Search Results - "Stone, J. A."

Rifampin's Acute Inhibitory and Chronic Inductive Drug Interactions: Experimental and Model-Based Approaches to Drug-Drug Interaction Trial Design by Reitman, ML, Chu, X, Cai, X, Yabut, J, Venkatasubramanian, R, Zajic, S, Stone, JA, Ding, Y, Witter, R, Gibson, C, Roupe, K, Evers, R, Wagner, JA, Stoch, A

“…We studied the time course for the reversal of rifampin's effect on the pharmacokinetics of oral midazolam (a cytochrome P450 (CYP) 3A4 substrate) and digoxin…”
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Ion mobility spectrometers in national defense by EICEMAN, G. A, STONE, J. A

“…Chemical measurements to detect explosives and chemical agents are part of the strategy to protect and secure nations. Ion mobility spectrometry is today one…”
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Microstructural and mechanical insight into atherosclerotic plaques: an ex vivo DTI study to better assess plaque vulnerability by Tornifoglio, B., Johnston, R. D., Stone, A. J., Kerskens, C., Lally, C.

“…Non-invasive microstructural characterisation has the potential to determine the stability, or lack thereof, of atherosclerotic plaques and ultimately aid in…”
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Model‐Based Characterization of the Pharmacokinetics of Pembrolizumab: A Humanized Anti–PD‐1 Monoclonal Antibody in Advanced Solid Tumors by Ahamadi, M, Freshwater, T, Prohn, M, Li, CH, de Alwis, DP, de Greef, R, Elassaiss‐Schaap, J, Kondic, A, Stone, JA

“…Pembrolizumab, a potent antibody against programmed death 1 (PD‐1) receptor, has shown robust antitumor activity and manageable safety in patients with…”
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The development of evidence-informed physical activity guidelines for adults with spinal cord injury by Ginis, K A Martin, Hicks, A L, Latimer, A E, Warburton, D E R, Bourne, C, Ditor, D S, Goodwin, D L, Hayes, K C, McCartney, N, McIlraith, A, Pomerleau, P, Smith, K, Stone, J A, Wolfe, D L

“…Objectives: To systematically develop evidence-informed physical activity guidelines to improve physical fitness in people with spinal cord injury (SCI)…”
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Age-related alterations in the cardiovascular responses to acute exercise in males and females: role of the exercise pressor reflex by Grotle, A. K., Langlo, J. V., Holsbrekken, E., Stone, A. J., Tanaka, H., Fadel, P. J.

“…Autonomic adjustments of the cardiovascular system are critical for initiating and sustaining exercise by facilitating the redistribution of blood flow and…”
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Safety, Tolerability, and Pharmacokinetics of Raltegravir After Single and Multiple Doses in Healthy Subjects by Iwamoto, M, Wenning, LA, Petry, AS, Laethem, M, De Smet, M, Kost, JT, Merschman, SA, Strohmaier, KM, Ramael, S, Lasseter, KC, Stone, JA, Gottesdiener, KM, Wagner, JA

“…Raltegravir is a novel human immunodeficiency virus‐1 integrase inhibitor with potent in vitro activity (95% inhibitory concentration (IC95)=33 nM in 50% human…”
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Grape seed extract and dried macroalgae, Ulva lactuca Linnaeus, improve survival of greenlip abalone, Haliotis laevigata Donovan, at high water temperature by Lange, Brett, Currie, Krishna-Lee, Howarth, Gordon S., Stone, David A.J.

“…Summer mortality (SM) in greenlip abalone (Haliotis laevigata Donovan) heavily affects productivity of land-based abalone farms in Southern Australia. It has…”
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The Inner Workings of the Outer Surface: Skin and Gill Microbiota as Indicators of Changing Gut Health in Yellowtail Kingfish by Legrand, Thibault P R A, Catalano, Sarah R, Wos-Oxley, Melissa L, Stephens, Fran, Landos, Matt, Bansemer, Matthew S, Stone, David A J, Qin, Jian G, Oxley, Andrew P A

“…The mucosal surfaces and associated microbiota of fish are an important primary barrier and provide the first line of defense against potential pathogens. An…”
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Effect of Moisture on the Field Dependence of Mobility for Gas-Phase Ions of Organophosphorus Compounds at Atmospheric Pressure with Field Asymmetric Ion Mobility Spectrometry by Krylova, N, Krylov, E, Eiceman, G. A, Stone, J. A

“…The electric field dependence of the mobilities of gas-phase protonated monomers [(MH+(H2O) n ] and proton-bound dimers [M2H+(H2O) n ] of organophosphorus…”
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Fiber deflection probe for small hole metrology by Muralikrishnan, B., Stone, J.A., Stoup, J.R.

“…This paper presents the development of a new probing method for coordinate measuring machines (CMM) to inspect the diameter and form of small holes. The…”
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Population Pharmacokinetic/Pharmacodynamic Modeling of Tumor Size Dynamics in Pembrolizumab‐Treated Advanced Melanoma by Chatterjee, MS, Elassaiss‐Schaap, J, Lindauer, A, Turner, DC, Sostelly, A, Freshwater, T, Mayawala, K, Ahamadi, M, Stone, JA, Greef, R, Kondic, AG, Alwis, DP

“…Pembrolizumab is a potent immune‐modulating antibody active in advanced melanoma, as demonstrated in the KEYNOTE‐001, ‐002, and ‐006 studies. Longitudinal…”
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An integrated ball projection technology for the study of dynamic interceptive actions by Stone, J. A., Panchuk, D., Davids, K., North, J. S., Fairweather, I., Maynard, I. W.

“…Dynamic interceptive actions, such as catching or hitting a ball, are important task vehicles for investigating the complex relationship between cognition,…”
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Inter-Tissue Differences in Fatty Acid Incorporation as a Result of Dietary Oil Manipulation in Port Jackson Sharks (Heterodontus portusjacksoni) by Beckmann, Crystal L., Mitchell, James G., Stone, David A. J., Huveneers, Charlie

“…Fatty acid profile analysis is a tool for dietary investigation that may complement traditional stomach contents analysis. While recent studies have shown that…”
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(De)synchronization of advanced visual information and ball flight characteristics constrains emergent information–movement couplings during one-handed catching by Stone, J. A., Maynard, I. W., North, J. S., Panchuk, D., Davids, K.

“…Advance visual information of a projection action and ball flight information is important for organizing dynamic interceptive actions like catching. However,…”
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Pharmacokinetics of Raltegravir in Individuals With UGT1A1 Polymorphisms by Wenning, LA, Petry, AS, Kost, JT, Jin, B, Breidinger, SA, DeLepeleire, I, Carlini, EJ, Young, S, Rushmore, T, Wagner, F, Lunde, NM, Bieberdorf, F, Greenberg, H, Stone, JA, Wagner, JA, Iwamoto, M

“…Raltegravir is a human immunodeficiency virus–1 (HIV‐1) integrase strand transfer inhibitor metabolized by glucuronidation via UDP‐glucuronosyltransferase 1A1…”
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Dietary fish oil replacement with palm or poultry oil increases fillet oxidative stability and decreases liver glutathione peroxidase activity in barramundi (Lates calcarifer) by Wan Ahmad, Wan A. R, Stone, David A. J, Schuller, Kathryn A

“…Complete dietary fish oil replacement with palm or poultry oil in barramundi (Lates calcarifer) had no detrimental effects on growth or hepatosomatic index of…”
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Chemical standards in ion mobility spectrometry by Eiceman, G.A, Nazarov, E.G, Stone, J.A

“…Positive ion mobility spectra for three compounds (2,4-dimethylpyridine (2,4-DMP, commonly called 2,4-lutidine), dimethyl methylphosphonate (DMMP) and 2,6-di-…”
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A comparison of the ion chemistry for mono-substituted toluenes and anilines by three methods of atmospheric pressure ionization with ion mobility spectrometry by Borsdorf, H., Neitsch, K., Eiceman, G.A., Stone, J.A.

“…Ion mobility spectra for a series of mono-substituted toluenes and a series of mono-substituted anilines were obtained using three different methods of…”
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Disease Systems Analysis of Bone Mineral Density and Bone Turnover Markers in Response to Alendronate, Placebo, and Washout in Postmenopausal Women by Berkhout, J, Stone, JA, Verhamme, KM, Danhof, M, Post, TM

“…A previously established mechanism‐based disease systems model for osteoporosis that is based on a mathematically reduced version of a model describing the…”
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