anaesthetic drugs for obstetrics are prepared as a contingency and stored until they are required for emergency use or have…”
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Cloning and sequence analysis of the glucoamylase gene of Neurospora crassa by Stone, P.J. (Leeds Univ. (United Kingdom). Dept. of Biochemistry and Molecular Biology), Makoff, A.J, Parish, J.H, Radford, A

“…A 1.0-kb DNA fragment, corresponding to an internal region of the Neurospora crassa glucoamylase gene, gla-1, was generated from genomic DNA by the polymerase…”
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