Search Results - "Stone, Natalie L"

Pancreatic β-Cell Function and Immune Responses to Insulin After Administration of Intranasal Insulin to Humans At Risk for Type 1 Diabetes by HARRISON, Leonard C, HONEYMAN, Margo C, STEELE, Cheryl E, STONE, Natalie L, SARUGERI, Elena, BONIFACIO, Ezio, COUPER, Jennifer J, COLMAN, Peter G

“…Pancreatic β-Cell Function and Immune Responses to Insulin After Administration of Intranasal Insulin to Humans At Risk for Type 1 Diabetes Leonard C. Harrison…”
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High-Performance Workflow for Identifying Site-Specific Crosslinks Originating from a Genetically Incorporated, Photoreactive Amino Acid by Ulmer, Lindsey D., Canzani, Daniele, Woods, Christopher N., Stone, Natalie L., Janowska, Maria K., Klevit, Rachel E., Bush, Matthew F.

“…In conventional crosslinking mass spectrometry, proteins are crosslinked using a highly selective, bifunctional chemical reagent, which limits crosslinks to…”
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CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function by Bandala-Sanchez, Esther, Bediaga, Naiara G., Goddard-Borger, Ethan D., Ngui, Katrina, Naselli, Gaetano, Stone, Natalie L., Neale, Alana M., Pearce, Lesley A., Wardak, Ahmad, Czabotar, Peter, Haselhorst, Thomas, Maggioni, Andrea, Hartley-Tassell, Lauren A., Adams, Timothy E., Harrison, Leonard C.

“…CD52, a glycophosphatidylinositol (GPI)-anchored glycoprotein, is released in a soluble form following T cell activation and binds to the Siglec (sialic…”
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Cytotoxicity-Related Gene Expression and Chromatin Accessibility Define a Subset of CD4+ T Cells That Mark Progression to Type 1 Diabetes by Bediaga, Naiara G, Garnham, Alexandra L, Naselli, Gaetano, Bandala-Sanchez, Esther, Stone, Natalie L, Cobb, Joanna, Harbison, Jessica E, Wentworth, John M, Ziegler, Annette-G, Couper, Jennifer J, Smyth, Gordon K, Harrison, Leonard C

“…Type 1 diabetes in children is heralded by a preclinical phase defined by circulating autoantibodies to pancreatic islet antigens. How islet autoimmunity is…”
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Evidence for Molecular Mimicry between Human T Cell Epitopes in Rotavirus and Pancreatic Islet Autoantigens by Honeyman, Margo C, Stone, Natalie L, Falk, Ben A, Nepom, Gerald, Harrison, Leonard C

“…In type 1 diabetes, insulin-producing beta cells in the islets of the pancreas are destroyed by autoreactive T cells. Rotavirus (RV) has been implicated in the…”
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A surge in serum mucosal cytokines associated with seroconversion in children at risk for type 1 diabetes by Harrison, Leonard C, Bandala‐Sanchez, Esther, Oakey, Helena, Colman, Peter G, Watson, Kelly, Kim, Ki Wook, Wu, Roy, Hamilton‐Williams, Emma E, Stone, Natalie L, Haynes, Aveni, Thomson, Rebecca L, Vuillermin, Peter J, Soldatos, Georgia, Rawlinson, William D, McGorm, Kelly J, Morahan, Grant, Barry, Simon C, Sinnott, Richard O, Wentworth, John M, Couper, Jennifer J, Penno, Megan AS, Barry, Simon C, Craig, Maria E, Colman, Peter G, Couper, Jennifer J, Davis, Elizabeth A, Hamilton‐Williams, Emma, Harris, Mark, Harrison, Leonard C, Haynes, Aveni, Kim, Ki Wook, Morahan, Grant, Oakey, Helena, Penno, Megan A S, Rawlinson, William D, Sinnott, Richard O, Soldatos, Georgia, Thomson, Rebecca L, Vuillermin, Peter J, Anderson, Amanda J, Ashwood, Pat, Brown, James D, Hu, William, Huynh, Dao, McGorm, Kelly J, Watson, Kelly, Tye‐Din, Jason, Huynh, Tony, Morbey, Claire, Lopez, Prudence, Beresford, Sarah, Bertram, Samantha, Bezuidenhout, Debra, Brandrick, Susan, Butterworth, Carlie, Catteau, Jacki, Clements, Nakita, Gartrell, Kyana, Gilbert, Abbey, Griffiths, Helen, Gwiazdzinski, Alison, Hall, Candice, Harper, Gail, Hulley, Amanda, Hoffman, Mikayla, Kludas, Renee, Moore, Belinda, Ramoso, Benjamin, Roberts, Alison, Tully, Alexandra, Vicary, Isabelle, Wood, Rosemary, Battersby, Rachel, Hope, Chris, Sadlon, Tim, Roth‐Schulze, Alexandra, Wong, Ying‐Ying, Zozaya‐Valdes, Enrique, Binkowski, Sabrina, Brittain, Bek, Bui, Minh, Minhaj, Asma, Naselli, Gaetano, Ngui, Katrina, Nguyen, Trung, Stone, Natalie, Ward, Emily, Xu, Yan, Yau, Cynthia

“…ABSTRACT Aims/Introduction Autoantibodies to pancreatic islet antigens identify young children at high risk of type 1 diabetes. On a background of genetic…”
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Antigen-Based Vaccination and Prevention of Type 1 Diabetes by Harrison, Leonard C., Wentworth, John M., Zhang, Yuxia, Bandala-Sanchez, Esther, Böhmer, Ralph M., Neale, Alana M., Stone, Natalie L., Naselli, Gaetano, Bosco, Julian J., Auyeung, Priscilla, Rashidi, Maryam, Augstein, Petra, Morahan, Grant

“…Insulin-dependent or type 1 diabetes (T1D) is a paradigm for prevention of autoimmune disease: Pancreatic β-cell autoantigens are defined, at-risk individuals…”
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Neural network-based prediction of candidate T-cell epitopes by Honeyman, Margo C, Brusic, Vladimir, Stone, Natalie L, Harrison, Leonard C

“…Activation of T cells requires recognition by T-cell receptors of specific peptides bound to major histocompatibility complex (MHC) molecules on the surface of…”
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CD4+ T Cell Proliferation in Response to GAD and Proinsulin in Healthy, Pre-diabetic, and Diabetic Donors by MANNERING, STUART I., MORRIS, JESSICA S., STONE, NATALIE L., JENSEN, KENT P., VAN ENDERT, PETER M., HARRISON, LEONARD C.

“…: The ability to measure proliferation of autoantigen‐specific T cells is critical for the evaluation of cellular immune function. Using a novel, sensitive,…”
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Type 1 diabetes: a disease of developmental origins by Phillips, Jessica E., Couper, Jennifer J., Penno, Megan A.S., Harrison, Leonard C., Anderson, Heather, Bandala‐Sanchez, Esther, Barry, Simon C, Baskerville, Tracey, Battersby, Rachel, Bediaga, Naiara G, Bezuidenhout, Debra, Brownrigg, Emma, Catteau, Jacki, Choo, Ace, Colman, Peter G, Cotterill, Andrew, Couper, Jennifer J, Craig, Maria E, Curran, Sheryl, Davis, Elizabeth A, Dodd, Jodie M, Edwards, Danielle, French, Jane, Gibson, Emily, Giles, Lynne C, Gwiazdzinski, Alison, Harris, Mark, Harrison, Leonard C, Haynes, Aveni, Hope, Christopher M, Hsieh, Cecilia, Huang, Dexing, Hu, William, Keytash, Azita, Krieg, Meredith, Law, Soi C, Lloyd‐Johnsen, Catherine, Morahan, Grant, Neale, Alana M, Ngui, Katrina, Papenfuss, Anthony T, Penno, Megan AS, Poth, Megan, Ramoso, Benjamin, Rawlinson, William D, Roberts, Alison, Sadlon, Timothy J, Schulze, Alexandra, Penington, Jocelyn Sietsma, Sinnott, Richard O, Spooner, Kelly, Stone, Natalie L, Thomson, Rebecca L, Toome, Sarah, Tully, Alexandra, Vuillermin, Peter J, Watson, Kelly, Wentworth, John M, Wilson, Julianne

“…The incidence of type 1 diabetes globally has increased dramatically over the last 50 years. Proposed environmental reasons for this increase mirror the modern…”
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Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes by HONEYMAN, M. C, COULSON, B. S, STONE, N. L, GELLERT, S. A, GOLDWATER, P. N, STEELE, C. E, COUPER, J. J, TAIT, B. D, COLMAN, P. G, HARRISON, L. C

“…Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes. M C Honeyman , B S Coulson , N L…”
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T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents by Honeyman, M C, Stone, N L, Harrison, L C

“…The tyrosine phosphatase IA-2 is a molecular target of pancreatic islet autoimmunity in type 1 diabetes. T-cell epitope peptides in autoantigens have potential…”
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Pancreatic β-Cell Function and Immune Responses to Insulin After Administration of Intranasal Insulin to Humans At Risk for Type 1 Diabetes by Harrison, Leonard C, Honeyman, Margo C, Steele, Cheryl E, Stone, Natalie L

“…Mucosal administration of insulin retards development of autoimmune diabetes in the nonobese diabetic mouse model. Harrison et al conducted a double-blind…”
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CD4 super(+) T Cell Proliferation in Response to GAD and Proinsulin in Healthy, Pre-diabetic, and Diabetic Donors by Mannering, Stuart I, Morris, Jessica S, Stone, Natalie L, Jensen, Kent P, Van Endert, Peter M, Harrison, Leonard C

“…The ability to measure proliferation of autoantigen-specific T cells is critical for the evaluation of cellular immune function. Using a novel, sensitive,…”
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Evidence that Rotavirus Triggers Islet Autoimmunity by HONEYMAN, MARGO CAROLE, COULSON, BARBARA S, STONE, NATALIE L, STEELE, CHERYL, GELLERT, SHANE A, GOLDWATER, PAUL N, COUPER, JENNIFER J, DAVIDSON, GEOFFREY, COLMAN, PETER G, HARRISON, LEONARD C

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